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Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett's esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week 2022.

13 May 2022

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

A bacteria calledStaphylococcusaureusis widespread and generally harmless, but can cause infections known as "opportunistic infections".

13 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

A new study has longitudinally traced and profiled the CD8+ T cell responses after COVID-19 mRNA booster vaccination.

13 May 2022

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Creating the industry’s first stem cell analysis update in nearly 25 years, Beckman Coulter Life Sciences – a global leader in laboratory automation and innovation – launches an evolution of the gold standard in hematopoietic stem cell enumeration, the AQUIOS STEM System.

13 May 2022

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

A team of scientists has recently studied the kinetic and thermodynamic characteristics of interaction between human ACE2 and spike receptor-binding domains of different variants of SARS-CoV-2.

13 May 2022

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

In a recent study posted to the bioRxiv* preprint server, researchers explored the role of the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein in SARS-CoV-2 fusion with the host membranes and coronavirus disease 2019 (COVID-19).

12 May 2022

Topical drugs may regress congenital giant nevi and prevent skin cancer

About one in 20,000 infants is born with what's called a congenital giant nevus - a huge, pigmented mole that may cover much of the face and body.

12 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

T-cell responses after COVID-19 and vaccinations

A new study published in the journal Frontiers in immunology examines the cell-mediated immunity in BNT162b2 COVID-19 mRNA vaccinated health care workers and COVID-19 patients.

12 May 2022

Study could provide a new approach to treating metastatic triple negative breast cancer

Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer.

12 May 2022

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

It is humbling to realize that we humans share about 70% of our genes with zebrafish. There are also a whole host of other similarities that make these small transparent fish an ideal animal model for the study of many human diseases and biological processes.

12 May 2022

Mathematical theory describes the process of checkpoint override by cells

Cells go through a life cycle that includes growing to the right size, being equipped to perform its functions, and finally dividing into two new cells.

12 May 2022

New therapeutic approach for cardiac repair after a heart attack

Following a heart attack, the human body is incapable of repairing lost tissue due to the heart's inability to generate new muscle.

12 May 2022

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

A WEHI-led study has identified a new enzyme involved in controlling cell death, in findings that could lead to better treatment options for a range of inflammatory conditions, cancers and viruses.

12 May 2022

Study shows how MS patients treated with Rituximab react to COVID-19 vaccination

MS patients treated with Rituximab have better responses to the COVID-19 vaccine if they have higher B cell counts.

12 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be used to deliver targeted medicines to human muscle cells.

12 May 2022

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

A new study has focussed on determining the clonality and levels of SARS-CoV-2-reactive CD4+ T cells in CCPs post-vaccination.

12 May 2022

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Researchers performed an unbiased evaluation of the early memory B cell repertoire specific for the Omicron and Delta variants of SARS-CoV-2.

12 May 2022

B Cell News and Research

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

Researchers discover new gene that confers resistance to prostate cancer treatment

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

Topical drugs may regress congenital giant nevi and prevent skin cancer

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

T-cell responses after COVID-19 and vaccinations

Study could provide a new approach to treating metastatic triple negative breast cancer

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

Mathematical theory describes the process of checkpoint override by cells

New therapeutic approach for cardiac repair after a heart attack

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

Study shows how MS patients treated with Rituximab react to COVID-19 vaccination

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

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