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New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

A new drug which could improve life expectancy and quality for patients with hard-to-treat cancers, such as pancreatic cancer and relapsed breast cancer, has been invented by scientists at the University of Sheffield.

9 Sep 2020

Study: Generic cholesterol medications save billions of dollars for Medicare

The switch from brand name to generic cholesterol medications that occurred between 2014 and 2018 has saved Medicare billions of dollars, even as the number of people on cholesterol-lowering drugs has increased, UT Southwestern scientists have calculated.

9 Sep 2020

BU study maps changes in homicide rates across Brazil

A new Boston University School of Public Health study maps changes in homicide rates across Brazil from 2000 through 2014.

8 Sep 2020

Environmental and biomedical applications of enzyme inhibitors

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for developing new therapeutic drugs.

8 Sep 2020

New bio-active natural products with huge potential as drugs

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives.

8 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

Using a pain reliever can increase risk-taking behavior

While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests.

8 Sep 2020

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

8 Sep 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

Microglia-targeting nanotherapeutics for treatment of neurodegenerative disorders

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

8 Sep 2020

Card-based system to track asymptomatic individuals helps reduce COVID-19 spread

The COVID-19 pandemic has had an adverse impact on the global economy. Researchers around the globe have been working hard to find ways to stop the spread of the disease either in the form of drugs or SOP changes that revolve around guidelines given by the WHO for maintaining hygiene and social distancing norms.

8 Sep 2020

Blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk

New research led by the University of South Australia shows that a blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk for the rest of their lives.

8 Sep 2020

Ghrelin may help protect the elderly population from muscle loss

The hormone, ghrelin, may help protect the elderly population from muscle loss, according to a study being presented at e-ECE 2020. The study found that administering a particular form of ghrelin to older mice helped to restore muscle mass and strength.

8 Sep 2020

Study addresses the role of macrophage activation syndrome in COVID-19

Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.

8 Sep 2020

Personalized determination of genetic factors may improve treatment for polycythaemia vera

Polycythaemia vera is a chronic malignant disease of the haematopoietic system and is treated with interferon-alpha-based drugs, in most cases with long-lasting success. However, in some cases this therapy is unsuccessful for reasons that are not yet understood.

8 Sep 2020

UV researchers patent a kit to detect GHB in alcoholic beverages and soft drinks

The MODeLiC (Organic Materials for Controlled Detection and Release) research team led by Ana María Costero, Professor of Organic Chemistry at the University of Valencia (UV), has developed a system with colorimetric sensors that change color when there is γ-hydroxybutyric acid (GHB) in a beverage.

8 Sep 2020

PI3K/mTOR and topoisomerase inhibitors suggested as candidates to reduce expression of ACE2

A recent study published in the preprint server medRxiv in September 2020 shows that the already approved drug families called P13K/mTOR and topoisomerase inhibitors may be useful in reducing individual susceptibility to the virus.

7 Sep 2020

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

Researchers developed a new class of medical instruments equipped with an advanced soft electronics system that could dramatically improve the diagnoses and treatments of a number of cardiac diseases and conditions.

7 Sep 2020

Polygenic risk score can predict risk of drug-induced liver injury

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

7 Sep 2020

Study shows how genetic data can be used to prioritize drug targets for complex diseases

An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit at the University of Bristol, has demonstrated how genetic data can be used to support drug target prioritisation by identifying the causal effects of proteins on diseases.

7 Sep 2020

Drugs News and Research

New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

Study: Generic cholesterol medications save billions of dollars for Medicare

BU study maps changes in homicide rates across Brazil

Environmental and biomedical applications of enzyme inhibitors

New bio-active natural products with huge potential as drugs

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Using a pain reliever can increase risk-taking behavior

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

Microglia-targeting nanotherapeutics for treatment of neurodegenerative disorders

Card-based system to track asymptomatic individuals helps reduce COVID-19 spread

Blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk

Ghrelin may help protect the elderly population from muscle loss

Study addresses the role of macrophage activation syndrome in COVID-19

Personalized determination of genetic factors may improve treatment for polycythaemia vera

UV researchers patent a kit to detect GHB in alcoholic beverages and soft drinks

PI3K/mTOR and topoisomerase inhibitors suggested as candidates to reduce expression of ACE2

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

Polygenic risk score can predict risk of drug-induced liver injury

Study shows how genetic data can be used to prioritize drug targets for complex diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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