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Spectrum Pharmaceuticals enters into agreement to acquire Talon Therapeutics

Spectrum Pharmaceuticals, Inc., a biotechnology company with fully-integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced that, through a wholly-owned subsidiary, the company entered into an agreement to acquire Talon Therapeutics, Inc., a biopharmaceutical company based in South San Francisco, California, and expects to complete the acquisition within one day.

17 Jul 2013

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

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17 Jul 2013

One step closer to understanding how to control cancer cells without harming healthy ones

The nasty side effects of radiation and chemotherapy are well known: fatigue, hair loss and nausea, to name a few. Cancer treatment can seem as harsh as the disease because it can't differentiate healthy cells from cancerous cells, killing both.

17 Jul 2013

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Companion test also approved to identify appropriate patients The U.S. Food and Drug Administration today approved Gilotrif (afatinib) for patients with late stage (metastatic) non-small cell lung cancer (NSCLC) whose tumors express specific types of epidermal growth factor receptor (EGFR) gene mutations, as detected by an FDA-approved test. Lung cancer is the leading cause of cancer-related death among men and women.

16 Jul 2013

Protein complex may be an effective alternative to opioid pain medications

A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to research led by the Icahn School of Medicine at Mount Sinai.

16 Jul 2013

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

16 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

A University of California, Riverside bioengineering professor has received a two-year, $120,000 grant to search for chemical compounds that have the potential to treat age-related macular degeneration.

12 Jul 2013

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive top-line results from its ongoing Phase I trial of ALN-TTRsc, a subcutaneously administered RNAi therapeutic targeting the transthyretin gene for the treatment of TTR-mediated amyloidosis.

12 Jul 2013

Researchers identify receptor mutation that blocked estrogen action in young woman

A receptor mutation that essentially blocks estrogen's action has been identified for the first time a female, researchers report.

12 Jul 2013

FDA issues warning on blood pressure drug, olmesartan medoxomil

Food and Drug Administration (FDA) regulators have issued a warning on the blood pressure drug known generically as olmesartan medoxomil. The drug can cause intestinal problems known as spruelike enteropathy, which has side effects including severe, chronic diarrhea and substantial weight loss, sometimes requiring hospitalization.

11 Jul 2013

Molecularly imprinted polymer receptors for nicotine recognition in biological systems

Researchers from the National Environmental Engineering Research Institute in Nehru Marg, India have added another piece to the puzzle of how to synthetize an artificial nicotine receptor.

10 Jul 2013

RUB chemists track interaction of enkephalin messengers with opioid receptor

"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, and opioid receptors is very difficult to study.

10 Jul 2013

Physicians have new resource for managing disease in patients with early-stage breast cancer

Physicians have a new resource for managing disease in patients with early-stage breast cancer. Patients diagnosed with ductal carcinoma in situ -- cancer that has not left the breast ducts -- now have the benefit of a multi-gene analysis that considers gene patterns to individualize therapy and determine the chance for recurrence, potentially sparing the patient additional therapy.

9 Jul 2013

ERC awards grants to boost research on vaccines

Vaccination has achieved huge success in controlling many devastating infectious diseases. However, there are still many such diseases, or 'pathogens', against which we cannot generate life-long protective immunity.

9 Jul 2013

Discovery of new receptor could turn the tide against mosquitoes' growing advantage

In the global war against disease-carrying mosquitoes, scientists have long believed that a single molecular door was the key target for insecticide. This door, however, is closing, giving mosquitoes the upper hand.

9 Jul 2013

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Two drugs, telmisartan and valsartan, which are used to reduce blood pressure in people with diabetes, are associated with a lower risk of hospitalization for heart attack, stroke or heart failure, according to a study published in CMAJ (Canadian Medical Association Journal).

9 Jul 2013

Soy peptide injection dramatically reduces colon cancer metastasis in mice

After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals' daily diet would affect the spread of the disease.

9 Jul 2013

Anti-cancer compounds offer hope for treating breast cancer

Melbourne researchers have discovered that anti-cancer compounds currently in clinical trials for some types of leukaemia could offer hope for treating the most common type of breast cancer.

9 Jul 2013

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, announced today the publication of pre-clinical data for VB-201 in the journal of Atherosclerosis.

8 Jul 2013

Receptor News and Research

Spectrum Pharmaceuticals enters into agreement to acquire Talon Therapeutics

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

One step closer to understanding how to control cancer cells without harming healthy ones

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Protein complex may be an effective alternative to opioid pain medications

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Researchers identify receptor mutation that blocked estrogen action in young woman

FDA issues warning on blood pressure drug, olmesartan medoxomil

Molecularly imprinted polymer receptors for nicotine recognition in biological systems

RUB chemists track interaction of enkephalin messengers with opioid receptor

Physicians have new resource for managing disease in patients with early-stage breast cancer

ERC awards grants to boost research on vaccines

Discovery of new receptor could turn the tide against mosquitoes' growing advantage

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Soy peptide injection dramatically reduces colon cancer metastasis in mice

Anti-cancer compounds offer hope for treating breast cancer

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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