B Cell News and Research

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Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more deadly.

10 May 2022

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Intestinal micro-biodiversity is important for maintaining colorectal and general health. Imbalance in this microenvironment can result in chronic infections, even cancer.

10 May 2022

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Alterations in metabolic processes are a hallmark of cancer and can lead to a tumor environment that is acidic. As a result, cancer cells must adapt to survive in this inhospitable environment.

10 May 2022

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an indicator for cancer and various other diseases.

10 May 2022

Cells do a little cleanup before mitosis

MIT researchers have discovered that before cells start to divide, they do a little cleanup, tossing out molecules that they appear not to need anymore.

10 May 2022

Testicular tissue can be successfully frozen for over 20 years, study shows

Male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm, according to a new study in rodents in the open-access journal PLOS Biology by Eoin Whelan of the School of Veterinary Medicine, University of Pennsylvania and colleagues publishing May 10th.

10 May 2022

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

An important link has been found between the intellectual disability experienced by children with the rare disease Joubert Syndrome (JS) and defects in the hippocampus.

10 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

Despite the effectiveness of vaccination campaigns worldwide, the threat posed by Covid-19 still exists. First of all, a new SARS-CoV-2 variant could very well emerge that may not respond to current vaccines.

10 May 2022

"Serenity Lounges" reduce stress, anxiety and burnout among nurses, study shows

A new Cedars-Sinai study shows that "Serenity Lounges"–break rooms equipped with massage chairs and other relaxation tools–reduced feelings of stress, anxiety and burnout among nurses.

10 May 2022

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images.

10 May 2022

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease.

10 May 2022

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

UNC School of Medicine Scientists have shown for the first time that postnatal gene therapy may be able to prevent or reverse many deleterious effects of a rare genetic disorder called Pitt-Hopkins syndrome.

10 May 2022

Predictive marker and potential treatment option for IBD discovered

There is an urgent need for new and better treatments for people who suffer from Inflammatory Bowel Disease (IBD), a group of disorders that includes ulcerative colitis and Crohn's disease.

10 May 2022

Study uncovers new regulator of prostate cancer metastasis

A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.

10 May 2022

Exploring simultaneous and sequential COVID-19 vaccine candidate

Researchers developed novel lipid nanoparticle (LNP)-based messenger ribonucleic acid vaccine formulations against three pathogenic coronaviruses.

10 May 2022

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Researchers retrieved the first-ever sequenced spike (S) protein structures of the original Wuhan-Hu 1 SARS-CoV-2 strain, the Alpha, Delta, Delta-plus variants, and Omicron sub-variants BA.1 and BA.2 and compared their structural and molecular level variations.

10 May 2022

Investigating the role of cyclins and cyclin-dependent kinases in host restriction of SARS-CoV-2 infection

Researchers investigated COVID-19-triggered changes in the levels of cyclins and cyclin-dependent kinases inside host cells.

10 May 2022

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

B Cell News and Research

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Cells do a little cleanup before mitosis

Testicular tissue can be successfully frozen for over 20 years, study shows

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

Tumors release lactate to force neighboring cells into supporting cancer growth

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

"Serenity Lounges" reduce stress, anxiety and burnout among nurses, study shows

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

Predictive marker and potential treatment option for IBD discovered

Study uncovers new regulator of prostate cancer metastasis

Exploring simultaneous and sequential COVID-19 vaccine candidate

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Investigating the role of cyclins and cyclin-dependent kinases in host restriction of SARS-CoV-2 infection

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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