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Immunogenicity and safety of human papillomavirus vaccine in healthy boys

New industry-supported research from Finland suggests that Cervarix, an HPV vaccine given to girls in Europe and elsewhere, is safe for boys as well.

21 Dec 2008

AstraZeneca submits sNDA for NEXIUM (esomeprazole magnesium)

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for NEXIUM(R) (esomeprazole magnesium) to seek approval for the short-term (up to 6 weeks) treatment of gastroesophageal reflux disease (GERD) in pediatric patients ages 0 to 1 year old.

21 Dec 2008

Smoking during the first trimester of pregnancy linked to oral clefts

Smoking during the first trimester of pregnancy is clearly linked with an increased risk of cleft lip in newborns.

18 Dec 2008

Dieting may help reduce the risk of gum disease, mostly in men

For men, especially older men, dieting may help reduce the risk of gum disease more than for women, according to a new study by researchers at the University of Maryland, Baltimore and other institutions.

17 Dec 2008

Preventing food allergies in children - a change of strategy?

According to the Centers for Disease Control and Prevention (CDC) in the United States in 2007 around 3 million children under 18 had food allergies - a rise of 18% since 1997.

17 Dec 2008

Researchers hunt for new drugs for Leishmaniasis

Hundreds of millions of people, mainly in developing countries, are disabled by infectious diseases, according to the World Health Organization.

16 Dec 2008

Genes involved in antibiotic resistance vary within a species

The recent emergence of multidrug resistance (MDR) in Acinetobacter baumannii, a bacteria that causes infections primarily among seriously ill patients in the intensive care unit who may have reduced immune systems, has raised concern in health care settings worldwide.

16 Dec 2008

Study of placenta unexpectedly leads to cancer gene

University of Rochester Medical Center scientists discovered a gene mutation that impairs the placenta and also is influential in cancer development, according to a study published online December 16, 2008, in the journal PLoS (Public Library of Science) Biology.

16 Dec 2008

New bone and tissue regeneration technique

Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues.

15 Dec 2008

Discovery of link between inflamed gums and heart disease

The next person who reminds you to floss might be your cardiologist instead of your dentist. Scientists have known for some time that a protein associated with inflammation (called C-reactive protein) is elevated in people who are at risk for heart disease.

15 Dec 2008

Tongue reconstruction at University of Michigan

The night before her surgery for tongue cancer, 30-year-old Lisa Bourdon-Krause realized she might never be able to speak to her toddler son again. So she sat up half the night recording messages to him: "Hi, how was your day?," "You're so handsome," "You have a stinky butt. I need to change you." She read two of his favorite books.

15 Dec 2008

Paliperidone palmitate shows positive results for treatment of schizophrenia

Paliperidone palmitate, an investigational long-acting therapy (LAT) demonstrated statistically significant symptom control compared with placebo according to the results of a 13-week study.

14 Dec 2008

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

New data released demonstrates that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.

14 Dec 2008

GlaxoSmithKline statement on FDA advisory committee vote on use of asthma medicines containing long-acting beta agonists

The following is GlaxoSmithKline's statement regarding recommendations of a combined Advisory Committee to the FDA on the use of asthma medicines containing long-acting beta agonists, including GSK's Serevent (salmeterol) and Advair (salmeterol/fluticasone proprionate).

14 Dec 2008

Femara shows reduced risk of death versus tamoxifen after breast cancer surgery

Femara showed reduced risk of death by 13% (P=0.08) versus tamoxifen, despite inclusion of patients who had switched over from tamoxifen to Femara during the study period, following the study's unblinding.

14 Dec 2008

FDA to review Barr Pharmaceutical's BLA for adenovirus type 4 and 7 live oral vaccines

Barr Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has accepted for review Duramed Pharmaceuticals, Inc.'s Adenovirus Types 4 and 7 Live Oral Vaccines Biologics License Application (BLA).

14 Dec 2008

Humble toothbrush helps stop ventilator-associated pneumonia

Hospital-borne infections are a serious risk of a long-term hospital stay, and ventilator-associated pneumonia (VAP), a lung infection that develops in about 15% of all people who are ventilated, is among the most dangerous.

12 Dec 2008

Gene therapy used to treat periodontal disease

Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults.

12 Dec 2008

$Proteolix announces positive data for carfilzomib in patients with relapsed and refractory multiple myeloma$

Proteolix announces positive data for carfilzomib in patients with relapsed and refractory multiple myeloma

Proteolix, Inc. today announced positive clinical data demonstrating that the company's lead product, carfilzomib, has single-agent activity and promotes durable responses in patients with relapsed and refractory multiple myeloma.

10 Dec 2008