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Connective tissue protein promotes immune responses that fight bacterial infections

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study finds.

28 Jun 2021

Novel approach to molecular drug design paves way for promising bladder cancer therapy

A new approach to molecular drug design has yielded a highly promising bladder cancer drug, which induced rapid shedding of tumor cells and resulted in a significant reduction in tumour size when used in clinical trials.

28 Jun 2021

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Experts estimate more than 6 million Americans are living with Alzheimer's dementia. But a recent study, led by the University of Cincinnati, sheds new light on the disease and a highly debated new drug therapy.

28 Jun 2021

Scientists develop a simple, noninvasive diagnostic solution for Alzheimer's disease

An international research team led by HKUST has developed a simple but robust blood test from Chinese patient data for early detection and screening of Alzheimer's disease (AD) for the first time, with an accuracy level of over 96%.

28 Jun 2021

IR imaging-based AI offers a label-free and automated approach to identify lung tumor types

Infrared spectroscopy can automatically distinguish between various types of lung cancer and genetic mutations, allowing quick and reliable statements to be made regarding prognosis and treatment decisions.

28 Jun 2021

Sunflower peptide identified as a potential drug for treating abdominal pain

A naturally occurring peptide in sunflower seeds was synthetically optimised and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area and/or internal organs).

28 Jun 2021

New analysis links distinct patterns of genetic mutations with OCD

In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans.

28 Jun 2021

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Scientists at The University of Toledo discovered new movement in sperm that provides innovative avenues for diagnostics and therapeutic strategies for male infertility.

28 Jun 2021

Study finds minimal SARS-CoV-2 viral load in vaginal secretions

The virus has also been observed to be present in blood, urine, feces, and tears, though not in semen. Vaginal secretions have not been consistently shown to be positive for the virus in most studies. The authors of a new study in the Journal of Clinical Medicine affirm that the presence of the virus in the vagina is rare, irrespective of pregnancy.

28 Jun 2021

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Mutation-signature–associated metrics predict cancer progression in patients

Oncotarget published "Predicting clinical outcomes using cancer progression associated signatures" which reported somatic mutation signatures are an informative facet of cancer etiology, however they are rarely useful for predicting patient outcome.

28 Jun 2021

Tocilizumab and sarilumab shown to be effective in critical COVID-19

A new study, released as a preprint on the medRxiv* server, describes how a team of researchers from the University Medical Center Utrecht in the Netherlands explored the efficacy of four monoclonal antibodies that antagonize powerful pro-inflammatory pathways. The team sought to determine which were useful in treating critically ill COVID-19 patients on organ support.

28 Jun 2021

Oxford-AstraZeneca COVID-19 vaccine induces robust T cell-based immunity

A recent study conducted by an international team of scientists has revealed that the Oxford-AstraZeneca coronavirus disease 2019 (COVID-19) vaccine, AZD1222, is capable of inducing strong spike-specific CD4+ T cell helper type 1 (Th1) and CD8+ T-cell responses in vaccinated individuals. A detailed description of AZD1222-induced cellular immunity is currently available on the medRxiv* preprint server.

28 Jun 2021

Why SARS-CoV-2 delta variant is more infectious

German experts recently explained why the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant is more infectious and pathogenic than its ancestor. By conducting a series of in vitro experiments, they have revealed that increased ability to induce cell-to-cell fusion (syncytia) and reduced susceptibility to vaccine and infection-induced antibodies make the delta variant more infectious than previously circulating variants. The study is currently available on the bioRxiv* preprint server.

28 Jun 2021

Protein C News and Research

Connective tissue protein promotes immune responses that fight bacterial infections

Novel approach to molecular drug design paves way for promising bladder cancer therapy

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Scientists develop a simple, noninvasive diagnostic solution for Alzheimer's disease

IR imaging-based AI offers a label-free and automated approach to identify lung tumor types

Sunflower peptide identified as a potential drug for treating abdominal pain

New analysis links distinct patterns of genetic mutations with OCD

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Study finds minimal SARS-CoV-2 viral load in vaginal secretions

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Mutation-signature–associated metrics predict cancer progression in patients

Tocilizumab and sarilumab shown to be effective in critical COVID-19

Oxford-AstraZeneca COVID-19 vaccine induces robust T cell-based immunity

Why SARS-CoV-2 delta variant is more infectious

Swedish study reveals how long immunity lasts after mild COVID

Oxford study sheds light on level of antibodies needed to protect against COVID-19 symptoms

Lambda lineage of SARS-CoV-2 has potential to become variant of concern

Black Lives Matter Fellowship established to help Black students excel in neuroscience or neurosurgery

Structural studies of SARS-CoV-2 spike protein reveal new properties of Alpha and Beta variants

Research shows how circadian control of glucose production is disrupted during lung cancer progression

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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