Malignant News and Research

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Statistical modeling technique helps track tumor cell diversity

Cancer cells are a wily adversary. One reason the disease outfoxes many potential treatments is because of the diversity of the cancer cell population. Researchers have found this population difficult to characterize and quantify.

20 Feb 2020

Single gene cluster loss promotes initiation and progression of multiple myeloma in mice

The loss of one copy of the miR15a/miR16-1 gene cluster promoted initiation and progression of multiple myeloma in mice.

20 Feb 2020

Study finds wide state-by-state variation in melanoma rates caused by ultraviolet radiation

A new study finds a wide state-by-state variation in rates of melanoma caused by ultraviolet (UV) exposure with highest rates in several states on the East and West Coast including Hawaii, but also a few landlocked states, including Utah, Vermont, and Minnesota.

17 Feb 2020

Autophagy genes work against tumors in some ovarian cancers

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina and University of California at San Diego published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.

13 Feb 2020

Using synthetic cell scaffolds to replace animal testing in cancer research

In the field of cancer research, the idea that scientists can disrupt cancer growth by changing the environment in which cancerous cells divide is growing in popularity. The primary way researchers have tested this theory is to conduct experiments using animals.

11 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

New method to treat cancer with iron oxide nanoparticles

The concept is based on the interaction of resonant semiconductor iron oxide Fe2O3 nanoparticles with light. Particles previously loaded with the antitumor drug are injected in vivo and further accumulate at the tumor areas.

10 Feb 2020

Purdue-developed 'fluorescent markers' begin Phase 3 clinical trials

On Target Laboratories Inc., a privately held biotechnology company developing the use of Purdue University-discovered fluorescent markers to target and illuminate cancer during surgery, has announced the results of a multi-institutional Phase 2 clinical trial in which outcomes were improved for 26% of patients undergoing pulmonary resection for non-small-cell lung cancer.

6 Feb 2020

First comprehensive survey of viruses found within different cancers

Researchers from the University of East Anglia have helped to carry out the first comprehensive survey of viruses found within different types of cancer.

5 Feb 2020

Cancer mutations may arise decades before diagnosis

Researchers at EMBL's European Bioinformatics Institute and the Francis Crick Institute have analyzed the whole genomes of over 2600 tumors from 38 different cancer types to determine the chronology of genomic changes during cancer development.

5 Feb 2020

BACH1 gene regulator facilitates pancreatic cancer metastasis

A multidisciplinary team of researchers at Japan's Tohoku University has found that a gene regulator, called BACH1, facilitates the spread of pancreatic cancer to other parts of the body.

4 Feb 2020

Novel approach may offer a more effective way to eradicate colorectal cancer cells

A novel approach to reverse the progression of healthy cells to malignant ones may offer a more effective way to eradicate colorectal cancer cells with far fewer side effects, according to a team of researchers based in South Korea.

3 Feb 2020

New MRI tool can distinguish between malignant and benign ovarian cysts with 90% accuracy

Researchers have developed a new MRI tool that can identify cases of ovarian cancer which are difficult to diagnose using standard methods.

30 Jan 2020

New research could lead to 'breakthrough' for myelodysplastic syndrome

Korean researchers have observed cup-shaped red blood cells in the peripheral blood of a patient with myelodysplastic syndrome.

From Tomocube Inc. 30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

Researchers develop new strategy to study childhood brain tumors

Researchers are at work to find effective treatments to help young patients with brain tumors. Hundreds of brain organoids have been developed in the laboratories of the University of Trento to understand the genetic mechanisms responsible for these hard to treat diseases.

29 Jan 2020

Study advances the understanding of capillary regression

Many diseases arise from abnormalities in our capillaries, tiny exquisitely branching blood vessel networks that play a critical role in tissue health.

29 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria.

28 Jan 2020

Holistic and data-driven health assessment can help achieve early disease detection

Human Longevity, Inc., an innovator in providing data-driven health intelligence and precision health to physicians and patients, announced today the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences.

27 Jan 2020

Malignant News and Research

Statistical modeling technique helps track tumor cell diversity

Single gene cluster loss promotes initiation and progression of multiple myeloma in mice

Study finds wide state-by-state variation in melanoma rates caused by ultraviolet radiation

Autophagy genes work against tumors in some ovarian cancers

Using synthetic cell scaffolds to replace animal testing in cancer research

Finding a cure for canine gliomas may help find treatment for human brain cancer

New method to treat cancer with iron oxide nanoparticles

Purdue-developed 'fluorescent markers' begin Phase 3 clinical trials

First comprehensive survey of viruses found within different cancers

Cancer mutations may arise decades before diagnosis

BACH1 gene regulator facilitates pancreatic cancer metastasis

Novel approach may offer a more effective way to eradicate colorectal cancer cells

New MRI tool can distinguish between malignant and benign ovarian cysts with 90% accuracy

New research could lead to 'breakthrough' for myelodysplastic syndrome

New target protein linked to regulation, movement of tumor-associated macrophages

Researchers develop new strategy to study childhood brain tumors

Study advances the understanding of capillary regression

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

Holistic and data-driven health assessment can help achieve early disease detection

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