Malignant News and Research

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AI may help eliminate use of biopsy for brain cancer patients

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

21 Apr 2020

Greater occurrence of infections correlates with future cancer diagnosis

Patients experienced a greater occurrence of infections in the years preceding a cancer diagnosis.

17 Apr 2020

Experimental drug could stop tumor relapse, mice study shows

A drug that is well-tolerated in patients and prevents cancer coming back in mice has been identified by researchers at the Francis Crick Institute.

14 Apr 2020

Researchers develop a unique radiochemical synthesis approach for treating cancer

Radiolabeled molecules, so-called radiotracers, help nuclear physicians to detect and precisely target tumors, which are often developing due to pathological changes in metabolic processes.

7 Apr 2020

Hereditary genetic defect linked to medulloblastoma destabilizes protein regulation

The causes of 40 percent of all cases of certain medulloblastoma - dangerous brain tumors affecting children - are hereditary.

1 Apr 2020

Understanding hereditary medulloblastomas in children

This is a combined press release between EMBL, the Hopp Children's Cancer Center Heidelberg and the German Cancer Consortium.

1 Apr 2020

Inherited gene mutation can predispose children to SHH medulloblastoma

Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric medulloblastoma.

1 Apr 2020

New type of immunotherapy shows promise for future treatment of ovarian cancer

Malignant ovarian cancer is insidious: Known and feared for vague and uncharacteristic symptoms that often mean the disease is discovered so late that on average only four out of six patients are still alive after five years.

26 Mar 2020

New handheld, high-resolution medical imaging device has potential for bedside scanning

Scientists at Nanyang Technological University, Singapore have developed the prototype of a handheld medical imaging device that can produce images down to resolutions of 1 to 2 micrometers.

25 Mar 2020

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers.

25 Mar 2020

Study provides better understanding of how dangerous cancer metastases arise

In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche'.

23 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Novel MRI contrast agent for early detection of brain metastases

A group of researchers led by Leif Schroeder from the Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent.

19 Mar 2020

Bacteria-trapping protein may contribute to breast cancer metastasis

The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer Research, a journal of the American Association for Cancer Research.

19 Mar 2020

African-American men less likely to use more targeted biopsy option for prostate cancer

Researchers at the University of Cincinnati have found in a retrospective study that African-American men are less likely to use a more targeted biopsy option for prostate cancer, despite an increased incidence in this group of patients.

17 Mar 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Understanding how cancer cells interact and collaborate to metastasize

Cancer cells are known to migrate and collaborate to form networks that function as conduits providing access to nutrients and blood vessels.

12 Mar 2020

Exploiting careless cancer cells to develop new drugs

Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? Researchers at Uppsala University have succeeded in developing a substance that has demonstrated promising results in experiments on both animal models and human cancer cells.

11 Mar 2020

Inherited ventricular arrhythmia fairly common among Finnish Leonbergers

A new study in Finland has revealed that inherited malignant ventricular arrhythmia is fairly common among Finnish Leonbergers under three years of age. At its worst, such arrhythmia can result in the dog's sudden death.

10 Mar 2020

Malignant News and Research

AI may help eliminate use of biopsy for brain cancer patients

Greater occurrence of infections correlates with future cancer diagnosis

Experimental drug could stop tumor relapse, mice study shows

Researchers develop a unique radiochemical synthesis approach for treating cancer

Hereditary genetic defect linked to medulloblastoma destabilizes protein regulation

Understanding hereditary medulloblastomas in children

Inherited gene mutation can predispose children to SHH medulloblastoma

New type of immunotherapy shows promise for future treatment of ovarian cancer

New handheld, high-resolution medical imaging device has potential for bedside scanning

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Study provides better understanding of how dangerous cancer metastases arise

Immunotherapy treatment shows promise for some patients with advanced rare cancers

Novel MRI contrast agent for early detection of brain metastases

Bacteria-trapping protein may contribute to breast cancer metastasis

African-American men less likely to use more targeted biopsy option for prostate cancer

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Prize-winning research offers a promising approach to improve regenerative medicine

Understanding how cancer cells interact and collaborate to metastasize

Exploiting careless cancer cells to develop new drugs

Inherited ventricular arrhythmia fairly common among Finnish Leonbergers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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