Microscopy News and Research

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Pocket feature in SARS-CoV-2 spike protein is present in all deadly coronaviruses, study reveals

Scientists have discovered why some coronaviruses are more likely to cause severe disease, which has remained a mystery, until now.

24 Nov 2022

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes – potentially paving the way for better and less toxic cancer drugs.

23 Nov 2022

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Researchers performed in vitro experiments to test the ability of different frequencies of ultrasound to inactivate SARS-CoV-2.

23 Nov 2022

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Researchers mapped spatial, cellular, and molecular interactions of host and tumor-associated bacteria within the tumor microenvironment.

22 Nov 2022

Scientists provide metrics for organ development

Organs in the human body have complex networks of fluid-filled tubes and loops. They come in different shapes and their three-dimensional structures are differently connected to each other, depending on the organ.

21 Nov 2022

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Researchers identified β-cyclodextrins (β-CDs) as a safe and cost-effective drug against SARS-CoV-2 with a broad spectrum of activity.

18 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

Researchers explored the efficiency of a macrocyclic peptide in inhibiting the SARS-CoV-2 spike protein.

17 Nov 2022

Bruker announces acquisition of Inscopix for neuroscience research

Bruker Corporation today announced the acquisition of Inscopix, Inc., a neuroscience pioneer and market leader of miniaturized microscopes, known as miniscopes, for freely moving animal brain imaging.

From Bruker Nano Surfaces and Metrology 16 Nov 2022

Research sheds light on cardiac pathology mechanisms of COVID-19

Researchers compared cardiac autopsy samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases with age-matched samples from influenza hemagglutinin 1 neuraminidase 1 (H1N1) cases, non-influenza lymphocytic myocarditis cases, and heart tissue with no inflammation to understand the mechanisms underlying the pathology of the cardiac complications during coronavirus disease 2019 (COVID-19).

15 Nov 2022

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs) against influenza A viruses.

15 Nov 2022

Researchers develop a new method to map the spatial evolution of cancers

Researchers developed a genetic clone mapping workflow centered around base-specific in situ sequencing (BaSISS) technology to derive quantitative maps of multiple genetic clones of cancer cells.

11 Nov 2022

Researchers discover residual tumor cells responsible for colon cancer relapse

Colon cancer is the third most common cancer in the world, with about 2 million new cases each year. Most patients are diagnosed when the tumor is still located in the colon or rectum.

9 Nov 2022

New tool maps how breast cancer grows in previously unseen detail

New technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as mutations in tumor growth.

9 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Microscopy News and Research

Pocket feature in SARS-CoV-2 spike protein is present in all deadly coronaviruses, study reveals

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Scientists provide metrics for organ development

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

Bruker announces acquisition of Inscopix for neuroscience research

Research sheds light on cardiac pathology mechanisms of COVID-19

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Researchers develop a new method to map the spatial evolution of cancers

Researchers discover residual tumor cells responsible for colon cancer relapse

New tool maps how breast cancer grows in previously unseen detail

Scientists determine 5,072 essential human genes

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Scientists uncover a key property needed for CELMoD drugs to be effective

Vimentin is an important co-receptor for SARS-CoV-2 infection

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo