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Republican Convention, Day 4: Fireworks … and shining a light on Trump’s claims

President Donald Trump accepted the Republican Party's nomination for president in a 70-minute speech from the South Lawn of the White House on Thursday night.

28 Aug 2020

New method can help develop drugs that target membrane proteins

Portland State University researchers used advanced electron microscopy to create a 3-D reconstruction of a membrane protein at an unprecedented level of resolution, setting the stage for the development of drugs that could target the protein more effectively to treat a variety of diseases.

28 Aug 2020

Combinations of lipid-lowering therapies could reduce health risk for European patients

New findings from a large European study of patients in 18 countries, including the UK, show that while many patients are able to reduce their risk through taking statins, those at the highest risk of cardiovascular events may benefit from combinations of lipid-lowering therapies.

28 Aug 2020

High blood pressure can be treated without causing erectile dysfunction, shows study

Men with untreated high blood pressure have poorer penile blood flow than those with normal blood pressure, according to research presented today at ESC Congress 2020.1 The differences disappeared with blood pressure medication.

28 Aug 2020

Engineers develop better understanding of skin damage caused by rubbing

Understanding the skin damage caused by rubbing could lead to better topical skin treatments and help prevent the formation of new routes for viral and bacterial infection.

28 Aug 2020

Manipulating 3D Printed Organoid Microenvironments

Organoids are 3-dimensional (3D) clusters of stem cells that come together and emulate the microenvironment within individual organs, whether that be liver, kidney, heart, gut or other specific organs.

From Manchester BIOGEL 28 Aug 2020

New algorithm can help spot illicit online pharmacies

Consumers are expected to spend more than $100 billion at online pharmacies in the next few years, but not all of these businesses are legitimate.

28 Aug 2020

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

WHO and partner organizations call for massive scale-up in investment in mental health

Mental health is one of the most neglected areas of public health. Close to 1 billion people are living with a mental disorder, 3 million people die every year from the harmful use of alcohol and one person dies every 40 seconds by suicide.

28 Aug 2020

FDA continues to take action in the ongoing response to COVID-19 pandemic

The U.S. Food and Drug Administration (FDA) today continued to take action in the ongoing response to the COVID-19 pandemic

28 Aug 2020

SARS discovery boots search for COVID-19 drugs

An extensive search and testing of current drugs and drug-like compounds has revealed compounds previously developed to fight SARS might also work against COVID-19.

27 Aug 2020

Study identifies three clinical course variations in patients with acute decompensated cirrhosis

When the body can no longer compensate the gradual failure of the liver caused by liver cirrhosis, there is a high risk of acute decompensated liver cirrhosis.

27 Aug 2020

First lethal mouse model of SARS-CoV-2 developed

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

27 Aug 2020

FDA warns consumers about alcohol-based hand sanitizers packaged in containers

The U.S. Food and Drug Administration (FDA) is warning consumers about alcohol-based hand sanitizers that are being packaged in containers that may appear as food or drinks and may put consumers at risk of serious injury or death if ingested.

27 Aug 2020

Anticoagulation therapy associated with improved survival among COVID-19 patients

Early in the COVID-19 pandemic, Mount Sinai researchers were among the first to show that anticoagulation therapy was associated with improved survival among hospitalized COVID-19 patients

27 Aug 2020

Improved type of PROTAC enhances intracellular accumulation and protein knockdown

Cancer therapies sometimes involve drugs that mediate the breakdown of specific intracellular proteins that participate in cancer formation and proliferation.

27 Aug 2020

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

For patients with non-small cell lung cancers (NSCLC) marked by RET gene fusions, the targeted therapy selpercatinib was well tolerated and achieved durable objective responses, or tumor shrinkage, in the majority of participants in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

27 Aug 2020

Drugs News and Research

Republican Convention, Day 4: Fireworks … and shining a light on Trump’s claims

New method can help develop drugs that target membrane proteins

Combinations of lipid-lowering therapies could reduce health risk for European patients

High blood pressure can be treated without causing erectile dysfunction, shows study

Engineers develop better understanding of skin damage caused by rubbing

Manipulating 3D Printed Organoid Microenvironments

New algorithm can help spot illicit online pharmacies

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

WHO and partner organizations call for massive scale-up in investment in mental health

FDA continues to take action in the ongoing response to COVID-19 pandemic

SARS discovery boots search for COVID-19 drugs

Study identifies three clinical course variations in patients with acute decompensated cirrhosis

First lethal mouse model of SARS-CoV-2 developed

FDA warns consumers about alcohol-based hand sanitizers packaged in containers

Anticoagulation therapy associated with improved survival among COVID-19 patients

Improved type of PROTAC enhances intracellular accumulation and protein knockdown

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

New approach to combination drug design could be applied to disease therapies beyond diabetes

New COVID-19 antigen test can be directly read from the testing card

Study: Blocking nerve signals to the pancreas could stop patients from developing type 1 diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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