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New insights into multiple myeloma research

Scientists have unveiled the most comprehensive picture to date of the full genetic blueprint of multiple myeloma, a form of blood cancer. A study of the genomes from 38 cancer samples has yielded new and unexpected insights into the events that lead to this form of cancer and could influence the direction of multiple myeloma research.

24 Mar 2011

Researchers create new computational model to understand animal cell behavior

Biological systems, including cells, tissues and organs, can function properly only when their parts are working in harmony. These systems are often dauntingly complex: Inside a single cell, thousands of proteins interact with each other to determine how the cell will develop and respond to its environment.

24 Mar 2011

Sequencing mouse cancer genome reveals mutations driving cancer in humans

Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse — a mouse.

24 Mar 2011

Brain's pleasure and reward circuitry gets a big boost after a sleepless night

A sleepless night can make us cranky and moody. But a lesser known side effect of sleep deprivation is short-term euphoria, which can potentially lead to poor judgment and addictive behavior, according to new research from the University of California, Berkeley.

24 Mar 2011

Study reveals genetic marker for surviving sepsis

New research in the April issue of Anesthesiology shows for the first time a genetic marker in patients who have a greater likelihood of surviving sepsis.

24 Mar 2011

Zebrafish model of human melanoma reveals new cancer gene

Looking at the dark stripes on the tiny zebrafish you might not expect that they hold a potentially important clue for discovering a treatment for the deadly skin disease melanoma. Yet melanocytes, the same cells that are are responsible for the pigmentation of zebrafish stripes and for human skin color, are also where melanoma originates.

24 Mar 2011

Physicians launch international advocacy campaign on TB

Physicians across the globe are coming together to advocate for a large, underrepresented patient population - those suffering from tuberculosis. On World TB Day, March 24th, a team of physician and researchers led by Case Western Reserve University School of Medicine's Tuberculosis Research Unit will nationally launch "I am TB," an international advocacy campaign aimed at reducing stigma among patients with TB and those at risk for the disease.

24 Mar 2011

Fudan, UTHealth introduce international network to fight against scleroderma

Scleroderma clinicians and researchers in the United States and China have launched an international network to fight this debilitating disease that affects more than one million people worldwide.

24 Mar 2011

Scientists reveal protein target that can trigger myocarditis

People with type 1 diabetes, whose insulin-producing cells have been destroyed by the body's own immune system, are particularly vulnerable to a form of inflammatory heart disease caused by a different autoimmune reaction.

24 Mar 2011

U-M professors recommend certain steps to reach research equipoise

In 1998, a study linking the measles, mumps and rubella vaccine to autism in children appeared in a respected medical journal. For a decade, the study grabbed headlines worldwide.

23 Mar 2011

ViroPharma presents Cinryze data against HAE at AAAAI Annual Meeting

ViroPharma Incorporated today announced data presented in two poster presentations relating to Cinryze at the 2011 American Academy of Allergy Asthma & Immunology Annual Meeting, March 18 through 22, in San Francisco, CA.

23 Mar 2011

AHA to honor BIDMC investigator for groundbreaking Vascular Biology research

Alterations in blood vessel dilation lie at the heart of coronary artery health: When vessels dilate, blood and oxygen supplies successfully reach the heart. When vessels contract, blood and oxygen are diminished, leading to coronary artery disease.

23 Mar 2011

Medical oncologist to receive AACR award for breast cancer research

Vassiliki Karantza, MD, PhD, a medical oncologist at The Cancer Institute of New Jersey will be honored with the Genentech BioOncology Career Development Award sponsored by the American Association for Cancer Research at the Association's 102nd Annual Meeting taking place April 2 through 6 in Orlando.

23 Mar 2011

WMU receives $100 million cash gift for new medical school

A $100 million cash gift, the largest ever made to a Michigan college or university, will be used to give birth to a private medical school at a public institution--Western Michigan University.

23 Mar 2011

Oral desensitization with omalizumab may treat milk allergy in children

Some 3 million children in the United States have some form of food allergy, ranging in severity from mild to life-threatening. Milk allergy is the most common, affecting 2.5 percent of children under age 3.

22 Mar 2011

Study: Stem cell transplant may benefit patients with rapidly progressive MS

A long term study reports about the effectiveness of replacing bone marrow, purposely destroyed by chemotherapy, with autologous stem cell rescue for people with aggressive forms of multiple sclerosis.

22 Mar 2011

New research: Trauma patients treated on weekends have greater chance of survival

Patients who've been hurt in car or bike crashes, been shot or stabbed, or suffered other injuries are more likely to live if they arrive at the hospital on the weekend than during the week, according to new University of Pennsylvania School of Medicine research published in the March 21 issue of Archives of Surgery.

22 Mar 2011

Study unravels molecular mechanism of biomolecule RNA that plays dynamic regulatory role in protein selection

If a big bunch of your brain cells suddenly went rogue and decided to become fat cells, it could cloud your decision-making capacity a bit. Fortunately, early in an organism's development, cells make firm and more-or-less permanent decisions about whether they will live their lives as, say, skin cells, brain cells or, well, fat cells.

21 Mar 2011

NasVax reports positive results from Phase 2a trial of oral immunotherapy for non-alcoholic steatohepatitis

NasVax announces the success of a Phase 2a clinical trial of a new oral immunotherapy for non-alcoholic steatohepatitis (NASH), an inflammatory disease associated with fatty liver disease and the metabolic syndrome.

21 Mar 2011

Elevations in 5 amino acids may signal future disease risk

Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear.

21 Mar 2011