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Inhaled nitric oxide reduces adverse effects of stored blood transfusion in mice

Inhaled nitric oxide reduced the adverse effects of transfusing stored blood in mice, according to a study from the December issue of Anesthesiology. Researchers found that inhaled nitric oxide reduced tissue injury and improved short-term survival in mice that were resuscitated with a stored blood transfusion after hemorrhagic shock.

22 Nov 2012

Scars mark hypertension risk in vesicoureteral reflux

Renal scarring associated with vesicoureteral reflux is a significant risk factor for developing hypertension, shows a study of pediatric patients.

21 Nov 2012

Cryoprecipitate plus tranexamic acid boost war injury survival

Administration of cryoprecipitate and tranexamic acid significantly improves the likelihood of survival among seriously injured patients requiring packed red blood cells, suggest results from MATTERS II.

21 Nov 2012

Pregnant women with mental health disorders face too many barriers to stop smoking

Pregnant women with mental health disorders are facing too many barriers to help them quit smoking during pregnancy despite their willingness to accept support, finds a new study published today (21 November) in BJOG: An International Journal of Obstetrics and Gynaecology.

21 Nov 2012

Emergency obstetric care reduced maternal mortality rates up to 74% in two African projects, MSF reports

According to a new briefing paper from Medecins Sans Frontieres (MSF), access to emergency obstetric care, including ambulance service, could help save the lives of up to three quarters of women who might otherwise die in childbirth, AlertNet reports.

21 Nov 2012

Pfizer, Bristol-Myers Squibb receive EC approval for ELIQUIS to prevent NVAF-related stroke

Bristol-Myers Squibb and Pfizer announced today that the European Commission has approved ELIQUIS (apixaban) for prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors.

21 Nov 2012

New insights into what causes uncontrollable bleeding in hemophilia patients

New insights into what causes uncontrollable bleeding in hemophilia patients are provided in a study published by Cell Press on November 20th in the Biophysical Journal. By revealing that blood clots spread in traveling waves through vessels, the study offers new strategies that could lead to the development of more effective treatments for hemophilia as well as common cardiovascular disorders.

20 Nov 2012

Glycoprotein gene flags up heart disease

The glycosylphosphotidylinositol-anchored membrane glycoprotein CD14 gene significantly predicts cardiovascular mortality in adults aged 65 years or over, research shows.

20 Nov 2012

Appropriators focus quietly on omnibus spending bill

Also in the news, the Senate approves legislation to reauthorize federal research and intervention activities to lower the rate of premature births.

20 Nov 2012

Injured patients with high blood alcohol levels less likely to die in hospitals

Injured patients were less likely to die in the hospital if they had alcohol in their blood, according to a study from the University of Illinois at Chicago School of Public Health -- and the more alcohol, the more likely they were to survive.

20 Nov 2012

MSF clinic helping to reduce maternal mortality in Sierra Leone

Some pregnant women in Sierra Leone, which has one of the highest maternal mortality rates in the world, must travel more than 50 miles for health care services, but a Medecins Sans Frontieres clinic and ambulance service established in a remote region has helped reduce maternal mortality in the area by 61 percent, Al Jazeera reports.

20 Nov 2012

Aradigm’s Lipoquin provides full protection in murine models of pneumonic plague

Scientists from the UK Defence Science and Technology Laboratory (Dstl) report, in a preliminary study, that they have demonstrated that a single dose of Aradigm Corporation's liposomal ciprofloxacin formulation Lipoquin administered 24 hours after exposure to a lethal dose of the bacterium Yersinia pestis provided full protection in a murine model of pneumonic plague.

20 Nov 2012

Uninsured patients could be twice as likely to die after brain cancer surgery

Uninsured patients who undergo surgery to remove a brain tumor could be twice as likely to die in the hospital as those who have the same operation but are privately insured, new Johns Hopkins research suggests. In teaching hospitals, where most neurosurgical procedures take place, those with government-subsidized insurance in the form of Medicaid were found in the same study to have rates of survival closer to those who are privately insured.

20 Nov 2012

Most African countries not on track to achieve MDGs, U.N. officials say

"Most African countries are lagging behind in achieving the United Nations' Millennium Development Goals [MDGs] and will not make as much progress in health, nutrition and sanitation as had hoped, U.N. officials said" on Thursday, the Associated Press/ABC News reports.

20 Nov 2012

Addition of tomosynthesis to standard mammogram increases breast screening accuracy

The addition of three-dimensional breast imaging-a technology called tomosynthesis-to standard digital mammography significantly increases radiologists' diagnostic accuracy while reducing false positive recall rates, according to the results of a multi-center study published in Radiology.

20 Nov 2012

World Toilet Day aims to break taboos, encourage construction of clean toilets

World Toilet Day, recognized annually on November 19, "aims to break the taboo around loos and basic hygiene," the Guardian reports. The newspaper continues, "Some 57 countries are seriously off-track to meet the target within Millennium Development Goal [MDG] seven to halve by 2015 the proportion of people without access to basic sanitation; around 2.5 billion people lack access to a clean toilet."

20 Nov 2012

Smoking less a valid risk reduction strategy, says researcher

Countless studies demonstrate the virtues of complete smoking cessation, including a lowered risk of disease, increased life expectancy, and an improved quality of life. But health professionals acknowledge that quitting altogether can be a long and difficult road, and only a small percentage succeed.

20 Nov 2012

Young relatives of sudden cardiac death individuals at high heart disease risk

Young first- and second-degree relatives of individuals who were victims of sudden cardiac death are at a significantly increased risk for developing cardiovascular disease, research suggests.

19 Nov 2012

Research roundup: Talking to patients about end-of-life care

Each week, KHN reporter Alvin Tran compiles a selection of recently released health policy studies and briefs.

17 Nov 2012

ACS Surgical Health Care Quality Forum New York focuses on methods to improve patient safety

Today the American College of Surgeons held the ACS Surgical Health Care Quality Forum New York, the 10th program in a series of events to drive national discussions on effective quality improvement methods that surgeons, physicians and hospitals are using to improve patient safety and reduce costs.

17 Nov 2012