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The Marlene and Spencer Hays Foundation awards $68,000 grant to COMBINEDBrain

Established in 2019 in Nashville, COMBINEDBrain is a non-profit consortium of patient advocacy groups, researchers and clinicians working together to fast-track cures and therapies for individuals afflicted with rare genetic neurodevelopmental disorders.

13 Jan 2021

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Glioblastoma brain tumors are especially perplexing. Inevitably lethal, the tumors occasionally respond to new immunotherapies after they've grown back, enabling up to 20% of patients to live well beyond predicted survival times.

13 Jan 2021

Scientists identify bacteria-based approach against cancer

The body's immune system is the first line of defense against infections like bacteria, viruses or cancers. Some cancers, however, have developed the art of molecular deception to avoid destruction by the body's immune system.

13 Jan 2021

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood around the body as it contracts).

13 Jan 2021

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

Thanks to major progress in the understanding and management of rare congenital diseases and syndromes, many patients with these rare disorders are now living longer lives.

13 Jan 2021

Medical institutions should support health care workers with COVID-19 infection, say experts

By mid-November, the Centers for Disease Control and Prevention had reported that 218,439 health care workers in the U.S. had been infected with COVID-19 -- a likely underestimate due to incomplete data from states.

13 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Scientists determine ideal dose of stem cells to control HIV

Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife.

12 Jan 2021

Robotic device powered by patients’ own brains helps improve stroke rehabilitation

Stroke survivors who had ceased to benefit from conventional rehabilitation gained clinically significant arm movement and control by using an external robotic device powered by the patients' own brains.

12 Jan 2021

Stimulation method helps some people with spinal cord injury to regain hand and arm mobility

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can't do everyday tasks such as eating, grooming or drinking water without help.

12 Jan 2021

UW investigators and Talkspace collaborate to study patient experiences with telepsychotherapy

As Americans come to grip with a mental health crisis worsened by the pandemic, smartphone and other digital-health applications are getting more scrutiny.

12 Jan 2021

Boosting a natural cellular process could lower ventilator-related lung damage

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

12 Jan 2021

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published today in the journal Nature Communications.

12 Jan 2021

Researchers study how anorexia nervosa modifies body awareness

People with anorexia nervosa have a distorted relationship with the dimensions of their body. A study by the team at the Clinic for Psychosomatic Medicine and Psychotherapy at LWL University Hospital at Ruhr-Universität Bochum has shown that, in addition to the conscious body image, what is known as the body schema – unconscious body awareness – is also distorted.

12 Jan 2021

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

OXGENE™ announces the introduction of its self-labelling integral membrane (SLIM™) protein discovery system.

12 Jan 2021

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

Researchers identify shorter form of ACE2 that lacks SARS-CoV-2 binding site

A shadow over the promising inhaled interferon beta COVID-19 therapy has been cleared with the discovery that although it appears to increase levels of ACE2 protein - coronavirus' key entry point into nose and lung cells - it predominantly increases levels of a short version of that protein, which the virus cannot bind to.

12 Jan 2021

Researchers study the behavior of regulatory T cells to understand periodontal disease

In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone?

12 Jan 2021

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Indiana University School of Medicine and Regenstrief Institute research scientists have received a $3.4 million award from the Patient-Centered Outcomes Research Institute to investigate the best care options for the 40 percent of people who go to the hospital emergency department with chest pain that is determined to be caused by anxiety rather than a cardiac event.

11 Jan 2021

Therapy News and Research

The Marlene and Spencer Hays Foundation awards $68,000 grant to COMBINEDBrain

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Scientists identify bacteria-based approach against cancer

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

Medical institutions should support health care workers with COVID-19 infection, say experts

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Scientists determine ideal dose of stem cells to control HIV

Robotic device powered by patients’ own brains helps improve stroke rehabilitation

Stimulation method helps some people with spinal cord injury to regain hand and arm mobility

UW investigators and Talkspace collaborate to study patient experiences with telepsychotherapy

Boosting a natural cellular process could lower ventilator-related lung damage

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Researchers study how anorexia nervosa modifies body awareness

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Researchers identify shorter form of ACE2 that lacks SARS-CoV-2 binding site

Researchers study the behavior of regulatory T cells to understand periodontal disease

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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