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Blood vessels use endothelial communication system to control cardiovascular activity, study shows

An invisible lining of blood vessels uses a vast network of connections to control all cardiovascular functions and the risk of developing cardiovascular disease.

5 May 2022

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

In a recent study posted to the Research Square* preprint server, researchers tested the safety and immunogenicity of a third dose of coronavirus disease 2019 (COVID-19) prototype messenger ribonucleic acid (mRNA)-1273 versus a variant vaccine and a bivalent vaccine formulation.

5 May 2022

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases.

4 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

Study offers provable standards for SARS-CoV-2 UVC disinfection

When the COVID-19 pandemic emerged in early 2020, ultraviolet radiation became one of the go-to methods for preventing the spread of the SARS-CoV-2 virus, along with facemasks, hand sanitizer and social distancing.

4 May 2022

New study helps explain the immune system’s response to skin infections and skin cancers

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response.

4 May 2022

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill them.

4 May 2022

Researchers overcome a major hurdle to reverse hearing loss due to aging

Hearing loss due to aging, noise and certain cancer therapy drugs and antibiotics has been irreversible because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells -- essential for hearing – once they die.

4 May 2022

Experts develop new method to control gene expression using electrical signals

Researchers have created an improved method for turning genes on and off using electrical signals.

4 May 2022

People with highest levels of antioxidants less likely to develop dementia, finds study

People with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May 4, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 May 2022

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines

Scientists have discussed the possibilities of developing oral replicon-based mRNA vaccines against SARS-CoV-2.

4 May 2022

The war against COVID-19: reinfection, vaccines, and herd immunity

A communication published in the journal Epidemiologia aimed to answer several questions concerning neutralizing antibodies against SARS-CoV-2, herd immunity, and COVID-19 vaccines.

4 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Researchers determined the threshold neutralizing antibody titer for effective COVID-19 convalescent plasma therapy.

4 May 2022

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

The current study aimed to understand how far this reduced vaccine efficacy and the protection conferred by prior infection in terms of Omicron infection, hospitalization, and oxygen supplementation.

4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022

Newly discovered brain circuit facilitates the ability to focus on what is important in the environment

When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new research from UC San Francisco. The link, originating in the prefrontal cortex and stretching to the hippocampus, provides evidence of how the brain's higher cognitive regions refine operations occurring in distant brain areas.

4 May 2022

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells.

4 May 2022

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer's disease, and a study led by the University of California San Diego provides new evidence to support this claim.

4 May 2022

B Cell News and Research

Blood vessels use endothelial communication system to control cardiovascular activity, study shows

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Study offers provable standards for SARS-CoV-2 UVC disinfection

New study helps explain the immune system’s response to skin infections and skin cancers

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Researchers overcome a major hurdle to reverse hearing loss due to aging

Experts develop new method to control gene expression using electrical signals

People with highest levels of antioxidants less likely to develop dementia, finds study

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines

The war against COVID-19: reinfection, vaccines, and herd immunity

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

Researchers create models to study brain metastases that recapitulate the disease

Researchers reveal the mechanism of action of century-old BCG vaccine

Newly discovered brain circuit facilitates the ability to focus on what is important in the environment

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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