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Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

Activating or deactivating drugs with the help of light

Scientists at the Paul Scherrer Institute PSI have used the Swiss X-ray free-electron laser SwissFEL and the Swiss Light Source SLS to make a film that could give a decisive boost to developing a new type of drug.

20 Feb 2023

395 genes found to be differently expressed in people with type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion.

20 Feb 2023

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through the body.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Mirror neurons for fighting found in mouse hypothalamus

In a recent study published in the journal Cell, researchers utilized a genetically encoded mirror-TRAP strategy to investigate the functional importance of aggression-mirroring neurons.

19 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Cells in the blood such as immune cells, red blood cells and other vital cell types are constantly renewed from stem cells, the so-called hematopoietic stem and progenitor cells (HSPCs).

19 Feb 2023

Toxic protein may be the cause of muscular dystrophy and arhinia

Balancing care responsibilities with paid work provides working caregivers with emotional benefits

19 Feb 2023

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

A new state-of-the-art method that measures the amounts of drugs and lipids (fats) in individual cells could help health professionals target more effective treatments for diseases such as tuberculosis (TB).

17 Feb 2023

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

17 Feb 2023

“Cell food” reveals how different metabolic programs regulate T cell persistence

New research from the University of Michigan Rogel Cancer Center reveals that the metabolic pathways that make a specific type of T cell function are different than previously believed.

17 Feb 2023

Mechanistic insight into how receptor location is the key for psychedelic drug effects

Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells.

17 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Researchers determined the prevalence of antibodies against the SARS-CoV-2 spike glycoprotein following three or more doses of COVID-19 vaccines among immunocompromised individuals.

17 Feb 2023

Beckman Coulter Life Sciences presenting at SLAS2023

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the upcoming Society for Laboratory Automation and Screening (SLAS) International Conference and Exhibition.

From Beckman Coulter Life Sciences 16 Feb 2023

A new trial to assess if butyrate can prevent colon cancer

Researchers discuss a new clinical trial that will determine the efficacy of butyrate administration in preventing colon cancer.

16 Feb 2023

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH) - as well as funding from the U.S. Department of Defense - to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Cell News and Research

Research reveals regional differences in the spread of Japan's two main ancestral groups

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Activating or deactivating drugs with the help of light

395 genes found to be differently expressed in people with type 2 diabetes

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Utilizing CRISPR to discover new therapy options for COPD

Genome editing prevents hypertrophic cardiomyopathy in mice

Mirror neurons for fighting found in mouse hypothalamus

Gut dysbiosis and sepsis susceptibility among pregnant women

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Toxic protein may be the cause of muscular dystrophy and arhinia

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

Ferroptosis could be the key to making effective immunotherapies against liver cancer

“Cell food” reveals how different metabolic programs regulate T cell persistence

Mechanistic insight into how receptor location is the key for psychedelic drug effects

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Beckman Coulter Life Sciences presenting at SLAS2023

A new trial to assess if butyrate can prevent colon cancer

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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