Bone News and Research

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Findings may lead to new drug therapies to reduce breast cancer metastasis

Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer.

4 Nov 2009

Enobia Pharma initiates study of bone-targeted enzyme replacement therapy for hypophosphatasia

Enobia Pharma announced today the initiation of a Phase 2 clinical study of ENB-0040, a bone-targeted enzyme replacement therapy, under investigation for the treatment of hypophosphatasia (HPP). The six-month study will assess the safety, efficacy and pharmacokinetics of ENB-0040 in up to 12 children with HPP.

4 Nov 2009

Breastfeeding: ADA position paper details health benefits for both infants and mothers

The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible.

4 Nov 2009

Stereotactic radiosurgery effectively controls pain in patients with cancer

Stereotactic radiosurgery (SRS), a radiation therapy procedure pioneered at the University of Pittsburgh Cancer Institute (UPCI) that precisely delivers a large dose of radiation to tumors, effectively controls pain in patients with cancer that has spread to the spine, according to researchers from UPCI.

4 Nov 2009

Health Canada approves the marketing of BioMimetic Therapeutics' Augment Bone Graft

BioMimetic Therapeutics, Inc. announced today that it has received approval from Health Canada to begin the marketing of its lead orthopedic product, Augment™ Bone Graft, as an alternative to the use of autograft in midfoot, hindfoot and ankle fusion indications in Canada.

3 Nov 2009

$3.9 million Challenge grant for Thomas Jefferson researchers

Four researchers from Thomas Jefferson University have received $3.9 million in Challenge grant funds as part of the American Recovery and Reinvestment Act.

3 Nov 2009

Arrowhead Research updates its shareholders

Arrowhead Research Corporation’s (NASDAQ: ARWR) President and Chief Executive Officer today issued the following letter to the Company’s shareholders.

3 Nov 2009

Texas State University researchers to evaluate the effects of ALKA-V6 on animal organisms

Texas State University and Orizon Research Institute announced the signing of an agreement today that will permit University Researchers to continue efforts through in vivo testing to further determine the potential and effectiveness of ALKA-V6, a compound which has shown remarkable ability to kill cancer cells and inhibit the HIV virus in laboratory experiments.

3 Nov 2009

Children who drink full-fat milk every day have a lower BMI: Study

Eight-year-old children who drink full-fat milk every day have a lower BMI than those who seldom drink milk. This is not the case for children who often drink medium-fat or low-fat milk. This is one conclusion of a thesis presented at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

3 Nov 2009

Non-invasive treatment is equally effective as surgery for healing the bone, say researchers

When fractured bones fail to heal, a serious complication referred to as "nonunion" can develop. This occurs when the process of bone healing is interrupted or stalled. According to a new study published in the November 2009 issue of The Journal of Bone and Joint Surgery (JBJS), certain cases involving nonunions respond very well to shock-wave therapy. Researchers say this non-invasive treatment is equally effective as surgery when it comes to healing the bone.

3 Nov 2009

Appropriate treatment for children with meniscal tears leads to high success rate: Study

The meniscus is a rubber-like, crescent moon-shaped cartilage cushion that sits between the leg and thigh bone. Each knee has two menisci: one on the inside of the knee joint and one on the outside. In recent years, more children have been diagnosed with tears to this area (meniscal tears); however, according to a literature review published in the November 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), prospects for a full recovery are high.

3 Nov 2009

$Aggressive osteoporosis prevention could reduce hip fracture rate in the U.S. by 25%: Study$

Aggressive osteoporosis prevention could reduce hip fracture rate in the U.S. by 25%: Study

Aggressively managing patients at risk for osteoporosis could reduce the hip fracture rate in the United States by 25 percent, according to a Kaiser Permanente study published in the November issue of the Journal of Bone & Joint Surgery. The first step must be a more active role by orthopedic surgeons in osteoporosis disease management, researchers say.

3 Nov 2009

Interim data from Schering-Plough's narlaprevir Phase IIa study

Schering-Plough Corporation reported that interim results from an ongoing Phase IIa study of narlaprevir (SCH 900518), its investigational, once-daily protease inhibitor, demonstrated potent antiviral activity in treatment-naive patients with chronic hepatitis C virus (HCV) genotype 1.

3 Nov 2009

Therapy with EBV-specific CTLs effective for severely immune-compromised patients

Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection, said a group of researchers led by those from Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital.

3 Nov 2009

$New drug may help bone fractures heal more quickly after radiation exposure$

New drug may help bone fractures heal more quickly after radiation exposure

A drug currently under development by the University of Pittsburgh School of Medicine may help bone fractures heal more quickly after radiation exposure, according to a study by Pitt researchers. The study's results will be presented at 1 p.m. today during the American Society for Radiation Oncology (ASTRO) annual meeting in Chicago.

3 Nov 2009

IMC-RT does not benefit breast cancer patients

After mastectomy, breast cancer patients who receive radiation treatment to the lymph nodes located behind the breast bone do not live longer than those who do not receive radiation to this hard-to-treat area, according to a randomized 10-year study presented at the plenary session, November 2, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).

3 Nov 2009

Seasonal Vitamin D supplement launched by USANA Health Sciences

USANA Health Sciences, Inc. today launched its seasonal Vitamin D supplement. The supplement will be available every year from November to March, the months when many people do not get enough vitamin D.

3 Nov 2009

Cardium Therapeutics to seek FDA marketing clearance for ExcellagenXL

Cardium Therapeutics today announced plans to submit a 510(k) premarket notification with the U.S. Food and Drug Administration (FDA) seeking marketing clearance of its ExcellagenXL(TM) product candidate.

3 Nov 2009

Enzo Biochem announces results of EGS21 clinical trial for treatment of non-alcoholic steatohepatitis

Enzo Biochem Inc. announced today that favorable results of the Company’s clinical trial for treatment of non-alcoholic steatohepatitis (NASH) were presented at the annual meeting of the American Association for the Study of Liver Diseases. The study was a randomized double blind placebo controlled format of EGS21, Enzo’s orally administered beta glucosylceramide formulation, designed to evaluate safety and efficacy of the study drug in patients with NASH and its associated metabolic syndrome.

2 Nov 2009

FDA issues a Complete Response Letter for GTx' toremifene NDA

GTx, Inc. today announced that it has received a Complete Response Letter issued by the United States Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for toremifene 80 mg to reduce fractures in men with prostate cancer receiving androgen deprivation therapy (ADT).

2 Nov 2009

Bone News and Research

Findings may lead to new drug therapies to reduce breast cancer metastasis

Enobia Pharma initiates study of bone-targeted enzyme replacement therapy for hypophosphatasia

Breastfeeding: ADA position paper details health benefits for both infants and mothers

Stereotactic radiosurgery effectively controls pain in patients with cancer

Health Canada approves the marketing of BioMimetic Therapeutics' Augment Bone Graft

$3.9 million Challenge grant for Thomas Jefferson researchers

Arrowhead Research updates its shareholders

Texas State University researchers to evaluate the effects of ALKA-V6 on animal organisms

Children who drink full-fat milk every day have a lower BMI: Study

Non-invasive treatment is equally effective as surgery for healing the bone, say researchers

Appropriate treatment for children with meniscal tears leads to high success rate: Study

Aggressive osteoporosis prevention could reduce hip fracture rate in the U.S. by 25%: Study

Interim data from Schering-Plough's narlaprevir Phase IIa study

Therapy with EBV-specific CTLs effective for severely immune-compromised patients

New drug may help bone fractures heal more quickly after radiation exposure

IMC-RT does not benefit breast cancer patients

Seasonal Vitamin D supplement launched by USANA Health Sciences

Cardium Therapeutics to seek FDA marketing clearance for ExcellagenXL

Enzo Biochem announces results of EGS21 clinical trial for treatment of non-alcoholic steatohepatitis

FDA issues a Complete Response Letter for GTx' toremifene NDA

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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