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Mitochondria regulates stem cell proliferation in gut epithelium, study shows

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich addressed this question by generating a new model system.

27 Oct 2016

Neonate girls present greater antioxidant defense, less oxidative stress than boys

A study carried out by researchers from the University of Granada in collaboration with San Cecilio Clinic Hospital has scientifically proved that neonate girls present a greater antioxidant defense and less oxidative stress on their cell membranes than boys, in addition to higher antioxidant enzymatic activity.

27 Oct 2016

Physically active children in urban areas have high black carbon exposure, study finds

Children from urban areas of New York City who engaged in vigorous daily exercise had greater exposure to black carbon, a traffic-related pollutant, than children who were less active, according to a study by a multidisciplinary team of researchers from Columbia University's College of Physicians & Surgeons and Columbia's Mailman School of Public Health.

26 Oct 2016

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

An experimental drug shows promise in treating Alzheimer's disease by preventing inflammation and removing abnormal protein clumps in the brain that are associated with the disease, suggests a study in mice presented at the ANESTHESIOLOGY 2016 annual meeting.

25 Oct 2016

Exposure to air pollution may contribute to blood vessel damage among young healthy adults

Fine particulate matter air pollution may be associated with blood vessel damage and inflammation among young, healthy adults, according to new research in Circulation Research, an American Heart Association journal.

25 Oct 2016

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, asthma, cancer, diabetes, heart disease and even mental illness.

24 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

Researchers discover new therapeutic target for controlling fatal allergic reactions

Researchers in France have identified a molecular motor that controls the release of inflammatory factors that cause severe and fatal allergic reactions.

24 Oct 2016

International scientists create first 3D atomic-level image of human cannabinoid receptor 1

In a discovery that advances the understanding of how marijuana works in the human body, an international group of scientists, including those from the Florida campus of The Scripps Research Institute (TSRI), have for the first time created a three-dimensional atomic-level image of the molecular structure activated by tetrahydrocannabinol (THC), the active chemical in marijuana.

24 Oct 2016

TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T cells (Treg) to treat severe chronic inflammatory and autoimmune diseases, today announces the signature of a strategic R&D collaboration agreement with the University of British Columbia (UBC) in Vancouver, Canada, a leading global center for multidisciplinary research and teaching.

24 Oct 2016

Status uncertainty may be risk factor for acute diseases, study shows

Having strong social connections has many benefits, from splitting the tab on a pizza to having someone with whom to binge watch Netflix.

21 Oct 2016

Scientists discover new mechanism for inadequate immune defense against chronic viral infection

Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development. They have been published in the journal "Science Immunology".

21 Oct 2016

Researchers suggest benefits of using lasers in oral debridement to prevent dental problems

Researchers have developed computer simulations showing how lasers attack oral bacterial colonies, suggesting that benefits of using lasers in oral debridement include killing bacteria and promoting better dental health.

21 Oct 2016

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit The Cell Factory in collaboration with Women's and Children's Health Department of the University of Padua and the Padua University Hospital are developing therapies for inflammatory bowel disease (IBD) using extracellular vesicles (EVs).

21 Oct 2016

Study sheds new insights on immune cells involved in fighting dengue virus infection

India suffers from the highest number of dengue infections in the world, but there are few studies, if any, to understand the immune cells involved in fighting the virus.

21 Oct 2016

Gut microbes can modify our mood and behaviour, research reveals

If aliens were to examine a human, they would think we were just slavish organisms designed to feed microbes and carry them around.

21 Oct 2016

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

In the first genome-wide association study of genetic risk factors for inflammatory bowel disease in African Americans, a research team has identified two regions of the genome (loci) associated with ulcerative colitis only in people of African descent.

20 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Optical and PET/CT activity-based probes could help in non-invasive imaging of atherosclerotic plaques

Researchers at Stanford University have demonstrated for the first time the use of a dual optical and PET/CT activity-based probe to detect atherosclerotic plaques. The study is published in the October issue of the Journal of Nuclear Medicine.

20 Oct 2016

FDA approves new therapy for initial treatment of soft tissue sarcoma

The U.S. Food and Drug Administration today granted accelerated approval to Lartruvo (olaratumab) with doxorubicin to treat adults with certain types of soft tissue sarcoma (STS), which are cancers that develop in muscles, fat, tendons or other soft tissues.

19 Oct 2016

Inflammation News and Research

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

Neonate girls present greater antioxidant defense, less oxidative stress than boys

Physically active children in urban areas have high black carbon exposure, study finds

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

Exposure to air pollution may contribute to blood vessel damage among young healthy adults

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

New approach could overcome large immunosuppressive tumors

Researchers discover new therapeutic target for controlling fatal allergic reactions

International scientists create first 3D atomic-level image of human cannabinoid receptor 1

TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

Status uncertainty may be risk factor for acute diseases, study shows

Scientists discover new mechanism for inadequate immune defense against chronic viral infection

Researchers suggest benefits of using lasers in oral debridement to prevent dental problems

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Study sheds new insights on immune cells involved in fighting dengue virus infection

Gut microbes can modify our mood and behaviour, research reveals

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Optical and PET/CT activity-based probes could help in non-invasive imaging of atherosclerotic plaques

FDA approves new therapy for initial treatment of soft tissue sarcoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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