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Researchers develop 3D imaging technique to visualize damaged lung tissue after severe COVID-19

Physicists at the University of Göttingen, together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19.

21 Aug 2020

Key molecule can be used to assess prognosis of triple negative breast cancer

Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

AI can expedite drug repurposing process for finding COVID-19 therapies, says GlobalData

Out of all the different approaches available to find new therapies to treat COVID-19, drug repurposing is one of the fastest and safest methods, as the drugs are already being used to treat other conditions therefore leading to fewer chances of adverse reactions.

21 Aug 2020

Avacta expands multi-target collaboration with LG Chem Life Sciences

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce the expansion of its existing multi-target collaboration and development agreement with LG Chem Life Sciences (LG Chem), the life sciences division of the South Korean LG Group, to include new programs incorporating Avacta’s Affimer XT serum half-life extension system.

From Avacta Life Sciences Ltd. 21 Aug 2020

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

A new federally funded study could reveal the nervous system cells and circuits in our brains that influence our metabolism and health in response to dietary changes.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

Whey protein from human breastmilk inhibits SARS-CoV-2 infection

Many scientists have reported the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy and the virus has been detected in breastmilk. Now a new study published on the preprint server bioRxiv* in August 2020 shows that whey protein in human breastmilk efficiently prevents infection with SARS-CoV-2 as well as post-entry viral replication.

20 Aug 2020

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States.

20 Aug 2020

FDA provides update on adverse events associated with breast implants

Today, the U.S. Food and Drug Administration is providing an update on adverse events reported to the Agency related to breast implants, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and systemic signs and symptoms referred to by patients as breast implant illness (BII), which some patients report after receiving breast implants.

20 Aug 2020

KHN’s ‘What the Health?’: Democrats in array (for now)

Democrats have shown a remarkably united front, including on health care, in their socially distant, made-for-TV convention this week.

20 Aug 2020

Study reveals a promising treatment for Parkinson's disease

Scientists at the University Bath in the UK have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson's disease.

20 Aug 2020

Cells lining the nose are key entry point for coronavirus, shows study

Scientists at Johns Hopkins Medicine, experimenting with a small number of human cell samples, report that the "hook" of cells used by SARS-CoV-2 to latch onto and infect cells is up to 700 times more prevalent in the olfactory supporting cells lining the inside of the upper part of the nose than in the lining cells of the rest of the nose and windpipe that leads to the lungs.

20 Aug 2020

Inhibition of key receptor implicated in post-stroke damage and recovery

Many people who suffer a stroke are permanently disabled. Stroke remains the leading cause of long-term disability in the United States.

20 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

Study may lead to new targeted therapies that inhibit the spread of cancer

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream.

20 Aug 2020

Drug used in rheumatoid arthritis and cancer treatment improves survival in critically ill COVID-19 patients

Researchers at Hackensack Meridian Health, New Jersey's largest and most comprehensive health network, have utilized its statewide observational database of more than 5,000 hospitalized COVID-19 patients to show that a drug normally used in rheumatoid arthritis and cancer treatments, tocilizumab, improves hospital survival in critically-ill patients admitted to the intensive care unit (ICU).

20 Aug 2020

New database could speed the development of gene-targeted therapies for breast cancer

All current breast cancer drugs were first tested in cell lines. Each cell line began as cancer in a patient. As such, each cell line is a surrogate for that patient's disease.

19 Aug 2020

Drugs News and Research

Researchers develop 3D imaging technique to visualize damaged lung tissue after severe COVID-19

Key molecule can be used to assess prognosis of triple negative breast cancer

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

AI can expedite drug repurposing process for finding COVID-19 therapies, says GlobalData

Avacta expands multi-target collaboration with LG Chem Life Sciences

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

A metabolic enzyme shows great potential as target for immunotherapies

Whey protein from human breastmilk inhibits SARS-CoV-2 infection

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

FDA provides update on adverse events associated with breast implants

KHN’s ‘What the Health?’: Democrats in array (for now)

Study reveals a promising treatment for Parkinson's disease

Cells lining the nose are key entry point for coronavirus, shows study

Inhibition of key receptor implicated in post-stroke damage and recovery

Researchers develop vaccine for human herpesvirus 6B

Study may lead to new targeted therapies that inhibit the spread of cancer

Drug used in rheumatoid arthritis and cancer treatment improves survival in critically ill COVID-19 patients

New database could speed the development of gene-targeted therapies for breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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