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New research provides clues into development of mammalian cerebral cortex

The cerebral cortex - the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness - has fascinated neuroscientists for centuries.

8 Jun 2018

Study reveals new genetic causes of non-syndromic cleft lip and palate

A study conducted by an international research team, which included investigators from Seattle Children's Research Institute, implicates variants in four genes as a primary cause of non-syndromic cleft lip and palate in humans.

8 Jun 2018

Researchers discover new therapy combination that may help treat ovarian cancer

Researchers at The University of Kansas Cancer Center have discovered a therapy combination that may be helpful in the treatment of certain types of ovarian cancer.

8 Jun 2018

Researchers discover protein responsible for X chromosome inactivation

Researchers have discovered that the structural protein SMCHD1 is required to prevent genes from both X chromosomes being expressed in female mammals.

7 Jun 2018

Study reveals mechanism behind eye loss in blind cavefish

Blind cavefish lose critical eye tissues within a few days after their eyes begin to develop.

7 Jun 2018

Colorado researchers suggest new combination therapy for advanced head and neck cancer

The five-year survival rate for locally-advanced head and neck cancer is only 46 percent, even with treatments including surgery, radiation, chemotherapy and/or genetically targeted treatments such as cetuximab.

7 Jun 2018

New approach to kill specific bacteria could be alternative to antibiotics

A new approach to killing C. difficile that silences key bacterial genes while sparing other bacteria may provide a new way to treat the most common hospital-acquired bacterial infection in the United States, according to researchers.

7 Jun 2018

New cell-based technologies could help improve understanding of muscle-wasting disease

Researchers from Queen Mary University of London have developed new cell-based technologies which could help improve understanding of the muscle-wasting disease Duchenne muscular dystrophy (DMD) and test potential drugs for the disease.

6 Jun 2018

Study finds how colon cancer alters its genes to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

6 Jun 2018

Scientists uncover new way to make cancers sensitive to treatment

Scientists have uncovered a completely new way to make cancers sensitive to treatment - by targeting antenna-like structures on cells.

6 Jun 2018

Researchers develop novel tool to analyze millions of single cells simultaneously

New research led by Holger Heyn at the Centro Nacional de Análisis Genómico of the Centre for Genomic Regulation, presents a sophisticated computational framework to analyze single-cell gene expression levels, scalable to process millions of individual cells.

From 10x Genomics, Inc. 6 Jun 2018

Zebrafish may hold answers to how tumors develop in childhood muscle cancer

A popular aquarium fish may hold answers to how tumors form in a childhood cancer.

6 Jun 2018

Finnish research solves family blood mystery

It's the late 1970s, and a man with an unexplained high hemoglobin level (Hb) is referred to Namsos Hospital north of Trondheim, Norway. It turns out that four members of his family have the same condition. Doctor Kjell Kanelønning is the physician who treats the family.

6 Jun 2018

Researchers explore targeted second-line treatment for colorectal cancer

Targeted therapy with anti-VEGF and anti-EGFR antibodies both improve outcomes when added to chemotherapy in the treatment of colorectal cancer. However, some previous studies suggested the combination of the two antibodies may have a negative interaction.

5 Jun 2018

New way of delivering gene therapy shows promise in treating brain conditions

Researchers from the School of Immunology & Microbial Sciences have engineered a novel way of delivering gene therapy that they hope will mean scientists and doctors can target areas of the brain that were previously difficult to reach.

5 Jun 2018

New findings shed light on biological mechanisms of gene regulation

A team led by Prof. Stein Aerts uncovers how access to relevant DNA regions is orchestrated in epithelial cells.

5 Jun 2018

Scientists shed light on key aspect of healthy cell division

Scientists have shed light on a key aspect of healthy cell division, helping build a clearer picture of the complex mechanisms involved.

5 Jun 2018

Exercise can help overcome genetic effects of obesity in older age

If you're up there in age and feel like you can coast as a couch potato, you may want to reconsider. A new study suggests, for the first time in women over age 70, that working up a sweat can reduce the influence one's genes have on obesity.

5 Jun 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018

New study shows how alcohol contributes to development of Alzheimer's disease

Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta -- the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.

5 Jun 2018