Oral News and Research

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Misoprostol off-label use may have led to deaths

Preliminary U-M studies indicate that oral use of RU-486's companion drug misoprostol is safe, but vaginal use may undermine body's immune responses

16 Jun 2008

Pomegranate extract may provide humans with relief of chronic inflammatory conditions

Oral ingestion of pomegranate extract reduces the production of chemicals that cause inflammation suggests a study published in BioMed Central's open access Journal of Inflammation. The findings indicate that pomegranate extract may provide humans with relief of chronic inflammatory conditions.

15 Jun 2008

Fluoride toothpaste too pricey for world's poorest people

Fluoride toothpaste is prohibitively expensive for the world's poorest people, according to a study published in BioMed Central's open access journal Globalization and Health. Researchers revealed that the poorest populations of developing countries have the least access to affordable toothpaste.

15 Jun 2008

Simple steps can help reduce your risk of contracting potentially deadly superbug

With beach-season looming, the fitness bug is motivating Chicagoans to fill area gyms in droves, all hoping to buff up before the warm-weather season of fun gets into full swing.

11 Jun 2008

High prevalence of periodontal disease in rheumatoid arthritis found

Over 1.3 million Americans suffer from rheumatoid arthritis (RA), a chronic, inflammatory disease of the joints. RA is a disabling condition, and can lead to long-term joint damage resulting in persistent pain and loss of function in affected areas. higher prevalence of periodontal disease in rheumatoid arthritis patients

11 Jun 2008

Having heart surgery? Watch your blood sugar

Nearly half of all heart surgery patients may experience blood sugar levels high enough to require temporary insulin treatment after their operation, even though they've never had diabetes, according to a new study from the University of Michigan Health System.

10 Jun 2008

Specialist nurses can play a key role in supporting patients having radiotherapy, but more investment is needed

Cancer patients who attended a specialist nurse clinic rather than a consultant-led clinic for regular radiotherapy reviews benefited from longer, more frequent consultations and good symptom management, according to a paper in the June issue of the Journal of Clinical Nursing.

10 Jun 2008

FDA grants pediatric exclusivity for UCB's Keppra

UCB has announced that the US Food and Drug Administration (FDA) has granted pediatric exclusivity for Keppra (levetiracetam). The decision was based on pediatric data submitted to the FDA following a written request in 2001.

8 Jun 2008

Boehringer Ingelheim, Gilead to freeze AIDS drug price

AIDS Healthcare Foundation (AHF) today applauded decisions by Boehringer Ingelheim (BI) and Gilead Sciences, Inc. to freeze prices on antiretroviral medications purchased by government agencies.

3 Jun 2008

Paclitaxel Poliglumex/Capecitabine regimen well tolerated and active in metastatic breast cancer

At the 2008 Annual Meeting of the American Society of Clinical Oncology (ASCO), data were presented from a phase II investigator-sponsored trial paclitaxel poliglumex (Opaxio, CT-2103) in combination with capecitabine in first-line treatment of patients with metastatic breast cancer (MBC).

3 Jun 2008

Cetuximab and chemotherapy combination proves safe, effective for head and neck cancer patients

Patients treated for locally advanced head and neck cancer may respond better to treatment with the addition of cetuximab to chemotherapy, according to a University of Pittsburgh Cancer Institute (UPCI) phase II study. The results will be presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago as an oral presentation.

2 Jun 2008

Study looks at the role of metformin as possible anti-tumor agent

Metformin, the common first-line drug for type 2 diabetes, may be effective in increasing pathologic complete response rates in diabetic women with early stage breast cancer who took the drug during chemotherapy prior to having surgery, paving the way for further research of the drug as a potential cancer therapy, according to researchers at The University of Texas M. D. Anderson Cancer Center.

2 Jun 2008

Celldex Therapeutics vaccine may double survival in patients with deadly brain tumors

A vaccine aimed at inducing immunity to the most common and deadly type of brain tumor may stave off recurrence and more than double survival in patients, according to a new study led by researchers in Duke's Preston Robert Tisch Brain Tumor Center.

2 Jun 2008

Medarex announces preliminary data for investigational anti-PD-1 antibody

Medarex, Inc. has announced preliminary data from an ongoing Phase 1 study of MDX-1106 (ONO-4538: development code of Ono Pharmaceutical Co., Ltd.), a fully human anti-PD-1 antibody.

2 Jun 2008

Genta announces initial trial results for novel drug for bone disease

Genta Incorporated has announced the release of final results from the Company's Phase 1 clinical trial of G4544, a proprietary small molecule that is intended as a treatment for diseases associated with accelerated bone loss. Results showed that the drug was very well-tolerated, and that blood levels were achieved in a range that is known to be clinically bioactive. The data were featured in a poster session at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago on Saturday, May 31, 2008.

2 Jun 2008

Combination biotherapies safe, promising for melanoma patients

The combination of two different biotherapies may be beneficial for patients with inoperable melanoma, according to a University of Pittsburgh Cancer Institute (UPCI) study presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

1 Jun 2008

New studies provide insight into oral cancer, chronic pediatric ear infections, and hearing health

Three new studies published in the June 2008 edition of Otolaryngology - Head and Neck Surgery focus on what role gender plays in the prognosis of oral tongue cancer, chronic ear infections in children, and the success rates of hearing aid implants in the elderly.

1 Jun 2008

Lack of dental care may have life-threatening implications

New research from the University of Bristol shows that admissions for the surgical treatment of dental abscess have doubled in the last ten years despite the fact that these serious infections are preventable with regular dental care.

29 May 2008

Global drug research programme comes to Diamond in Oxfordshire

Diamond has announced that USA-based global biotechnology company Vertex Pharmaceuticals Incorporated is the first industrial user at the UK's world class new research facility, Diamond Light Source

27 May 2008

Avoiding spleen removal for Cooley's anemia sufferers

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans. The World Health Organization estimates that between 50,000-100,000 children are born with the disease each year.

27 May 2008

Oral News and Research

Misoprostol off-label use may have led to deaths

Pomegranate extract may provide humans with relief of chronic inflammatory conditions

Fluoride toothpaste too pricey for world's poorest people

Simple steps can help reduce your risk of contracting potentially deadly superbug

High prevalence of periodontal disease in rheumatoid arthritis found

Having heart surgery? Watch your blood sugar

Specialist nurses can play a key role in supporting patients having radiotherapy, but more investment is needed

FDA grants pediatric exclusivity for UCB's Keppra

Boehringer Ingelheim, Gilead to freeze AIDS drug price

Paclitaxel Poliglumex/Capecitabine regimen well tolerated and active in metastatic breast cancer

Cetuximab and chemotherapy combination proves safe, effective for head and neck cancer patients

Study looks at the role of metformin as possible anti-tumor agent

Celldex Therapeutics vaccine may double survival in patients with deadly brain tumors

Medarex announces preliminary data for investigational anti-PD-1 antibody

Genta announces initial trial results for novel drug for bone disease

Combination biotherapies safe, promising for melanoma patients

New studies provide insight into oral cancer, chronic pediatric ear infections, and hearing health

Lack of dental care may have life-threatening implications

Global drug research programme comes to Diamond in Oxfordshire

Avoiding spleen removal for Cooley's anemia sufferers

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