Protein C News and Research

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Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems.

18 Jun 2021

New hydrogel prevents the formation of adhesions after cardiac surgery

A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers.

18 Jun 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

A new study, released as a preprint on bioRxiv* server, shows that a combination of the biological interferon-α and the small molecule nafamostat are effective against SARS-CoV-2 infection in vitro, as well as in vivo.

18 Jun 2021

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Underlining the key role of genomic surveillance in keeping tabs on the spread of SARS-CoV-2, a new medRxiv* preprint shows how a new variant called B.1.1.318 rose to dominance in the small island country of Mauritius, in the Indian Ocean.

18 Jun 2021

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

A new study, released as a preprint on the bioRxiv* server, reveals the high neutralizing efficacy of hyperimmune horse serum against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could prove, if validated, to be a more affordable yet potent therapeutic in reducing the morbidity and mortality caused by this virus.

18 Jun 2021

First insights into human prion disease could help tackle neurodegenerative diseases

Surface features of human prions have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases.

18 Jun 2021

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

A new study shows that depleting mouse blood of the protein ADORA2B led to faster declines in memory, and increased brain inflammation.

18 Jun 2021

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

In early January 2021, travelers returning to Tokyo, Japan, from Amazonas, Brazil, were screened for COVID-19 at the airport. A few days later, the National Institute of Infectious Disease of Japan announced that the travelers had returned with a new variant of the SARS-CoV-2 virus.

18 Jun 2021

Protein found in mice’s immune system could protect babies from necrotizing enterocolitis

The intestinal disease necrotizing enterocolitis is a leading cause of death among premature infants born in the U.S. and across the globe.

18 Jun 2021

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Despite tremendous efforts by the global scientific community to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by developing more efficient testing protocols, therapies, and vaccines at a rapid pace, relatively little is known about the dynamics of SARS-CoV-2 replication within cells.

18 Jun 2021

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.

18 Jun 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

Which vitamins and minerals help with COVID?

A study published in the journal Inflammopharmacology reviewed recent data related to the role of vitamins and minerals in treating COVID-19 patients. The primary goal of the review is to highlight the possible therapeutic role of vitamins A, B, C, D, E and K, and micronutrients as immunity boosters in COVID-19 patients.

18 Jun 2021

New methods may lead to optimal treatment for lung cancer

Today as they did 100 years ago, doctors diagnose cancer by taking tissue samples from patients, which they usually fix in formalin for microscopic examination.

18 Jun 2021

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.

18 Jun 2021

Protein C News and Research

Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

New hydrogel prevents the formation of adhesions after cardiac surgery

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

First insights into human prion disease could help tackle neurodegenerative diseases

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

Protein found in mice’s immune system could protect babies from necrotizing enterocolitis

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Which vitamins and minerals help with COVID?

New methods may lead to optimal treatment for lung cancer

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

New details on transport protein could help develop drugs for neurological diseases

Researchers create the most comprehensive atlas of human transcriptome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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