Coronavirus News and Research

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New project aims to develop software tool to protect patient data in COVID-19 research

The COVID-19 pandemic has created an urgent need for sharing patient data to help scientists learn more about the virus and how to stop it from spreading.

8 Jun 2020

Innovative effort solves health system's shortage of nasopharyngeal swabs

An innovative effort launched in April and led by a fellow in the UCLA Biodesign program has yielded positive results, solving the health system's shortage of nasopharyngeal swabs - a key element in COVID-19 testing - at a time when Southern California is seeing a rise in new cases and new deaths per day.

8 Jun 2020

56 percent of pregnant women in UK hospitals with COVID-19 are BAME

According to a new national surveillance study released this week, over half of the pregnant women admitted to a hospital in the United Kingdom with COVID-19 are either black or belong to other ethnic minority groups.

8 Jun 2020

Health disparities negatively impact various groups of people

Certain illnesses and diseases have the ability to affect various groups of people in detrimental ways.

8 Jun 2020

Mount Sinai receives award from Microsoft AI for Health to support COVID Informatics Center

The Mount Sinai Health System has received an award from Microsoft AI for Health to support the work of a new data science center dedicated to COVID-19 research.

8 Jun 2020

Synthetic monoclonal antibodies effectively neutralize SARS-CoV-2 in laboratory conditions

In a new study available on the preprint server bioRxiv*, a multinational research group demonstrated how monoclonal antibodies strongly inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro at even sub-nanomolar concentrations. This makes them a prime candidate for the treatment of coronavirus disease (COVID-19).

8 Jun 2020

Improving detection of SARS-CoV-2 infection among severely ill children

Researchers in the UK have conducted a study showing that children with a severe inflammatory syndrome had high levels of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), despite having tested negative for the virus by polymerase chain reaction (PCR).

8 Jun 2020

Kidney complications more prevalent among hospitalized COVID-19 patients at NYC

Hospitalized COVID-19 patients at a New York City medical facility had higher rates of kidney complications than other COVID-19 patient groups in different areas of the U.S. and other countries, according to a new study from researchers at Columbia University Irving Medical Center and NewYork-Presbyterian.

8 Jun 2020

Irradiation with UV light kills SARS-CoV-2

Researchers in Italy have found that it is possible to completely inactivate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using short-wavelength UV (UV-C) irradiation.

8 Jun 2020

Baltimore’s ‘squeegee boys’: ‘If we don’t go out, we don’t eat’

On the corner of South President and East Pratt streets in Baltimore a little over a month ago, a young man in a black hoodie stood out on an otherwise empty intersection.

8 Jun 2020

Rapid changes to health system spurred by COVID might be here to stay

The U.S. health care system is famously resistant to government-imposed change. It took decades to create Medicare and Medicaid, mostly due to opposition from the medical-industrial complex. Then it was nearly another half-century before the passage of the Affordable Care Act.

8 Jun 2020

Study reports reduced intake of fruit and vegetables among children since lockdown

In a study conducted by Northumbria University's Healthy Living Lab around half of the children who received free school meal vouchers are reporting a significant drop in their intake of fruit and vegetables since schools closed in March.

8 Jun 2020

Monocytes could be critical in dysregulated immunity in COVID-19

A new study by Spanish researchers as part of the GEN-COVID Project, and published on the preprint server medRxiv* in June 2020, suggests that monocytes are primarily involved in triggering the hyperinflammatory immune response that may underlie severe COVID-19 infection.

8 Jun 2020

The receptor binding domain of the SARS-CoV-2

With the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across most of the world, scientists are working strenuously to find effective therapies or vaccines. Most strategies being worked on at present are targeting viral entry into the host cells, mainly through the interaction of the SARS-CoV-2 S protein with the angiotensin-converting enzyme 2 (ACE2) receptor.

8 Jun 2020

Inhibition of coronavirus spike protein binding to ACE2

A novel coronavirus, CoV-19, and a later phenotype CoV-2 were identified as the primary cause for severe acute respiratory syndrome (SARS CoV-2). The spike (S) protein of CoV-2 is one target for the development of a vaccine to prevent the viral entry into human cells. The inhibition of the direct interaction between ACE2 and the S-protein could provides a suitable strategy to prevent the membrane fusion of CoV-2 and the viral entry into human cells. Using MD simulations, we investigate the assembly process of a Coronavirus Spike protein fragment, the hexapeptide YKYRYL on the ACE2 receptor and its inhibitzory effect on the aggregation and activation of the CoV-2 spike receptor protein at the same receptor protein.

8 Jun 2020

SARS-CoV-2 genome variants in India

A new study published online on the preprint server bioRxiv in June 2020 surveys the genetic diversity of SARS-CoV-2 strains in India.

7 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020