Neuroscience News and Research

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Otsuka opens Canadian operations

Otsuka Canada Pharmaceutical Inc. has opened its first Canadian office, in the Montreal suburb of Saint-Laurent. This marks a major milestone in the continued growth of Otsuka in North America.

4 Oct 2010

IRSF awards $1.5M in research grants for Rett syndrome treatment

The International Rett Syndrome Foundation (IRSF) announced today that it will award an additional $1.5M in research grants, bringing the 2010 total to $2.15 million for innovative basic and translational research that moves treatments for Rett syndrome a step closer to the clinic.

4 Oct 2010

Scientists discover c-Abl protein role in Parkinson's disease progression

Johns Hopkins scientists have discovered that the over-activation of a single protein may shut down the brain-protecting effects of a molecule and facilitate the most common form of Parkinson's disease.

4 Oct 2010

Cell aging is associated with reduced histone level

Like cats, human cells have a finite number of lives-once they divide a certain number of times they change shape, slow their pace, and eventually stop dividing, a phenomenon called cellular senescence.

4 Oct 2010

LSUHSC-S receives $3.9M NIDA grant to develop EMB-001 drug for cocaine dependence

Embera NeuroTherapeutics, Inc., a specialty pharmaceutical company developing novel treatments for addiction and obesity, announced today that the Louisiana State University Health Sciences Center (LSUHSC-S) has received a $3.9 million dollar grant from the National Institute on Drug Abuse (NIDA). The grant will support the next stages of development for Embera's drug candidate EMB-001 to treat cocaine dependence, as well as advance EMB-001 into clinical testing.

1 Oct 2010

Cortex regains global rights to AMPAKINE compounds for treatment of schizophrenia and depression

Cortex Pharmaceuticals, Inc. announced that it has regained worldwide rights to develop and commercialize its AMPAKINE® compounds for the treatment of schizophrenia and depression.

1 Oct 2010

CSHL professor receives NIH grant to study mechanism behind autism and schizophrenia

Anthony Zador, Ph.D., Professor of Biology and Program Chair in Neuroscience at Cold Spring Harbor Laboratory (CSHL), has been awarded a $2.17 million, 5-year grant by the National Institutes of Health (NIH)'s Transformative Research Projects Program (T-R01).

1 Oct 2010

Swedish Medical Center researcher receives NIH grants to study pregnancy complications

Michelle A. Williams, Sc.D., co-director and principal investigator at the Center for Perinatal Studies at Swedish Medical Center in Seattle and Professor of Epidemiology and Global Health at the University of Washington, has received two grants totaling $5.6 million for research into complications affecting pregnancy.

1 Oct 2010

Study indicates neurotransmitters are abnormal in people with psychotic illness

There is growing evidence that two neurotransmitters - dopamine and glutamate - are abnormal in people with psychotic illness, including schizophrenia. Among many other things, these chemicals play a role in cognitive functions, such as memory, learning, and problem-solving.

1 Oct 2010

New approach to prevent psychotic symptoms

New research has linked psychosis with an abnormal relationship between two signalling chemicals in the brain. The findings, published in tomorrow's edition of the journal Biological Psychiatry, suggest a new approach to preventing psychotic symptoms, which could lead to better drugs for schizophrenia.

30 Sep 2010

Researchers explain why obesity is resistant to treatment

New research provides evidence of the vicious cycle created when an obese individual overeats to compensate for reduced pleasure from food.Obese individuals have fewer pleasure receptors and overeat to compensate, according to a study by University of Texas at Austin senior research fellow and Oregon Research Institute senior scientist Eric Stice and his colleagues published this week in The Journal of Neuroscience.

30 Sep 2010

Research shows dexamethasone treatment effective for bacterial meningitis

New research shows that an intravenous (IV) treatment may cut a person's risk of dying from bacterial meningitis. The research is published in the September 29, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology. The treatment is called dexamethasone.

30 Sep 2010

Medivation and Astellas commence MDV3100 second Phase 3 clinical trial in advanced prostate cancer

Medivation, Inc. and Astellas Pharma Inc. today announced treatment of the first patient in a second Phase 3 clinical trial of the investigational drug MDV3100, which expands the Phase 3 development of the novel, triple-acting oral androgen receptor antagonist into an earlier-stage patient population. Known as PREVAIL, the trial will evaluate MDV3100 in men with advanced prostate cancer who have not yet received chemotherapy. Initiation of the PREVAIL trial triggers a milestone payment to Medivation under its collaboration agreement with Astellas.

29 Sep 2010

Morphotek announces first therapeutic monoclonal antibody for clinical development

Morphotek, Inc., a subsidiary of Eisai Inc., today announced that a monoclonal antibody has been selected for advancement to clinical development under the terms of its March 2009 collaboration agreement with Human Genome Sciences, Inc.

29 Sep 2010

Brain cells outside damaged area in stroke patients take on new roles

The world's largest study using neuroimaging of stroke patients struggling to regain ability to communicate finds that brain cells outside the damaged area can take on new roles.

29 Sep 2010

Scientists discover way of shrinking tumours in cancers

Australian and American scientists have found a way of shrinking tumours in certain cancers - a finding that provides hope for new treatments.

29 Sep 2010

Magnetic pulses disrupt neurons that govern motor skills and make a right-handed person to use the left hand

Each time we perform a simple task, like pushing an elevator button or reaching for a cup of coffee, the brain races to decide whether the left or right hand will do the job. But the left hand is more likely to win if a certain region of the brain receives magnetic stimulation, according to new research from the University of California, Berkeley.

29 Sep 2010

Scientists identify genetic contribution to sense of smell

Scientists at the Monell Center have used a well-known example of individual differences to identify a genetic contribution to the sense of smell. Most people detect a distinct sulfurous odor in their urine shortly after eating asparagus. However, there are some who seemingly do not notice the unpleasant odor.

29 Sep 2010

Research: SorCS1 gene is linked to Alzheimer's disease, Type 2 diabetes

A research team led by Mount Sinai School of Medicine has identified the mechanism behind a single gene linked to the causes of both Alzheimer's disease and Type 2 diabetes.

29 Sep 2010

Early weaning and separation from mothers promotes long-lasting hyperactivity and anxiety in children

In mice, early weaning and separation from their mothers promotes long-lasting hyperactivity and anxiety. Researchers writing in the open access journal BMC Neuroscience describe the development of this new behavioral model, which they hope to use to investigate the long-term effects of early childhood neglect in people.

29 Sep 2010

Neuroscience News and Research

Otsuka opens Canadian operations

IRSF awards $1.5M in research grants for Rett syndrome treatment

Scientists discover c-Abl protein role in Parkinson's disease progression

Cell aging is associated with reduced histone level

LSUHSC-S receives $3.9M NIDA grant to develop EMB-001 drug for cocaine dependence

Cortex regains global rights to AMPAKINE compounds for treatment of schizophrenia and depression

CSHL professor receives NIH grant to study mechanism behind autism and schizophrenia

Swedish Medical Center researcher receives NIH grants to study pregnancy complications

Study indicates neurotransmitters are abnormal in people with psychotic illness

New approach to prevent psychotic symptoms

Researchers explain why obesity is resistant to treatment

Research shows dexamethasone treatment effective for bacterial meningitis

Medivation and Astellas commence MDV3100 second Phase 3 clinical trial in advanced prostate cancer

Morphotek announces first therapeutic monoclonal antibody for clinical development

Brain cells outside damaged area in stroke patients take on new roles

Scientists discover way of shrinking tumours in cancers

Magnetic pulses disrupt neurons that govern motor skills and make a right-handed person to use the left hand

Scientists identify genetic contribution to sense of smell

Research: SorCS1 gene is linked to Alzheimer's disease, Type 2 diabetes

Early weaning and separation from mothers promotes long-lasting hyperactivity and anxiety in children

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