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Nitrates in vegetables protect against gastric ulcers

Vegetables that are rich in nitrates protect the stomach from damage. This takes place through conversion of nitrates into nitrites by the bacteria in the oral cavity and subsequent transformation into biologically active nitric oxide in the stomach. The Swedish researcher Joel Petersson has described the process, which also means that antibacterial mouthwashes can be harmful for the stomach.

7 May 2008

Impact of round-the-clock, rapid oral fluid HIV testing of women in labor

Can HIV transmission in pregnancy in low income settings be prevented with round the clock rapid testing in labor?

6 May 2008

New saliva-based HIV test gives results in 20 minutes!

The usual waiting period for the results of a HIV test can seem like an eternity, especially in emergency situations where results are needed immediately. Also it requires a blood sample, which is invasive and often painful. Recognizing the urgent need for a faster and less invasive diagnostic method, Dr. Nitika Pant Pai, from Marina Klein's research team at the MUHC has just finished testing a new saliva-based test that gives results in approximately 20 minutes! She describes her findings in an article that will appear in the May 6th, 2008 issue of PLoS Medicine.

6 May 2008

New York lawmakers, HIV/AIDS advocates working to address HIV/AIDS funds for counties

New York state lawmakers and HIV/AIDS advocates are working to address federal HIV/AIDS funding for Nassau and Suffolk counties following a recent ruling that HHS should restore more than $1 million in Ryan White Program funding, the New York Times reports (Saslow, New York Times, 5/4).

5 May 2008

Alendronate may improve successful implantation of maxillary bone

A new study has established that estrogen deficiency negatively affects implant osseointegration in rats' maxillary bone.

1 May 2008

AstraZeneca submits sNDA for SYMBICORT in chronic obstructive pulmonary disease

AstraZeneca today announced that it submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for approval of a new indication for SYMBICORT (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol for the treatment of patients with Chronic Obstructive Pulmonary Disease (COPD). SYMBICORT is currently approved for the long-term maintenance treatment of asthma in patients 12 years and older.

30 Apr 2008

Progesterone could prevent brain damage after head injury

A common component of the contraceptive pill (progesterone) could improve the neurologic outcome for patients with severe head injuries, according to a study published in BioMed Central's open access journal Critical Care.

30 Apr 2008

Study explains why steroid therapy for sinusitis and asthma loses its punch over time

Scientists at Johns Hopkins have outlined a new path for potential therapies to combat inflammation associated with sinusitis and asthma based on a new understanding of the body's earliest immune response in the nose and sinus cavities.

29 Apr 2008

Cell-based therapy shows promise in patients with Parkinson's disease

Rush University Medical Center neurosurgeon Dr. Roy A. E. Bakay and colleagues from Emory University, Atlanta found the therapy Spheramine was well-tolerated and patients experienced improvement in Parkinsonian symptoms (tremor, rigidity, slowness of movements, and impaired balance and coordination.)

28 Apr 2008

Thiazolidinediones may slow bone formation and speed bone loss

A widely used class of diabetes medications appears to be associated with an increased risk for fractures, according to a report in the April 28 issue of Archives of Internal Medicine.

28 Apr 2008

Combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer

A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival.

26 Apr 2008

Amneal Pharmaceuticals to acquire assets of Interpharm Holdings

Amneal Pharmaceuticals, LLC has announced the execution of an Asset Purchase Agreement for Amneal's wholly-owned subsidiary, Amneal Pharmaceuticals of New York, LLC, to acquire the assets, facilities and business of Interpharm. The acquisition includes Interpharm's facilities on Long Island, New York as well as the intellectual property including ANDA's, technology and processes.

24 Apr 2008

Tredaptive and Janumet recommended for approval in European Union

Food and Drug Administration (FDA) is currently reviewing the combination of extended release (ER) niacin and laropiprant under the trademark Cordaptive (ER niacin/laropiprant). The CHMP recommendation does not apply to regulatory decisions by the FDA and no inferences should be made about pending FDA regulatory actions based on the recommendation of the CHMP.

24 Apr 2008

Protein HtpG signals healthier teeth and gums

Antibodies present in people with good oral health could become the first tool for dental professionals to assess a patient's probable response to periodontal disease treatments, say researchers at the University of Michigan.

23 Apr 2008

MacroChem acquires Virium Pharmaceuticals

MacroChem Corporation announced today that on April 18, 2008 it acquired Virium Pharmaceuticals Inc., a non-public, development stage company developing and commercializing novel therapeutics, with a portfolio of clinical stage product candidates focused in oncology, including its next generation nucleoside analogue licensed from the Southern Research Institute.

23 Apr 2008

Hirsutism in premenopausal women - new treatment guidelines

The Endocrine Society has released new clinical practice guidelines for the treatment of hirsutism in premenopausal women. The guidelines appear in the April issue of the Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of The Endocrine Society.

22 Apr 2008

Taro Pharmaceutical receives final FDA approval for Cetirizine Hydrochloride oral solution

Taro Pharmaceutical Industries Ltd. reported today that it has received final approval from the U.S. Food and Drug Administration ("FDA") for its Abbreviated New Drug Application ("ANDA") for cetirizine hydrochloride oral solution, 1 mg / 1 mL ("Cetirizine Oral Solution").

22 Apr 2008

BioAlliance Pharma announces preliminary results from U.S. phase III trial for Loramyc

BioAlliance Pharma SA today announced the preliminary positive results for its US pivotal Phase III clinical trial with Loramyc (miconazole Lauriad), Mucoadhesive Buccal Tablets (MBT) developed for the treatment of OroPharyngeal Candidiasis in immunocompromised population. This trial was conducted to support an NDA filing to market the product in the US.

21 Apr 2008

Raptor Pharmaceuticals initiates phase IIa clinical study for Convivia

Raptor Pharmaceuticals Corp. has announced that its clinical development subsidiary, Bennu Pharmaceuticals Inc. , has initiated the Company's first clinical-stage program after dosing the first cohort in a Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

21 Apr 2008

Dental sealants still offer best protection against tooth decay says the BC Dental Association

Dental sealants remain one of the best methods for protection against tooth decay in children, says the BC Dental Association. The Association supports Health Canada's announcement that bisphenol-A (BPA) in dental resin materials poses no significant health threat.

20 Apr 2008