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Rice University researcher to see how delays in gene transcription affect cellular processes

A Rice University researcher and his colleagues have received a National Institutes of Health grant to see how delays in gene transcription - life's most basic messaging system - affect cellular processes.

16 Aug 2012

Two studies examine psychological status of Fukushima workers after nuclear plant disaster

The results of two studies in the August 15 issue of JAMA report on the psychological status of workers at the Fukushima nuclear power plants in Japan several months after the earthquake and tsunami in March 2011, and the amount of internal radiation exposure among residents of a city north of the power plant that experienced a meltdown.

16 Aug 2012

Pouch surgery has long-term costs for young patients

Restorative proctocolectomy with ileal pouch-anal anastomosis is associated with high complication rates and poor body image in patients who undergo the procedure at a young age, research shows, with women at additional risk for sexual dysfunction.

15 Aug 2012

Mechanism for chemotherapy resistance identified

Researchers have identified that chemotherapy induces subsequent treatment resistance through damaging healthy tissue, which in turn secretes novel factors that sustain the growth of residual tumor cells.

15 Aug 2012

Cortisol levels increased in youth at high risk for psychosis

Untreated young people at clinical high risk for psychosis have increased salivary cortisol levels compared with treated high-risk patients and mentally healthy individuals, study results show.

15 Aug 2012

Couple therapy decreases PTSD symptoms and improves relationship

A North American study led by a researcher at Ryerson University has discovered that treating a person with posttraumatic stress disorder (PTSD) and their partner using a specific couple therapy greatly decreases the severity of their symptoms -- and improves their relationship.

15 Aug 2012

TG2 plays a key role in serotonin deficiency associated with depression

Connecting the dots between two molecules whose levels are decreased in depression and increased by current antidepressants could yield new therapies, researchers say.

15 Aug 2012

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

University of Utah Department of Medicine researchers have received $16 million from the National Institutes of Health (NIH) to set up a translational research center to study the cellular and molecular causes of blood clots, a serious threat to millions of people who have diabetes, are obese or have other metabolic disorders.

15 Aug 2012

Mindfulness meditation prevents feelings of loneliness

Many elderly people spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.

15 Aug 2012

Two papers may help identify gene variants that contribute to OCD or Tourette syndrome

Two papers that will appear in the journal Molecular Psychiatry, both receiving advance online release, may help identify gene variants that contribute to the risks of developing obsessive-compulsive disorder (OCD) or Tourette syndrome (TS). Both multi-institutional studies were led by Massachusetts General Hospital (MGH) investigators, and both are the first genome-wide association studies (GWAS) in the largest groups of individuals affected by the conditions.

15 Aug 2012

Catechins may help reduce neurological complications linked to HIV

Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications.

15 Aug 2012

TAIN project aims to optimise treatment for babies with adrenal insufficiency

Groundbreaking research into rare neonatal diseases, conducted by the University of Sheffield, is set to improve the treatment of babies who lack the stress hormone cortisol.

15 Aug 2012

Fruit juice may reduce chocolate's fat content

Scientists have found a way to replace up to 50 per cent of chocolate's fat content with fruit juice.

15 Aug 2012

Depressed cardiac patients at added risk

Coronary artery disease patients may have an increased risk for peripheral arterial disease if they are depressed, study findings show.

14 Aug 2012

Gadd45a protein plays a key role in skeletal muscle atrophy

Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle-even slight or gradual-is about as common to the human condition as breathing.

14 Aug 2012

Smoking is bad for your sperm

In men with varicocele, smoking alters semen quality and sperm function as well as inducing seminal oxidative stress, report researchers.

13 Aug 2012

Medical ethics: an interview with Anita Silvers

Medical ethics assists healthcare professionals to make decisions respectful of persons who happen to be their patients.

13 Aug 2012

Scientists discover why major depression or chronic stress can cause loss of brain mass

Major depression or chronic stress can cause the loss of brain volume, a condition that contributes to both emotional and cognitive impairment. Now a team of researchers led by Yale scientists has discovered one reason why this occurs - a single genetic switch that triggers loss of brain connections in humans and depression in animal models.

13 Aug 2012

Research focuses on evolution of sex and gamete function

The propagation of every animal on the planet is the result of sexual activity between males and females of a given species. But how did things get this way? Why two sexes instead of one? Why are sperm necessary for reproduction and how did they evolve? These as-yet-unresolved issues fascinate Timothy Karr, a developmental geneticist and evolutionary biologist at Arizona State University's Biodesign Institute.

13 Aug 2012

Scientists discover how pten gene causes brain changes that lead to autism-like behavior

Scientists affiliated with the UC Davis MIND Institute have discovered how a defective gene causes brain changes that lead to the atypical social behavior characteristic of autism. The research offers a potential target for drugs to treat the condition.

13 Aug 2012