Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Researchers investigated the mutations reported in the Omicron variant and its likely impact on the use of therapeutic antibodies in COVID-19 treatment as well as on vaccinated individuals.

17 Dec 2021

Investigating SARS-CoV-2 genomics-informed outbreaks using new bioinformatics tools

Researchers have created a tool designed to make as much use of the overwhelming amount of SARS-CoV-2 data as possible.

17 Dec 2021

Prediction of waning COVID-19 vaccine efficacy against Omicron variant

Researchers performed a meta-analysis of the results of four previous studies estimating fold-drop in neutralization titer against Omicron to present a combined estimate of the same.

17 Dec 2021

Analysis of the alteration of neutralizing titers with Omicron pseudovirus

A new study measured antibody levels from blood samples of vaccinated individuals and individuals who recovered from COVID-19 illness.

17 Dec 2021

Comparison of RBD/ACE2 receptor complex in wild type SARS-CoV-2 and Omicron variant

New research details the molecular landscape of Omicron’s RBD and how it differs from the original SARS-CoV-2 strain.

17 Dec 2021

Researchers identify a transporter protein in the brain that plays a vital role in habituation

In habituation, an organism gets so used to a ubiquitous sight, smell, sensation or sound that it virtually disappears. Runa Hamid of the CSIR-Centre for Cellular and Molecular Biology in Hyderabad, India, and colleagues have identified a transporter protein in the brain that plays a vital role in habituation, which they report in a new study publishing December 16th in the journal PLOS Genetics.

17 Dec 2021

Study: Common gene mutation for Parkinson's disease drives mislocalization of iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues

17 Dec 2021

Antibody-like proteins derived from sharks may be used to combat future SARS outbreaks

Small, unique antibody-like proteins known as VNARs - derived from the immune systems of sharks - can prevent the virus that causes COVID-19, its variants, and related coronaviruses from infecting human cells, according to a new study published Dec. 16.

16 Dec 2021

Cedars-Sinai researchers discover growth hormone in the colon that influences aging process

Investigators at Cedars-Sinai have identified growth hormone in the colon that increases as the colon ages—a discovery that can help guide the development of a new anti-aging therapy.

16 Dec 2021

New study demonstrates SARS-CoV-2 Omicron antibody escape

A new study examined the neutralization of virus variants using three sets of antibodies: serum from individuals vaccinated or infected with earlier variants of the virus; concentrated human antibodies from plasma donors; and approved monoclonal antibodies.

16 Dec 2021

Moderna booster vaccination overcomes SARS-CoV-2 Omicron variant antibody escape

A new study reports the results of a study focused on immune evasion characteristics, specifically the ability to escape neutralization by antibodies to the earlier SARS-CoV-2 variants or to the spike antigen used in COVID-19 vaccines.

16 Dec 2021

Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers

Mutations in a histone regulator protein are linked to both a rare neurodevelopmental disorder and to some cancers, according to a study published in the journal Genes and Development.

16 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

A new study found that the Omicron S protein evades antibodies with a 44-fold higher efficiency than the Delta variant's spike, rendering therapeutic antibodies ineffective and likely negatively impacting antibody protection induced by infection or double vaccination.

16 Dec 2021

Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

Treatment for high blood pressure during pregnancy appears safe and reduces maternal risk

Treatment for high blood pressure during pregnancy appears safe for many women and may reduce maternal risk for severe hypertension without increasing fetal and neonatal risks, according to a new American Heart Association scientific statement published today in the Association's journal Hypertension.

16 Dec 2021

Scientists find better treatment options for patients with advanced colorectal cancer

City of Hope, a world-renowned cancer research and treatment organization, today announced study results of a Phase 2 clinical trial showing monotherapy with sotorasib resulted in anti-tumor activity and a favorable benefit-risk profile among heavily pretreated patients with advanced colorectal cancer. The research was published today in Lancet Oncology.

16 Dec 2021

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

A new study highlights the significance of robust T cell responses in preventing severe omicron infections.

16 Dec 2021

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

A new study has used this assay to evaluate sera, obtained from 239 individuals vaccinated via any of the above-stated vaccines against SARS-CoV-2’s original strain, the Delta, and Omicron SARS-CoV-2 pseudoviruses.

16 Dec 2021

Researchers develop novel method to supplement cow milk with vegetable protein

Scientists from the Department of Food Science and Technology at The Ohio State University (Columbus, Ohio, USA) have developed a novel method of supplementing cow milk with vegetable protein using readily available current dairy processing equipment.

16 Dec 2021

Protein News and Research

Further Reading

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Investigating SARS-CoV-2 genomics-informed outbreaks using new bioinformatics tools

Prediction of waning COVID-19 vaccine efficacy against Omicron variant

Analysis of the alteration of neutralizing titers with Omicron pseudovirus

Comparison of RBD/ACE2 receptor complex in wild type SARS-CoV-2 and Omicron variant

Researchers identify a transporter protein in the brain that plays a vital role in habituation

Study: Common gene mutation for Parkinson's disease drives mislocalization of iron in the brain

Antibody-like proteins derived from sharks may be used to combat future SARS outbreaks

Cedars-Sinai researchers discover growth hormone in the colon that influences aging process

New study demonstrates SARS-CoV-2 Omicron antibody escape

Moderna booster vaccination overcomes SARS-CoV-2 Omicron variant antibody escape

Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

Experimental and computational synergy considered a promising approach in COVID-19 patients

Treatment for high blood pressure during pregnancy appears safe and reduces maternal risk

Scientists find better treatment options for patients with advanced colorectal cancer

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

Researchers develop novel method to supplement cow milk with vegetable protein

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