Therapy News and Research

RSS

Small molecules block SARS-CoV-2 spike-ACE2 attachment

The search includes immunological agents, enzyme inhibitors, and soluble competitive inhibitors. Now, a new study published on the preprint server bioRxiv in October 2020 provides preliminary evidence that small molecules can inhibit viral entry by inhibiting spike-ACE2 attachment.

26 Oct 2020

New inhibitor of SARS-CoV-2 RNA translation

As the search for effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors continues, a recent study by Yale University School of Medicine researchers published on the preprint server bioRxiv in October 2020 reports the inhibitory effect of the drug merofloxacin on frameshifting during SARS-CoV-2 replication.

26 Oct 2020

Mathematical modeling study offers new insights into optimal timing of antiviral therapies against COVID-19

A new mathematical modeling study by Ashish Goyal and colleagues, informed by data collected from 25 patients hospitalized with COVID-19 in 4 different countries, offers some important new insights into the optimal timing of 4 different antiviral therapies to combat the disease.

23 Oct 2020

Age can affect response to adjuvant treatment among patients with resected melanoma

Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not

23 Oct 2020

Researchers find a new therapeutic approach to combat leukemia

Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, have found a new way to make these cells vulnerable by specifically dislodging these cells from their niches.

23 Oct 2020

High-impact clinical trial results could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.

23 Oct 2020

Investigational drug offers benefits for patients with chronic kidney disease and type 2 diabetes

The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology's Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes.

23 Oct 2020

Review: Twitter can be a useful resource not only for breast cancer patients but also for doctors

A UCLA-led review of nine years of social media posts with the hashtag BCSM suggests that Twitter can be a useful resource not only for patients, but also for physicians and researchers.

23 Oct 2020

New method can detect high levels of COVID-19 antibodies

A more efficient and much faster method to assess high levels of neutralizing antibodies to COVID-19 could point the way to better understanding and treatment of the disease, according to new published findings by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) and the University of Michigan (U-M).

23 Oct 2020

Researchers create AI system that matches tumors to best drug combinations

Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

23 Oct 2020

New therapeutic approach for treating patients with compromised immune systems

A young woman who had been hospitalized for three months straight due to debilitating, recurrent infections with no apparent underlying cause was finally able to go home thanks to a Massachusetts General Hospital (MGH) team who put their heads together, discovered a root of the problem, and developed a novel treatment strategy just for her.

23 Oct 2020

Vitamin C and COVID-19: A Review

In a recent review published in Preprints*, Patrick Holford et al. address vitamin C's role as adjunctive therapy for respiratory infection, sepsis, and COVID-19.

23 Oct 2020

Seropositivity to SARS-CoV-2 among asymptomatic blood donors in New York

New York was the hardest-hit U.S. state during the peak of the outbreak in the country. Now, a team of researchers from the New York Blood Center and Serimmune, an immune intelligence company, aimed to determine the prevalence of seropositive people for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, among healthy blood donors.

23 Oct 2020

Researchers show a simple way to protect transplanted islets from rejection

Type 1 diabetes, or T1D, results from the autoimmune destruction of the insulin-producing cells of the pancreas. People with T1D require exogenous insulin and suffer swings in the levels of glucose in the blood that impact life expectancy and increase risks of cardiovascular disease, neuropathies and kidney failure.

22 Oct 2020

Hurricanes may impact use of at-home obstructive sleep apnea treatment

Hurricanes impact obstructive sleep apnea patients' ability to use positive airway pressure (PAP) therapy not only during, but also before and after the storm, according to a scientific investigation by University of Miami Miller School of Medicine researchers published in the Journal of Clinical Sleep Medicine.

22 Oct 2020

UMass Lowell research projects receive nearly $12 million in federal funding

UMass Lowell research projects, ranging from developing new protective gear and sensors to ensure food and water are safe to advanced wireless communications, were recently awarded nearly $12 million in federal funding through the Fiscal Year 20 Defense Appropriations bill.

22 Oct 2020

Virginia Tech doctoral candidate wins NIH award to fuse immunology and neuroscience research

Gabriela Carrillo didn't always aspire to be a neuroscientist. It wasn't until she was providing in-home behavioral analysis therapy for children with autism that she was drawn to the lab.

22 Oct 2020

Study: Antiretroviral therapy fails to restore age-appropriate epigenetic patterns

Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to aging-related illnesses.

22 Oct 2020

New method for producing FTVI enzyme can help improve cord blood transplants

A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

22 Oct 2020

Santen joins forces with ophthalmologists in the fight against antibiotic resistance

Santen is delighted to announce the launch of the Re-SOLVE Antibiotic Resistance, which aims to lead the way in the fight against antibiotic resistance.

22 Oct 2020