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Identifying new mechanism for aspirin in cancer prevention

Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it necessary to better understand the mechanisms by which aspirin acts at low doses before recommending it more generally as a preventative, says Cornelia Ulrich, PhD, Senior Director of Population Sciences at Huntsman Cancer Institute in Salt Lake City.

19 Nov 2015

Role of genetic predisposition in pediatric cancer patients

The most detailed analysis yet of the role germline mutations in genes associated with cancer predisposition play in the development of childhood cancer suggests that comprehensive genomic screening may be warranted on all pediatric cancer patients, not just those with a family history of cancer.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

Georgia State University researchers develop a method to better trace and treat cancer

A method to better trace changes in cancers and treatment of the prostate and lung without the limitations associated with radiation has been developed by Georgia State University researchers.

18 Nov 2015

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Med Data Quest, a pioneering medical informatics total solution provider, today celebrates its successful collaboration with the Oncology Business Unit of the CRO giant WuXi AppTec, delivering the world's first mobile App OncoWuXi that was launched in October for customers to access WuXi oncology tumor models and capabilities more quickly and easily for cancer drug discovery and translational research.

18 Nov 2015

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer.

18 Nov 2015

Novel immunotherapeutic approach could improve outcomes for patients with advanced bladder cancer

Noguchi explained that immunotherapy has emerged recently as a viable and attractive strategy for the treatment of advanced cancer.

18 Nov 2015

UCLA researchers find new way to reduce ascites with minimal side effects

Women who have ovarian cancer often develop a condition called ascites, which is a buildup of fluids in the abdomen. The most common treatment for ascites is puncturing the abdomen and manually draining the fluid, which is painful and risky and must be repeated every few weeks.

18 Nov 2015

MicroRNA reduces tumor growth, increases cell death in castration-resistant prostate cancer

Researchers at the UC Davis Comprehensive Cancer Center have shown that the microRNA, miR-124, reduced tumor growth and increased cell death in castration-resistant prostate cancer.

17 Nov 2015

AstraZeneca announces FDA approval of TAGRISSO (AZD9291) for treatment of lung cancer patients

AstraZeneca today announced that the US Food and Drug Administration has approved TAGRISSO (AZD9291) 80mg once-daily tablets for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA-approved test, who have progressed on or after EGFR tyrosine kinase inhibitor (TKI) therapy.

17 Nov 2015

Study reveals why colorectal cancer still returns in some patients after treatment

Cetuximab, marketed as Erbitux, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.

17 Nov 2015

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

The International Association for the Study of Lung Cancer commends the U.S. Food and Drug Administration's (FDA) decision to grant accelerated approval for osimertinib (Tagrisso), an oral medication for advanced non-small cell lung cancer (NSCLC) patients with a specific epidermal growth factor receptor (EGFR) mutation (T790M) and following progression after previous EGFR inhibitor therapies.

17 Nov 2015

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Researchers at the University of Arizona have invented a device that for the first time allows neurosurgeons, who use microscopes extensively while operating, to see blood flowing inside vessels and more clearly distinguish cancerous from healthy tissue under the microscope.

17 Nov 2015

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

FDA grants accelerated approval for Tagrisso to treat patients with advanced NSCLC

Today, the U.S. Food and Drug Administration granted accelerated approval for an oral medication to treat patients with advanced non-small cell lung cancer (NSCLC). Tagrisso (osimertinib) is now approved for patients whose tumors have a specific epidermal growth factor receptor (EGFR) mutation (T790M) and whose disease has gotten worse after treatment with other EGFR-blocking therapy.

14 Nov 2015

Cornell biomedical engineers develop 'super natural killer cells' to destroy cancer cells in lymph nodes

Cornell biomedical engineers have developed specialized white blood cells - dubbed "super natural killer cells" - that seek out cancer cells in lymph nodes with only one purpose: destroy them.

13 Nov 2015

Presence of connexin proteins suppresses primary tumor growth

How does a protein called connexin put the clamps on cancer? Researchers in the School of Medicine at The University of Texas Health Science Center at San Antonio today reported an explanation.

13 Nov 2015

TGen: PPF drug could help treat patients with deadly brain cancer

In a significant breakthrough, the Translational Genomics Research Institute has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

13 Nov 2015

Drug combination produces long-term responses in patients with mantle cell lymphoma

New research from Moffitt Cancer Center and its collaborators find that the drug combination rituximab plus lenalidomide was effective and produced long-term responses in patients with mantle cell lymphoma.

13 Nov 2015

New antenna-like device makes breast cancer surgery easier for surgeons

Breast cancer surgeons routinely face a dilemma: how to find tumors they cannot feel. Before going into the operating room they must use some method to locate them. Currently, the method they use requires a radiologist to insert a device into the woman's breast.

12 Nov 2015

Tumor News and Research

Identifying new mechanism for aspirin in cancer prevention

Role of genetic predisposition in pediatric cancer patients

International task force aims to develop new approach to cancer prevention and treatment

Georgia State University researchers develop a method to better trace and treat cancer

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Novel immunotherapeutic approach could improve outcomes for patients with advanced bladder cancer

UCLA researchers find new way to reduce ascites with minimal side effects

MicroRNA reduces tumor growth, increases cell death in castration-resistant prostate cancer

AstraZeneca announces FDA approval of TAGRISSO (AZD9291) for treatment of lung cancer patients

Study reveals why colorectal cancer still returns in some patients after treatment

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

FDA grants accelerated approval for Tagrisso to treat patients with advanced NSCLC

Cornell biomedical engineers develop 'super natural killer cells' to destroy cancer cells in lymph nodes

Presence of connexin proteins suppresses primary tumor growth

TGen: PPF drug could help treat patients with deadly brain cancer

Drug combination produces long-term responses in patients with mantle cell lymphoma

New antenna-like device makes breast cancer surgery easier for surgeons

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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