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Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Researchers at the University of São Paulo (USP) in Brazil have identified a new class of molecules capable of stopping the excessive inflammation typical of the severe form of COVID-19 without impairing the immune response to SARS-CoV-2, the virus that causes the disease.

25 Jul 2023

Single target, multiple possibilities: microRNA holds promise for epilepsy treatment

Study investigated the role of micro-ribonucleic acid (miRNA) miR-335-5p as a potential therapeutic target for epilepsy.

25 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

Intensive exercise slows the course of Parkinson's disease, study finds

Neuroscientists from the Faculty of Medicine of the Catholic University, Rome Campus, and the A. Gemelli IRCCS Polyclinic Foundation found that intensive exercise could slow the course of Parkinson's disease and described the biological mechanisms.

14 Jul 2023

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome sequencing technology Stereo-seq and snRNA-seq technology, which provides a molecular and cellular basis for further investigation into neural circuits.

14 Jul 2023

Adiponectin can be a potential therapeutic target for obesity and diabetes

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people, it reverses damage to fatty tissue.

11 Jul 2023

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

A study conducted at the University of São Paulo (USP) in Brazil shows that brilacidin, a new drug tested for treatment of diseases ranging from bacterial skin infections to COVID-19, can kill drug-resistant strains of fungi when combined with two classes of antifungals available on the market.

10 Jul 2023

FKBP5 deficiency linked to atrial fibrillation

Atrial fibrillation (AFib) is the most common type of heart arrhythmia. This serious condition occurs when the heart beats so fast that the upper chambers of the heart quiver.

6 Jul 2023

Vaping nicotine during pregnancy may be no safer for developing fetus than smoking cigarettes

Researchers at the University of Colorado Anschutz Medical Campus have found that vaping nicotine during pregnancy may be no safer for a developing fetus than smoking cigarettes.

5 Jul 2023

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Regular physical exercise, such as resistance training, can prevent Alzheimer's disease, or at least delay the appearance of symptoms, and serves as a simple and affordable therapy for Alzheimer's patients.

3 Jul 2023

Caffeine found to be most effective for treating birth asphyxia

Brain damage caused by oxygen deficiency at birth is one of the main causes of death in newborns worldwide. Using a small animal model, researchers from the University Hospital Bonn (UKB) and DZNE tested treatment with 25 different active agents.

3 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

Experimental antibody treatment shows promise for preventing bone marrow transplant complication

An experimental antibody treatment largely prevented a bone marrow transplant complication called graft versus host disease (GVHD) in the intestines, without causing broad immune suppression, in a preclinical study led by researchers from Penn Medicine and Dana-Farber/Boston Children's Cancer and Blood Disorders Center and published today in Science Translational Medicine.

28 Jun 2023

Animal Model News and Research

Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Single target, multiple possibilities: microRNA holds promise for epilepsy treatment

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

Intensive exercise slows the course of Parkinson's disease, study finds

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

Adiponectin can be a potential therapeutic target for obesity and diabetes

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

FKBP5 deficiency linked to atrial fibrillation

Vaping nicotine during pregnancy may be no safer for developing fetus than smoking cigarettes

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Caffeine found to be most effective for treating birth asphyxia

Spanish researchers develop new immunotherapy combination for liver cancer

Experimental antibody treatment shows promise for preventing bone marrow transplant complication

CBD and THC: promising remedies for aluminum-related neurological damage

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

Oral probiotic bacterial strain found to improve dry eye disease in animal model

Penn research bolsters scientific understanding behind why some people are more prone to allergies

UC researchers discover treatment for a rare cancer-like lung disease in women

Synthetic compound used in perfumes shows potential to stop coagulopathy during a massive hemorrhage

Mutations that lead to intracranial aneurysms discovered

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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