CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Building flexible governance for biological data powering AI systems

In a Policy Forum, Doni Bloomfield and colleagues discuss the need for expanded – yet tailored and flexible – governance for the biological data used to develop powerful artificial intelligence (AI) models.

6 Feb 2026

Contextual errors limit real-world performance of medical AI

Medical artificial intelligence is a hugely appealing concept. In theory, models can analyze vast amounts of information, recognize subtle patterns in data, and are never too tired or busy to provide a response.

3 Feb 2026

Study aims to explore how noise in nurseries affects early language development

Nearly two million children in the UK are affected by early language delays. New research will examine whether noise in nurseries is a hidden factor.

3 Feb 2026

Oxybutynin shows promise in managing hot flashes for prostate cancer patients

A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer.

2 Feb 2026

Family remains central to elder care responsibilities in America

Americans believe that the family as a whole-especially a spouse or partner-is responsible for caring for an older adult.

30 Jan 2026

Innovative light control technique improves miniature endoscopic imaging capabilities

Endoscopic optical coherence tomography is widely used to visualize tissue microstructures in real time, but current probes face clear limitations.

30 Jan 2026

Navigating the multi-dimensional world of modern cancer research

An enduring challenge for the study of human cancer is just how complex it is: how many different ways there are for cancers to originate, progress, and spread in the people who are diagnosed with them.

30 Jan 2026

Understanding caregivers' perceptions when witnessing episodes of terminal lucidity in children

Research assessed caregivers' perceptions when witnessing episodes of terminal lucidity in children. The findings indicate that witnessing these episodes was regarded as a profoundly spiritual experience, capable of influencing personal belief systems.

22 Jan 2026

Study finds late-career physician screening programs often lack fairness

Nearly 1 in 4 U.S. physicians with an active license is over age 65. This has spurred a small minority of hospitals to enact policies to assess these caregivers' cognitive and physical health, with the aim of reducing lapses that harm patients.

21 Jan 2026

Rice’s SynthX Center leads interdisciplinary effort to tackle rare lymphatic disorders

Rice University's SynthX Center, directed by Han Xiao, has received an up to five-year, $18 million award from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program to develop innovative solutions for lymphatic diseases.

20 Jan 2026

New AI learning tool bridges communication gaps between autistic and neurotypical people

People with autism have brains that are wired differently. This can make them especially strong in some areas-such as noticing patterns, remembering details, or thinking logically-while making other things like social cues or changes in routine more challenging.

20 Jan 2026

GOP cuts will cripple Medicaid enrollment, warns CEO of largest public health plan

When the head of the nation's largest publicly operated health plan worries about the looming federal cuts to Medicaid, it's not just her job. It's personal.

15 Jan 2026

AI tool helps clinicians quickly understand complex patient medical histories

An AI-guided platform at Penn Medicine allows clinicians to quickly and easily unearth pertinent information from patients’ electronic health records that otherwise might have been difficult to find.

14 Jan 2026

Making food labels easier to read didn’t stop unhealthy eating

A UK study reveals that food label readability initially reduced sandwich consumption, but effects faded over time, questioning uniform labeling policies.

13 Jan 2026

DNA analysis of colorectal polyps improves diagnosis and treatment

In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.

12 Jan 2026

RNA gene mutations identified as cause of inherited blindness

Researchers from Radboud university medical center and University of Basel have discovered new genetic causes of inherited blindness.

9 Jan 2026

ASTRO rebrands research foundation to accelerate innovation in radiation oncology

The American Society for Radiation Oncology (ASTRO) announced today that it rebranded its research foundation, formerly the Radiation Oncology Institute (ROI), as Speed of Light – The ASTRO Foundation, marking a new chapter in ASTRO's commitment to advancing research and improving patient care in radiation oncology.

6 Jan 2026

Calculator offers accurate scoring of multilingual language ability

More than half of the world's population speaks more than one language-but there is no consistent method for defining "bilingual" or "multilingual." This makes it difficult to accurately assess proficiency across multiple languages and to describe language backgrounds accurately.

5 Jan 2026

Menopause hormone therapy not linked to dementia risk in women

A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.

22 Dec 2025

AI-driven skilling linked to lower burnout and greater worker autonomy

University of Phoenix College of Doctoral Studies announced the publication of "Burnout and Autonomy in the Modern Workforce: The Role of AI-Driven Skilling in Equity and Resilience," a new white paper by Rheanna Reed, D.M., which draws on five years of University of Phoenix Career Optimism Index data, to examine how burnout, autonomy, equity and artificial intelligence (AI) intersect in the U.S. workforce and outlines strategies employers can use to build a more resilient, future-ready workforce.

19 Dec 2025