Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

New study highlights gender differences in diagnosing heart condition

Women may be missing a diagnosis of a potentially deadly heart condition due to guidelines that don't account for natural differences in sex and body size, according to a new study led by UCL (University College London) researchers.

10 Jan 2025

Trametinib shows promise in treating severe hypertrophic cardiomyopathy in children

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published today in JACC: Basic to Translational Science.

8 Jan 2025

NUS researchers enhance chemotherapy with magnetic field pulses

Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects.

6 Jan 2025

HEARTS Act signed into law to protect students from cardiac arrest

President Biden earlier this week signed into law the bipartisan Cardiomyopathy Health Education, Awareness, Research and Training in Schools (HEARTS) Act, which will help ensure students and staff in schools nationwide are prepared to respond to a cardiac emergency.

26 Dec 2024

New study identifies potential target for treating diabetic cardiomyopathy

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders.

12 Dec 2024

American Heart Association launches initiative to improve hypertrophic cardiomyopathy care

An estimated 1 in 500 people in the U.S. are living with hypertrophic cardiomyopathy (HCM) - the most common inherited heart disease - and many are unaware.

4 Dec 2024

Serum protein panel test can help identify cardiomyopathy risk in childhood cancer survivors

Early disease detection is beneficial for securing the best possible outcomes for patients. But finding noninvasive, effective ways to predict disease risk is a tremendous challenge.

3 Dec 2024

Study reveals new genetic explanation for dilated cardiomyopathy

A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single "aberrant" genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College London and the MRC Laboratory of Medical Sciences.

21 Nov 2024

Children's Colorado earns prestigious cardiomyopathy recognition

Children's Hospital Colorado (Children's Colorado) has been named a Cardiomyopathy Center of Care by the Children's Cardiomyopathy Foundation (CCF), a national nonprofit committed to improving health outcomes and quality of life for children with cardiomyopathy.

20 Nov 2024

Benefits of sport and leisure activities outweigh the risks for people with heart disease, cardiologists say

While exercise is generally beneficial for a person's overall health, physical activities may increase the risk of adverse cardiovascular disease events in certain susceptible individuals. However, cardiologists say that the benefits outweigh the risks.

19 Nov 2024

Common heart failure drug reduces risk of chemotherapy-induced heart damage in cancer patients

A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines, according to preliminary late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Tirzepatide improves heart health and function in obese HFpEF patients

In the international SUMMIT trial, adults with heart failure preserved ejection fraction (HFpEF) and obesity taking tirzepatide for up to 3 years had a reduced combined risk of worsening heart failure events and cardiovascular death, and improved health status and physical function in comparison to participants taking placebo, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

AI-powered ECG model predicts heart disease risk with precision

A new AI-enhanced ECG model, AIRE, accurately predicts mortality and heart disease risk, providing clinicians with actionable, patient-specific insights.

5 Nov 2024

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

29 Oct 2024

Early intervention with TAVR proves safe and effective for asymptomatic aortic stenosis

The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).

29 Oct 2024

Research highlights importance of quality improvement programs in stroke care

New research published this month shows the key role quality improvement programs play in ensuring hospitals can adequately fight one of the biggest public health threats facing our country: stroke.

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

NYU Langone researchers address the challenges of heart failure in cancer patients

A new scientific statement issued today by the Heart Failure Society of America highlights a critical connection between heart failure (HF) and cancer, with shared mechanisms contributing to the incidence and progression of both diseases.

16 Oct 2024

How carnitine transporters boost reproductive health

Research uncovers the critical role of carnitine transporters in maintaining fertility by regulating energy metabolism and protecting reproductive cells from oxidative stress. It suggests new pathways for treating infertility through carnitine supplementation and targeted therapies.

6 Oct 2024

NIH awards grant to study how dilated cardiomyopathy progresses to heart failure

A University of Arizona College of Medicine – Phoenix researcher was recently awarded a $1.9 million National Institutes of Health grant to study the molecular mechanisms of how dilated cardiomyopathy progresses to heart failure, which could eventually lead to better preventive and treatment options for heart failure.

27 Sep 2024