Congenital Heart Disease News and Research

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New genetic discovery improves understanding of congenital heart disease

A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial growth.

21 Sep 2022

World's first partial heart transplant performed at Duke Health

A team at Duke Health has performed what is believed to be the world's first partial heart transplant, with the living arteries and valves from a freshly donated heart fused onto a patient's existing heart.

8 Sep 2022

Potential cause of racial disparity affecting infants with congenital heart disease discovered

Race was already known to matter when it came to health outcomes for infants with congenital heart disease (CHD), the most common birth defect, affecting 1 in 100 live births.

29 Aug 2022

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Earlier detection of pulmonary hypertension in the community and expedited referral of high-risk or complex patients are recommended in the European Society of Cardiology (ESC) and European Respiratory Society (ERS) Guidelines for the diagnosis and treatment of pulmonary hypertension, published online today in European Heart Journal and the European Respiratory Journal.

26 Aug 2022

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve damage caused by hereditary transthyretin amyloidosis, a rare disease that can be fatal without management.

18 Aug 2022

Study gains new insights into heart and lung conditions in babies born with Down Syndrome

A study from RCSI University of Medicine and Health Sciences has gained new insights into changes in heart function and blood pressure in the lungs of babies born with Down Syndrome.

16 Aug 2022

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

A new study reviews recent advancements made in the development of RSV immunoprophylactic measures.

11 Aug 2022

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

5 Aug 2022

Integrating mental health support with routine care is essential for people with congenital heart defects

Although many individuals born with congenital heart defects develop resilience and have a high quality of life, they may face a variety of health-related psychological and social challenges throughout their lives.

14 Jul 2022

Nitric oxide use in cardiopulmonary bypass surgery does not improve the recovery of children

Infants undergoing heart surgery are connected to a heart-lung machine and given nitric oxide as an anti-inflammatory.

27 Jun 2022

Reduced exercise capacity is common in long COVID patients

In a recent study posted to the medRxiv* preprint server, researchers illustrated cardiac findings in coronavirus disease 2019 (COVID-19)-recovered individuals more than a year after infection.

22 May 2022

Study validates long-term safety and efficacy of Harmony transcatheter pulmonary valve implant

A study of one year outcomes in the largest cohort to date of Harmony transcatheter pulmonary valve (TPV) patients with congenital heart disease (CHD) and severe pulmonary regurgitation (PR) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions 2022 Scientific Sessions.

19 May 2022

Children's Colorado first in the world to implant the newly FDA-approved G-Armor Stent

Children's Hospital Colorado (Children's Colorado) is the first hospital in the world to implant the newly FDA-approved G-Armor Stent. Although the stent is designed to be used in the smallest of patients, it was first implanted in a Colorado father of two.

18 May 2022

Combined use of traditional cigarettes and e-cigarettes does not reduce cardiovascular disease risk

People who use both traditional (combustible) cigarettes and e-cigarettes do not reduce their risk of cardiovascular disease compared to people who exclusively use traditional cigarettes, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

6 May 2022

ACNAP-EuroHeartCare Congress 2022: Latest evidence on how to optimize cardiovascular care

Discover how patients with heart disease can live well, be healthy, and live longer at ACNAP-EuroHeartCare Congress 2022, a scientific congress of the European Society of Cardiology (ESC).

6 May 2022

NIH awards $10.9 million COBRE grant to support Nemours Children's 'well beyond medicine' strategy

The National Institutes of Health (NIH) recently awarded a Phase 1, 5-year $10.9 million Center of Biomedical Research Excellence (COBRE) award, entitled Research Expanding Access to Child Health (REACH) Center to Anne Kazak, PhD, Enterprise Director, and Melissa Alderfer, PhD, Director of the Center for Healthcare and Delivery Science (CHDS) at Nemours Children's Health.

28 Apr 2022

Misexpression of non-cardiac genes may lead to congenital heart disease

Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

27 Apr 2022

Impaired brain growth in the womb can predict worsened infant neurodevelopmental outcomes

A new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes in infants with congenital heart disease.

22 Apr 2022

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

A recent scientific statement published in Circulation reviewed the current knowledge on COVID-19.

13 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022