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IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Further to a successful follow-up audit, IBBL (Integrated BioBank of Luxembourg) becomes the first biobank worldwide to be accredited for the next-generation 16S rRNA gene sequencing, a cutting-edge method that takes forward research into the human microbiome.

23 Dec 2016

UNIST study could open up new avenues of research in cancer treatment

The new study, by researchers from UNIST demonstrates a more holistic light-based treatment to nuke cancer cells instead of surgery. The results, reported in the September issue of the Journal of the American Chemical Society, could open up new avenues of research in cancer treatment.

14 Dec 2016

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN.

1 Dec 2016

IQWiG finds both hint of benefit and harm from corneal collagen cross-linking for keratoconus

In patients with keratoconus the cornea of the eye begins to bulge. So-called corneal collagen cross-linking aims to halt this process. In this procedure, the cornea is stiffened through locally applied vitamin B2 in combination with UVA radiation.

30 Nov 2016

Biochemists create first atlas of DNA-binding molecules for use in precision medicine

Biochemists at the University of Wisconsin-Madison have created the first atlas that maps where molecular tools that can switch genes on and off will bind to the human genome.

8 Nov 2016

Innovative procedure may improve outcomes in people with keratoconus

An innovative procedure may improve outcomes in people with a degenerative eye disease, suggest five-year results from a study presented at AAO 2016, the 120th annual meeting of the American Academy of Ophthalmology.

19 Oct 2016

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

The advanced phase of acute kidney injury can be fatal in even one in two patients. Fortunately, now it will be possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis good.

13 Oct 2016

Fraunhofer researchers plan to use electron beams to remove germs from tissue transplants

Medical products, packaging and food can be safely and efficiently sterilized with electron beams.

7 Sep 2016

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.

26 Aug 2016

Researchers reveal how bacterial cell wall adapts to threatening environments

Researchers at Umea University in Sweden have published new findings on the adaptation of the bacterial cell wall in the Journal of the American Chemical Society.

8 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that a plant-virus-based carrier successfully delivers a drug in vivo.

9 Jun 2016

Cryo-EM technique allows researchers to visualize large transcription PICs at near-atomic resolution

An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of California at Berkeley and Northwestern University.

12 May 2016

Simple, cheap chemical sensors may detect developing cancers in future

Many cancers could be successfully treated if the patient consulted the doctor sufficiently early. But how can a developing cancer be detected if it doesn't give rise to any symptoms? In the near future, suitably early diagnosis could be provided by simple and cheap chemical sensors - thanks to special recognizing polymer films developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw.

12 May 2016

Synthetic heart valve one step closer to reality

The quest for a synthetic heart valve that faithfully mimics the original is a step closer to its goal with the Rice University find that a natural polymer called hyaluronan, one of the chief components of skin and connective tissue, can serve as a versatile template for growing spongiosa, the middle tissue layer in the valve's leaflets.

12 May 2016

New light-based technique may offer improved treatment for eye problems

Researchers have developed a new light-based technique that selectively stiffens tissue in the cornea and might one day offer improved treatment for eye problems caused by weakened corneal tissue.

5 May 2016

Excess activation of LOX may play causative role in progression of cardiac failure

Heart failure is a progressive condition, where structural and functional alterations of the ventricle limit the ability of the heart to either fill or eject blood. There are approximately 550,000 new cases of heart failure each year with a prevalence of nearly 5 million; most patients die within five years of diagnosis.

2 Apr 2016

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Scientists have devised a triple-stage "cluster bomb" system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor.

30 Mar 2016

Newly developed biodegradable polymer grafts can help repair the spine

Remember those colorful "grow capsules" that blossom into animal-shaped sponges in water? Using a similar idea, scientists have developed biodegradable polymer grafts that, when surgically placed in damaged vertebrae, should grow to be just the right size and shape to fix the spinal column.

14 Mar 2016

Study on DNA scrunching may aid in developing new antimicrobial medicines

A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins to direct the synthesis of RNA. This finding may aid in the discovery of new antimicrobial medicines, and the powerful technological approaches developed for this research may shed light on other essential cellular processes.

4 Mar 2016

Cross Linking News and Research

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

UNIST study could open up new avenues of research in cancer treatment

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

IQWiG finds both hint of benefit and harm from corneal collagen cross-linking for keratoconus

Biochemists create first atlas of DNA-binding molecules for use in precision medicine

Innovative procedure may improve outcomes in people with keratoconus

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

Fraunhofer researchers plan to use electron beams to remove germs from tissue transplants

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

Researchers reveal how bacterial cell wall adapts to threatening environments

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

Cryo-EM technique allows researchers to visualize large transcription PICs at near-atomic resolution

Simple, cheap chemical sensors may detect developing cancers in future

Synthetic heart valve one step closer to reality

New light-based technique may offer improved treatment for eye problems

Excess activation of LOX may play causative role in progression of cardiac failure

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Newly developed biodegradable polymer grafts can help repair the spine

Study on DNA scrunching may aid in developing new antimicrobial medicines

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