Heroin News and Research

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Heroin is a very addictive chemical called diacetylmorphine. Heroin is a modified form of morphine, a highly abundant opium derived from the seedpods of the poppy plant.

CBD-based compounds boost the effects of naloxone

There's been a recent push in the U.S. to make naloxone - a fast-acting opioid antidote - available without a prescription.

28 Mar 2023

Reentry programs to help former prisoners obtain health care are often underused

When Matthew Boyd was released from a Georgia state prison in December 2020, officials sent him home without medicines he uses to manage chronic heart and lung conditions and high blood pressure, he said.

8 Mar 2023

Determining the role of the epigenetic enzyme, HDAC5, in an animal model

Substance use disorder (SUD) is an extremely difficult disorder to overcome, and many individuals with SUD return to regular use after repeated attempts to quit.

27 Feb 2023

Study finds fiftyfold increase in U.S. methamphetamine mortality rate between 1999 and 2021

The U.S. methamphetamine mortality rate increased fiftyfold between 1999 and 2021, with most of the added deaths also involving heroin or fentanyl, researchers report in the American Journal of Public Health.

20 Feb 2023

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Many people living on the streets in Philadelphia's Kensington neighborhood — the largest open-air drug market on the East Coast — are in full-blown addiction, openly snorting, smoking, or injecting illicit drugs, hunched over crates or on stoops. Syringes litter sidewalks, and the stench of urine fouls the air.

15 Feb 2023

NIH establishes research network to test harm reduction strategies in community settings

To address the overdose crisis in the United States, the National Institutes of Health has established a research network that will test harm reduction strategies in different community settings to inform efforts to help save lives.

16 Dec 2022

New chemical compound shows promise to reverse effects of potentially deadly drugs

Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020 - more than five times the number of deaths in the year 2000 - and synthetic opioids like fentanyl are one of the main culprits.

16 Dec 2022

Study finds spike in endocarditis among patients with cocaine or opioid use disorder from 2011 to 2022

The incidence rate of infective endocarditis - a rare but often fatal inflammation of the heart valves - among patients with cocaine use disorder or opioid use disorder increased from 2011 to 2022, with the steepest increase occurring from 2021 to 2022, a new study reports.

13 Dec 2022

In rural America, deadly costs of opioids outweigh the dollars tagged to address them

Tim Buck knows by heart how many people died from drug overdoses in his North Carolina county last year: 10. The year before it was 12 — an all-time high.

12 Dec 2022

Drug overdose deaths reach a record high among pregnant and postpartum women, study reveals

Drug overdose deaths among pregnant and postpartum women increased more than 180 percent in the past five years, according to a new study conducted at Columbia University Mailman School of Public Health.

6 Dec 2022

Addiction treatment proponents urge rural clinicians to pitch in by prescribing medication

Andrea Storjohann is glad to see that she's becoming less of a rarity in rural America.

1 Dec 2022

Schools, sheriffs, and syringes: State plans vary for spending $26B in opioid settlement funds

With more than 200 Americans still dying of drug overdoses each day, states are beginning the high-stakes task of deciding how to spend billions of dollars in settlement funds from opioid manufacturers and distributors.

22 Nov 2022

New fentanyl vaccine could prevent deadly opioid from entering the brain

A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug's "high."

14 Nov 2022

Fentanyl in high school: A Texas community grapples with the reach of the deadly opioid

The hallways of Lehman High School looked like any other on a recent fall day. Its 2,100 students talked and laughed as they hurried to their next classes, moving past walls covered with flyers that advertised homecoming events, clubs, and football games.

10 Nov 2022

Hospitals have been slow to bring on addiction specialists

In December, Marie, who lives in coastal Swampscott, Massachusetts, began having trouble breathing. Three days after Christmas, she woke up gasping for air and dialed 911.

11 Oct 2022

Specific brain circuit initially implicated in animals found to be impaired in people with cocaine or heroin addiction

White matter in the brain that was previously implicated in animal studies has now been suggested to be specifically impaired in the brains of people with addiction to cocaine or heroin, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and Baylor College of Medicine.

6 Oct 2022

Star-shaped brain cells can "turn off" neurons involved in heroin relapse

Neuroscientists from the Medical University of South Carolina report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin.

5 Oct 2022

Artificial intelligence tools speed up the process of identifying people who inject drugs

An automated process that combines natural language processing and machine learning identified people who inject drugs (PWID) in electronic health records more quickly and accurately than current methods that rely on manual record reviews.

22 Sep 2022

High-quality human clinical trials needed to determine the benefits of CBD for heart disease patients

As cannabidiol (CBD) use rises, high quality randomized clinical trials are needed to determine if anti-inflammatory benefits of CBD for heart disease seen in preclinical data will work in a real-world setting, according to research presented at ACC Latin America 2022 Together with CardioAcademic.

5 Sep 2022

A needle exchange project modeled on urban efforts aims to save lives in rural Nevada

Richard Cusolito believes he's saving lives by distributing clean syringes and needles to people who use drugs in this rural area of northeastern Nevada — but he knows some residents disagree.

24 Aug 2022