OCT News and Research

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Blocking immune cell signals reduces scar tissue formation in wounds

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

25 Nov 2025

AI-powered tool improves object detection for visually impaired users

Over the last few years, systems and applications that help visually impaired people navigate their environment have undergone rapid development, but still have room to grow, according to a team of researchers at Penn State.

25 Nov 2025

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.

25 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Study reveals metabolic benefits of reducing ultra-processed foods in older adults

A controlled feeding study out of South Dakota State University shows that older adults who ate fewer ultra-processed foods naturally consumed fewer calories, lost weight and abdominal fat, and showed improvements in insulin, nutrient-sensing hormones, and inflammation.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

New method can stop or reverse the decline of cellular energy production

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production - a finding that could have revolutionary effects across medicine.

22 Nov 2025

Study uncovers role of mechanical forces in human gastrulation

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

22 Nov 2025

What to know about the CDC’s baseless new guidance on autism

The rewriting of a page on the CDC's website to assert the false claim that vaccines may cause autism sparked a torrent of anger and anguish from doctors, scientists, and parents who say Health and Human Services Secretary Robert F. Kennedy Jr. is wrecking the credibility of an agency they've long relied on for unbiased scientific evidence.

22 Nov 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Oral arginine reduces amyloid buildup in Alzheimer’s models

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their clinical effectiveness remains limited.

21 Nov 2025

Study shows gluten sensitivity is driven by gut–brain interactions rather than gluten

A landmark study has revealed that gluten sensitivity, which affects approximately 10 per cent of the global population, is not actually about gluten but part of the way the gut and brain interact.

21 Nov 2025

Understanding how and when AI technology could help clinicians save lives

While artificial intelligence technology is increasingly being used - formally and informally - to support medical diagnoses, its utility in emergency medical settings remains an open question.

20 Nov 2025

Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

Ischemic stroke, a leading cause of disability and mortality worldwide, is a complex cerebrovascular event with outcomes heavily influenced by the inflammatory response.

20 Nov 2025

C-reactive protein shows stronger accuracy for early-onset sepsis in preterm newborns

Neonatal EOS, a severe bloodstream infection that strikes within the first three days of life, is a major cause of infant illness and death worldwide.

20 Nov 2025

Scientists uncover molecular mechanism behind chemotherapy-induced peripheral neuropathy

Chemotherapy activates a stress sensor in immune cells, triggering inflammation and nerve damage, which may help explain why many cancer patients experience debilitating pain as a side effect, according to a new study by Weill Cornell Medicine and Wake Forest University School of Medicine researchers

20 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

Study develops highly accurate polygenic risk models tailored for Han Chinese populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

20 Nov 2025

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer.

20 Nov 2025

Maternal age drives embryo arrest independently of chromosomal errors

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled "Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos."

20 Nov 2025

OCT News and Research

Blocking immune cell signals reduces scar tissue formation in wounds

AI-powered tool improves object detection for visually impaired users

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Infection-related hospital stays linked to higher risk of developing dementia

Study reveals metabolic benefits of reducing ultra-processed foods in older adults

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

New method can stop or reverse the decline of cellular energy production

Study uncovers role of mechanical forces in human gastrulation

What to know about the CDC’s baseless new guidance on autism

Immune system abnormalities identified as core mechanism in major depressive disorder

Oral arginine reduces amyloid buildup in Alzheimer’s models

Study shows gluten sensitivity is driven by gut–brain interactions rather than gluten

Understanding how and when AI technology could help clinicians save lives

Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

C-reactive protein shows stronger accuracy for early-onset sepsis in preterm newborns

Scientists uncover molecular mechanism behind chemotherapy-induced peripheral neuropathy

Changes in brain fats play a key role in Alzheimer's development and progression

Study develops highly accurate polygenic risk models tailored for Han Chinese populations

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

Maternal age drives embryo arrest independently of chromosomal errors

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