Synthetic Biology News and Research

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Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

A novel approach to photosynthetic production of high-value compounds

Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucose or glycerol. By engineering photosynthetic cyanobacteria to live symbiotically inside yeast cells, the bacteria-yeast hybrids can produce important hydrocarbons, paving new biotechnical pathways to non-petroleum-based energy, other synthetic biology applications, and the experimental study of evolution.

27 Aug 2024

Advancements in neoantigen vaccines offer hope for personalized cancer therapy

The saga of cancer treatment is marked by a relentless pursuit of effectiveness against a disease characterized by complexity and adaptability.

19 Aug 2024

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

9 Aug 2024

Asimov introduces its AI-driven 4th generation CHO Edge System with increased titer guarantee

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced the launch of its fourth generation CHO Edge System.

From Asimov 31 Jul 2024

Novel method enables RNA detection with Cas12 nucleases

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

Harnessing cell's natural delivery system for targeted drug delivery

Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs - molecules like proteins, RNA and combinations of the two - to specific diseased parts of the body.

17 Jul 2024

Enzymatic RNA synthesis paves the way for sustainable therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

12 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Northwestern researchers propose scalable framework for synthetic biology education

The field of synthetic biology, the science of manipulating biology, has a lot of "cooks in the kitchen," which has both helped it flourish and made it unusually difficult to create a cohesive, consistent curriculum for students at every level of study.

28 Jun 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024

Novel approach can make many more bacteria amenable to genetic engineering

Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species.

26 Jun 2024

New approach reduces the required drug dosage for cancer treatment

Traditional chemotherapy often poses significant challenges, including severe side effects, damage to healthy tissue and limited efficacy.

6 Jun 2024

Sphere Fluidics launches Cyto-CellectPLUS to accelerate cell line development workflows

Next-generation assay provides a rapid and cost-effective solution to quantify IgG production in single cells.

From Fluidic Sciences and Sphere Bio 4 Jun 2024

New frontiers in medicine: COVID-19 lessons push for multidisciplinary collaboration

Researchers highlight the need for multidisciplinary collaboration in medicine, especially in addressing transmissible illnesses, precision medicine, and data science, as learned from the COVID-19 pandemic.

28 May 2024

ERS Genomics appoints John E Milad as Chief Executive Officer

ERS Genomics Limited (‘ERS’), the CRISPR licensing company, today announced the appointment of John E Milad as CEO, with immediate effect. John brings over 25 years of experience as an executive leader, venture capitalist, and investment banker focused on the life sciences and medical technology sectors.

From ERS Genomics 13 May 2024

Synthetic Biology News and Research

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

A novel approach to photosynthetic production of high-value compounds

Advancements in neoantigen vaccines offer hope for personalized cancer therapy

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

Asimov introduces its AI-driven 4th generation CHO Edge System with increased titer guarantee

Novel method enables RNA detection with Cas12 nucleases

Harnessing cell's natural delivery system for targeted drug delivery

Enzymatic RNA synthesis paves the way for sustainable therapeutics

Protein nanocages: A promising frontier in mRNA therapeutics

Northwestern researchers propose scalable framework for synthetic biology education

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Novel approach can make many more bacteria amenable to genetic engineering

New approach reduces the required drug dosage for cancer treatment

Sphere Fluidics launches Cyto-CellectPLUS to accelerate cell line development workflows

New frontiers in medicine: COVID-19 lessons push for multidisciplinary collaboration

ERS Genomics appoints John E Milad as Chief Executive Officer

Sphere Fluidics appoints Dale Levitzke as Chief Executive Officer

Beckman Coulter Life Sciences and Watchmaker Genomics Collaborate to Deliver NGS Library Preparation Solutions

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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