Thrombus News and Research

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A blood clot or thrombus, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors).

CMR could offer complete imaging solution before pulmonary vein isolation

Cardiac magnetic resonance can potentially be used to detect thrombi at the same time as being used for pulmonary venous anatomy mapping, say researchers

4 Jun 2016

Increased fitness can normalize platelet function quickly

Women with poor physical fitness display significantly higher platelet activation than women with average to very good fitness. That is the major finding of a study of 62 young women, conducted by the research groups of Ivo Volf and Rochus Pokan and sponsored by the Austrian Heart Foundation. Platelet (thrombocyte) activation can lead to the formation of potentially life-threatening blood clots.

3 May 2016

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These complications are thought to be secondary to elevated central venous pressure, chronic venous congestion and low cardiac output.

29 Apr 2016

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Renal cell carcinoma can sometimes spread to the inferior vena cava (IVC), the body's largest vein, posing a threat to the heart and brain. Robotic nephrectomy for inferior vena cava tumor thrombus has favorable outcomes in selected patients compared with open surgery, which can have a high rate of complications, report surgeons in The Journal of Urology.

8 Feb 2016

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs.

29 Jan 2016

Upstate Medical University physicians use minimally invasive robotic surgery in complex IVC thrombus case

Physicians at Upstate Medical University in Syracuse describe in the December issue of Urology the first case ever in which doctors used minimally invasive robotic surgery to perform a radical nephrectomy (removal of entire kidney) with a level III inferior vena cava thrombectomy (removal of a tumor from the largest vein that carries blood to the heart).

27 Jan 2016

New model of arterial thrombus formation is similar to popular video game

A group of biophysicists, including representatives from MIPT, has developed a mathematical model of arterial thrombus formation, which is the main cause of heart attacks and strokes.

1 Dec 2015

Boston Scientific obtains FDA approval, CE Mark for AngioJet ZelanteDVT catheter to treat DVT

Boston Scientific has received United States (U.S.) Food and Drug Administration approval and CE Mark for the AngioJet ZelanteDVT thrombectomy catheter to treat deep vein thrombosis (DVT) in large-diameter upper and lower limb peripheral veins.

30 Nov 2015

Meta-analysis backs thrombectomy over standard stroke care

A meta-analysis published in JAMA confirms that stroke patients can achieve better functional outcomes after mechanical thrombectomy than after intravenous tissue plasminogen activator alone.

5 Nov 2015

Review of haemodynamics in stent development shows spiral flow may be key to improving peripheral arterial stent performance

Vascular Flow Technologies, the medical device company using proprietary Spiral Laminar Flow (SLF™) technology to replicate natural blood flow for enhanced patient outcomes, today announces that 'Haemodynamics and Flow Modification Stents for Peripheral Arterial Disease: A Review’, co-authored by VFT’s non-executive Medical Director Graeme Houston, has been published in the Annals of Biomedical Engineering. The paper reviews the importance of haemodynamics in stent development as a method of improving patency and longevity of the stent.

4 Nov 2015

New tool may help identify high risk atherosclerotic plaques

Researchers have developed and validated a new tool to help identify unstable or high risk atherosclerotic plaques--inflamed fatty deposits in the artery wall and a main contributor to cardiovascular disease (CVD). This breakthrough may lead to better identifying which plaques are considered at the highest risk for rupturing and causing a heart attack or stroke.

14 Oct 2015

New approach helps create virtual models for treating abdominal aortic aneurysms

Virtual models can be created in the angiography room thanks to an approach developed by researchers at the University of Montreal Hospital Research Centre and the university's departments of radiology, radiation oncology, and nuclear medicine. The latest advances were presented by Dr. Gilles Soulez at the Cardiovascular and Interventional Radiology Society of Europe conference on September 27, 2015.

8 Oct 2015

Acute Cardiovascular Care 2015 to be held in Vienna from 17 to 19 October

Acute Cardiovascular Care 2015 will highlight innovations and controversies in the field, guaranteeing great stories on topics relevant to the press.

18 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Retrieval of larger thrombi during intra arterial treatment (IAT) is associated with improved neurological recovery after acute ischaemic stroke, according to a sub study of the MR CLEAN trial presented at ESC Congress today by Dr Anouchska Autar, PhD candidate at the Erasmus Medical Centre in Rotterdam, the Netherlands.

1 Sep 2015

PRESTIGE study suggests novel target to prevent stent thrombosis

Recruitment of leukocytes is a hallmark of stent thrombosis, according to results from the PRESTIGE study presented today at ESC Congress and published in European Heart Journal. The findings suggest that immune cell mediated thrombotic processes may be a realistic target for novel therapies to prevent stent thrombosis.

1 Sep 2015

Symic receives $1.5M NIH Phase II SBIR grant to develop AVF therapeutic candidate

Platform therapeutic company Symic Biomedical, Inc. announced today that it has received a $1.5M Phase II SBIR grant from the National Institutes of Health to further develop its therapeutic agent to reduce arteriovenous fistula (AVF) failures, a significant unmet clinical need in end stage renal disease (ESRD) patients undergoing hemodialysis.

27 Aug 2015

Neovasc's second quarter revenues drop 18%

Neovasc Inc. today announced financial results for the quarter ended June 30, 2015.

6 Aug 2015

Surgeons describe positive outcomes in kidney cancer patients treated with robotic IVC thrombectomy

Surgery is required when cancer of the kidney causes a Level III thrombus, or clot, to develop in the major vein leading back to the heart. Traditionally this complicated procedure, inferior vena cava (IVC) thrombectomy, is performed using a large open incision, primarily because the vein is often difficult to reach.

30 Jul 2015

Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

The National Institute for Health and Care Excellence has recommended a new treatment to help patients suffering from blood clots in the legs and lungs.

13 Jul 2015

Thrombus News and Research

Further Reading

CMR could offer complete imaging solution before pulmonary vein isolation

Increased fitness can normalize platelet function quickly

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

Upstate Medical University physicians use minimally invasive robotic surgery in complex IVC thrombus case

New model of arterial thrombus formation is similar to popular video game

Boston Scientific obtains FDA approval, CE Mark for AngioJet ZelanteDVT catheter to treat DVT

Meta-analysis backs thrombectomy over standard stroke care

Review of haemodynamics in stent development shows spiral flow may be key to improving peripheral arterial stent performance

New tool may help identify high risk atherosclerotic plaques

New approach helps create virtual models for treating abdominal aortic aneurysms

Acute Cardiovascular Care 2015 to be held in Vienna from 17 to 19 October

SLU scientist receives grant to solve blood-clotting mysteries

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

PRESTIGE study suggests novel target to prevent stent thrombosis

Symic receives $1.5M NIH Phase II SBIR grant to develop AVF therapeutic candidate

Neovasc's second quarter revenues drop 18%

Surgeons describe positive outcomes in kidney cancer patients treated with robotic IVC thrombectomy

Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

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