Toxin News and Research

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Unfolded protein response disruptions contribute to colorectal cancer and gut-related disorders

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

20 Feb 2025

Hydrodissection may offer hope for post-amputation pain relief

A reliable method to treat post-amputation pain remains elusive, but a new Northwestern Medicine study conducted in collaboration with Ukrainian physicians suggests that hydrodissection - a simple procedure that injects fluid around nerves - may reduce residual limb pain and opioid dependence.

19 Feb 2025

Protein shuttling mechanism enables bacteria to survive exposure to antibiotics

A Cornell University-led collaboration has uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum of antibiotics along with other physiological substrates from the cell.

13 Feb 2025

Electrical activity drives aggression in small cell lung cancer

Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their own electric network, like that seen in the body's nervous system.

12 Feb 2025

Nanoscale plastic particles enhance toxin uptake in plants and human cells

Micro- and nanoscale plastic particles in soil and water can significantly increase how much toxic chemicals plants and human intestinal cells absorb, according to two new studies from Rutgers Health that raise fresh concerns about food safety from plastic pollution.

11 Feb 2025

Study reveals how beneficial gut microbe breaks down mucus for health

A microbe found in the lower part of the gut that is associated with good health has been comprehensively analyzed and found to have a focused diet breaking down sugars locked away in mucus.

31 Jan 2025

Exploring the use of genomic classifier tests in prostate cancer risk stratification

A systematic review found that while genomic classifier (GC) tests may influence risk classifications or treatment decisions for patients with localized prostate cancer (PCa), there is a need for better data on their cost-effectiveness, clinical utility, and their impact on racial and ethnic groups, particularly Black men.

20 Jan 2025

Researchers utilize mosquito mating to spread malaria-fighting fungi

Researchers have developed genetically modified fungi that can kill malaria-transmitting mosquitoes through sexual transmission, offering a promising solution to target both indoor and outdoor populations.

19 Jan 2025

Antihistamine shows promise for treating rare genetic liver disease

A common antihistamine may offer hope for patients with a rare genetic disease that can lead to severe liver damage and ultimately require transplantation, according to new research from Rutgers Health.

16 Jan 2025

Fruit flies steal bacterial defense to survive parasitic wasps

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

24 Dec 2024

Hippocampal inflammation affects behavior differently in males and females

Inflammation in the hippocampus – the brain's memory centre – significantly alters motivation and behavior in mice, including food-seeking behaviour, with notable differences between males and females, a recent study reveals.

18 Dec 2024

Skin-friendly bacteria could revolutionize vaccination

Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles.

11 Dec 2024

Mouse study links glyphosate to Alzheimer's-like brain changes and anxiety

Glyphosate exposure in mice exacerbates Alzheimer's-like neuropathologies, increases neuroinflammation, and leaves lasting effects, even after prolonged recovery.

9 Dec 2024

Bacterial toxin may fuel colorectal cancer metastasis

A toxin in the bacteria that's one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study led by UF Health Cancer Center researchers and international collaborators has found.

6 Dec 2024

E.coli toxin-producing bacteria linked to bladder and bowel cancer

Certain intestinal bacteria are found more frequently in countries such as Norway than in a number of other countries and there is also a higher incidence of bladder cancer, bowel cancer and prostate cancer.

6 Dec 2024

New insights into how aging affects muscle cell regeneration

As muscles age, their cells lose the ability to regenerate and heal after injury. Now, Cornell University researchers have created the most comprehensive portrait to date of how that change, in mice, unfolds over time.

2 Dec 2024

Anxiety and negative emotions reduced by brain circuit that consciously slows breathing

Findings on the dACC→PnC circuit show how breathing patterns influence anxiety, paving the way for new therapeutic approaches to emotional regulation.

22 Nov 2024

Exploring mouse models for studying liver fibrosis regression

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol abuse, and viral hepatitis.

8 Nov 2024

How bacteria trigger colon cancer

Investigation shows how bacterial adhesins contribute to colon cancer mutations, suggesting new avenues for therapeutic intervention in colorectal cancer.

7 Nov 2024

Study uncovers how certain E. coli bacteria in the gut promote colon cancer

Scientists have uncovered how certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin.

6 Nov 2024