Tumor Necrosis Factor Alpha News and Research

RSS

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Pertussis vaccination responses in COPD patients

Researchers evaluated the humoral and cellular immune responses to pertussis vaccination in COPD patients.

21 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

Researchers present the mechanisms by which SARS-CoV-2 could infect the brain and affect memory.

5 Jul 2023

Are a high-refined carbohydrate diet and the alterations resulting from its intake linked to small intestine changes?

Researchers investigated whether a high-refined carbohydrate diet and associated metabolic alterations could cause small intestinal dysregulation.

27 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin, a widely available oral medication, reduces SARS-CoV-2 viral load by 3.6-fold in outpatient trial, offering a potential treatment option. Ivermectin and fluvoxamine show no significant virologic effect.

12 Jun 2023

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.

9 Jun 2023

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Taurine and black pepper, along with key terpene constituents, are investigated for their potential in reducing cardiovascular risk factors and combating related diseases in this comprehensive literature review. Their cardioprotective effects and mechanisms are explored.

31 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Can intermittent fasting tackle obesity-related inflammation?

Research reviews the effects of two forms of intermittent fasting, time-restricted eating (TRE) and alternate-day fasting (ADF), on body weight and key circulating inflammatory markers (CRP, TNF-alpha, and IL-6) in adults with obesity. The results suggest that intermittent fasting has little or no effect on key inflammatory markers, but more research is needed to confirm these findings.

8 May 2023

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Researchers evaluated whether edible mushrooms aid in preventing neurodegenerative diseases.

18 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023