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Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

A new study aimed to develop a standardized protocol for SARS-CoV-2 RNA detection in semen fractions used for assisted reproductive technology.

26 Oct 2022

What is the efficacy of mulberry component Kuwanon C against COVID-19?

A recent study determined the underlying antiviral mechanism of KC associated with the inhibition of SARS-CoV-2.

24 Oct 2022

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Researchers evaluated imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Analyses of 11 commercially available PCR kits to detect monkeypox virus DNA

In a recent study posted to the medRxiv* server, researchers in Germany and Switzerland evaluated 11 commercial reverse transcription-polymerase chain reaction (RT-PCR) kits (A to L) for Monkeypox virus (MPXV) detection.

23 Oct 2022

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Researchers evaluate SARS-CoV-2 vaccine-induced immune responses in SARS survivors.

23 Oct 2022

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Researchers explore whether FebriDx could differentiate between bacteria- and virus-induced immune responses during acute respiratory infection.

23 Oct 2022

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Researchers demonstrated the structural basis of how the receptor-binding domain nested Omicron mutations have adapted to mouse angiotensin-converting enzyme 2 rather than human ACE2.

22 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

Why do some people attract mosquitoes more than others?

Mosquitoes (e.g., Aedes aegypti) are common vectors for many viruses that infect the human population, such as dengue, Zika, and yellow fever.

19 Oct 2022

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

Differential effects of SARS-CoV-2 variants on children and adolescents

A recent Emerging Infectious Diseases journal study evaluated whether specific SARS-CoV-2 variants were linked with different clinical manifestations in children and adolescents.

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Assay News and Research

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

What is the efficacy of mulberry component Kuwanon C against COVID-19?

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

A novel approach for viral genomic surveillance

Analyses of 11 commercially available PCR kits to detect monkeypox virus DNA

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Are pediatric COVID-19 samples less infectious?

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Why do some people attract mosquitoes more than others?

SARS-CoV-2 transmission from infected owner to pet rats

Differential effects of SARS-CoV-2 variants on children and adolescents

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

eBook: Using iPSCs models for human disease research and drug discovery eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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