Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Scientists engineer silkworms to produce different variants of adhesion molecules

Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

These findings should have a significant impact on future vaccination strategies and pave the way for new treatments of an underperforming or over-reacting immune system. The results of this research are published in Cell Stem Cell on March 12, 2020.

13 Mar 2020

Mayo Clinic study uncovers stem cell-activated mechanisms of healing after heart attack

Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work.

12 Mar 2020

Scientists receive €2.45 million funding for leukemia research

Leukemia stem cells are considered to be the starting point of leukemia; their elimination is a basic prerequisite for a successful long-term therapy. Scientists at Heidelberg University Hospital, the Heidelberg Institute for Stem Cell Technology and Experimental Medicine at the German Cancer Research Center, the German Cancer Research Center and the European Molecular Biology Laboratory have now obtained research funding of €2.45 million from the German Federal Ministry of Education and Research as part of the junior research alliance LeukoSyStem.

11 Mar 2020

Crushed by a hospital bill? Stand up for yourself

The cost of medical treatment depleted Frances Edwards' savings after she was diagnosed with stage 3 melanoma in October 2016 — even though she has insurance.

11 Mar 2020

Genetic test could help doctors to identify patients with ultra high risk multiple myeloma

A new genetic test could help doctors pick out patients with the bone marrow cancer multiple myeloma who are at 'ultra high risk' of their cancer progressing aggressively early on.

10 Mar 2020

Study identifies a mutation that triggers deadly amyloidosis

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains.

10 Mar 2020

The second person cured from HIV goes public

In the 1980s and early 1990s, the outbreak of HIV and AIDS swept across the globe. Today, more than 70 million people have been infected with HIV, and about 35 million have died from AIDS since the start of the pandemic. However, scientific advances, such as the development of antiretroviral drugs, have enabled people with access to treatment to live long and healthy lives with HIV. But, there is still no vaccine and cure for it. In history, only two persons have been cleared of the infection, one in Berlin and now the second one in London.

10 Mar 2020

Researchers uncover creeping, crawling origin of MYH9-related blood disorders

Ouch, you've cut your finger! As you fumble to grab a tissue, the paramedics in your blood are already rushing to the scene.

9 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

Researchers with Nemours Children's Health System utilized Next Generation Sequencing (NGS) to more precisely identify genomic characteristics of leukemias in children, the most common childhood cancer.

5 Mar 2020

UConn team discovers a population of stem cells with ability to generate new bone

A population of stem cells with the ability to generate new bone has been newly discovered by a group of researchers at the UConn School of Dental Medicine.

5 Mar 2020

City Of Hope builds cloud-based data commons platform for observational study

A $12 million federal grant enabled City of Hope and collaborators to deploy a novel cloud-computing platform, making an immense amount of data from a historic 25-year study more accessible and user-friendly.

5 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

Eating less prolongs life

A new study published in the journal Cell in February 2020 reports that eating less is associated with better immunity, reduce inflammation all over the body, and reduced odds of diseases related to old age, as well as increasing the odds of living longer.

27 Feb 2020

Stem cell discovery could open the door to new approach for bone marrow transplantation

Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study being published on February 27 in Cell Stem Cell.

26 Feb 2020

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

Research from Rutgers Cancer Institute of New Jersey shows administering the immunotherapy drug pembrolizumab together with chemotherapy given at the same time as radiation treatment (chemoradiation) is safe and tolerable as a first-line therapy for patients with stage 3 non-small cell lung cancer.

21 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

Breakthrough discovery could open up new treatments for some blood cancers

Reversing runaway inflammation in the bone marrow could lead to major breakthroughs in treatments for some blood cancers, according to a new publication by scientists at Hackensack Meridian Health's Center for Discovery and Innovation.

16 Feb 2020

Bone Marrow News and Research

Further Reading

Scientists engineer silkworms to produce different variants of adhesion molecules

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

Mayo Clinic study uncovers stem cell-activated mechanisms of healing after heart attack

Scientists receive €2.45 million funding for leukemia research

Crushed by a hospital bill? Stand up for yourself

Genetic test could help doctors to identify patients with ultra high risk multiple myeloma

Study identifies a mutation that triggers deadly amyloidosis

The second person cured from HIV goes public

Researchers uncover creeping, crawling origin of MYH9-related blood disorders

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

UConn team discovers a population of stem cells with ability to generate new bone

City Of Hope builds cloud-based data commons platform for observational study

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

Eating less prolongs life

Stem cell discovery could open the door to new approach for bone marrow transplantation

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

New 3D model shows how breast cancer cells interact with the body’s stem cells

Breakthrough discovery could open up new treatments for some blood cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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