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New research identifies protein that controls formation of different types of mature blood cells

New research in the Journal of Experimental Medicine identifies a protein that controls the formation of different types of mature blood cells - a finding that could be important to developing new treatments for blood diseases and helping realize the potential of regenerative medicine.

8 Oct 2013

Study identifies new potential genetic culprits in origins of congenital heart defects

Mitochondria are the power plants of cells, manufacturing chemical fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in ridding the body of old or damaged cells.

5 Oct 2013

Researchers identify new prospects for developing cancer therapies

By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases.

1 Oct 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

Genes in mitochondria shape each person's risk for heart disease and diabetes

Genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's risk for heart disease and diabetes, according to a study published recently by researchers at the University of Alabama at Birmingham in the Biochemical Journal.

27 Sep 2013

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Sixty years ago scientists could electrically stimulate a region of a mouse's brain causing the mouse to eat, whether hungry or not. Now researchers from UNC School of Medicine have pinpointed the precise cellular connections responsible for triggering that behavior.

27 Sep 2013

Odour of newborns activates neural reward circuit in mothers, elicits maternal care functions

What woman has not wanted to gobble up a baby placed in her arms, even if the baby is not hers? This reaction, which everyone has noticed or felt, could have biological underpinnings related to maternal functions.

23 Sep 2013

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.

21 Sep 2013

An in-depth approach to examine placebo effect and its impact on doctor-patient relationship

The findings of a comprehensive review of the placebo phenomenon and its consequences for clinical medicine are contained in a new article, "Placebo and the New Physiology of the Doctor-Patient Relationship," (http://bit.ly/14QfSur) published in Physiological Reviews.

20 Sep 2013

Brain's white matter may determine susceptibility to chronic pain

The structure of the brain may predict whether a person will suffer chronic low back pain, according to researchers who used brain scans. The results, published in the journal Pain, support the growing idea that the brain plays a critical role in chronic pain, a concept that may lead to changes in the way doctors treat patients.

18 Sep 2013

Abnormalities in brain axons predispose people to chronic back pain after injury

Abnormalities in the structure of the brain predispose people to develop chronic pain after a lower back injury, according to new Northwestern Medicine- research. The findings could lead to changes in the way physicians treat patients' pain.

18 Sep 2013

Discovery sheds light on boundaries between brain regions

If the violins were taken away from the musicians performing Beethoven's 9th symphony, the resulting composition would sound very different. If the violins were left on stage but the violinists were removed, the same mutant version of the symphony would be heard.

13 Sep 2013

Love Hormone May Play Role In Autism

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12 Sep 2013

Neuroscientists honored for research into brain's reward and decision-making systems

Maximum reward, minimum punishment: these are the maxims humans and animals often apply when making decisions. A network of nerve cells in the brain conveys gratification.

12 Sep 2013

Neurobiologists create specific memories by direct manipulation of brain

By studying how memories are made, UC Irvine neurobiologists created new, specific memories by direct manipulation of the brain, which could prove key to understanding and potentially resolving learning and memory disorders.

11 Sep 2013

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.

11 Sep 2013

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

A little STING could go a long way in helping treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis, researchers report.

10 Sep 2013

Researchers investigate importance of STAT1 phosphorylation in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens.

7 Sep 2013

TSRI scientists identify involvement of angiomotin protein in cancer

A team led by scientists from The Scripps Research Institute have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth.

6 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Cell Nucleus News and Research

New research identifies protein that controls formation of different types of mature blood cells

Study identifies new potential genetic culprits in origins of congenital heart defects

Researchers identify new prospects for developing cancer therapies

Study indicates that RNA translation is dictated by translational hotspots

Genes in mitochondria shape each person's risk for heart disease and diabetes

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Odour of newborns activates neural reward circuit in mothers, elicits maternal care functions

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

An in-depth approach to examine placebo effect and its impact on doctor-patient relationship

Brain's white matter may determine susceptibility to chronic pain

Abnormalities in brain axons predispose people to chronic back pain after injury

Discovery sheds light on boundaries between brain regions

Love Hormone May Play Role In Autism

Neuroscientists honored for research into brain's reward and decision-making systems

Neurobiologists create specific memories by direct manipulation of brain

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

Researchers investigate importance of STAT1 phosphorylation in NK cells

TSRI scientists identify involvement of angiomotin protein in cancer

Locus coeruleus plays major role in learning, memory and other cognitive functions

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