Clinical Trial News and Research

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Breakthrough gene therapy reverses genetic deafness across age groups

Using gene therapy to treat hereditary deafness is safe and effective in both children and adults, according to new findings from a multicenter clinical trial.

22 Jul 2025

Cannabis and psychedelics rated most effective for symptom relief by eating disorder patients

A pioneering international survey of people living with eating disorders has found that cannabis and psychedelics, such as 'magic mushrooms' or LSD, were best rated as alleviating symptoms by respondents who self-medicated with the non-prescribed drugs.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Amid PFAS fallout, a Maine doctor navigates medical risks with her patients

When Lawrence and Penny Higgins of Fairfield, Maine, first learned in 2020 that high levels of toxic chemicals called PFAS taint their home's well water, they wondered how their health might suffer.

22 Jul 2025

Walking faster offers a simple solution to age-related frailty

Older adults who are prefrail or frail can increase their walking cadence through structured interventions, leading to significant gains in physical function. A rise in steps per minute was closely linked to meaningful improvements in walking endurance.

21 Jul 2025

Prime editing reverses symptoms of severe childhood neurological disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

21 Jul 2025

Combination of two cancer drugs could treat the most common form of dementia

A study comparing the gene expression signature of Alzheimer's disease with those elicited by 1,300 approved drugs found a combination of two cancer medications that could treat the most common form of dementia.

21 Jul 2025

Microbial therapy uses modified bacteria to target oxalate in the gut

Engineered gut bacteria designed to treat kidney stones successfully colonized the gut microbiome and reduced oxalate levels in animal models and early clinical trials in humans, researchers report.

18 Jul 2025

New mRNA vaccine strategy awakens immune system to fight cancer

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

18 Jul 2025

Heart failure and atrial fibrillation at the time of mitral valve repair linked to worse outcomes

Patients with heart failure and atrial fibrillation (AF) at the time of mitral transcatheter edge-to-edge repair (M-TEER) for severe mitral regurgitation are more than twice as likely to die or be rehospitalized for heart failure, compared to patients without AF.

18 Jul 2025

Study recommends ondansetron for children with gastroenteritis-induced vomiting at home

Most children seeking emergency department (ED) care due to vomiting are discharged home. Although they usually feel better when they leave the ED, the vomiting recurs in nearly one-third of children.

18 Jul 2025

AI-guided patient stratification boosts Alzheimer’s trial outcomes and efficiency

Scientists have used an AI model to reassess the results of a completed clinical trial for an Alzheimer's disease drug.

17 Jul 2025

New surgical method could become an alternative for treating groin hernias in women

In a study conducted in Uganda and published in JAMA Surgery, researchers from Karolinska Institutet evaluated a new surgical method for treating groin hernias in women.

17 Jul 2025

Nighttime avocado snack may support heart health in prediabetic adults

Findings from a newly published randomized controlled trial offer surprising insights for the one in three adults at greater risk of heart disease because of prediabetes.

17 Jul 2025

New data confirms efficacy of mitochondrial donation in preventing disease

The UK's pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has seen eight babies born, published research shows.

17 Jul 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

Fred Hutch leads national study on multi-cancer detection blood tests

Fred Hutch Cancer Center is leading the newly launched Vanguard Study, a national study of a new type of blood test that screens for several different cancers called multi-cancer detection (MCD) tests.

16 Jul 2025

Qureight analyze of Insilico Medicine's Phase IIa rentosertib data support preliminary efficacy results and future trial expansion

Qureight, a techbio company accelerating drug development using its proprietary deep-learning image biomarkers and clinical data analytics platform, today announced the first results from a collaboration with Insilico Medicine ("Insilico"), a clinical-stage biotechnology company driven by generative AI, focused on rentosertib (ISM001-055), a novel TNIK inhibitor discovered using Insilico's generative AI approach, in development for the treatment of IPF.

16 Jul 2025

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

University of New Mexico researchers have received funding to launch an early-stage clinical trial of a vaccine engineered to clear pathological tau protein from the brains of patients suffering from Alzheimer's dementia.

15 Jul 2025

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Clinical Trial News and Research

Breakthrough gene therapy reverses genetic deafness across age groups

Cannabis and psychedelics rated most effective for symptom relief by eating disorder patients

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

New antibody therapy offers hope for fragile patients with Fanconi anemia

Amid PFAS fallout, a Maine doctor navigates medical risks with her patients

Walking faster offers a simple solution to age-related frailty

Prime editing reverses symptoms of severe childhood neurological disease

Combination of two cancer drugs could treat the most common form of dementia

Microbial therapy uses modified bacteria to target oxalate in the gut

New mRNA vaccine strategy awakens immune system to fight cancer

Heart failure and atrial fibrillation at the time of mitral valve repair linked to worse outcomes

Study recommends ondansetron for children with gastroenteritis-induced vomiting at home

AI-guided patient stratification boosts Alzheimer’s trial outcomes and efficiency

New surgical method could become an alternative for treating groin hernias in women

Nighttime avocado snack may support heart health in prediabetic adults

New data confirms efficacy of mitochondrial donation in preventing disease

endTB-Q trial highlights importance of individualized regimens

Fred Hutch leads national study on multi-cancer detection blood tests

Qureight analyze of Insilico Medicine's Phase IIa rentosertib data support preliminary efficacy results and future trial expansion

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

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