Kidney Failure News and Research

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Case Western Reserve University receives grant to research on glucose-responsive insulin

Case Western Reserve University's School of Medicine has received a nearly $1 million grant from The Leona M. and Harry B. Helmsley Charitable Trust's Type 1 diabetes program.

15 Mar 2013

Transfusion of older blood adversely affects patients undergoing cardiac surgery or critical care

Transfusion of donated blood more than three weeks old results in impaired blood vessel function, a new study of hospital patients shows.

11 Mar 2013

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Kidney failure affects 25 million individuals in the U.S. and many more throughout the world. Loss of kidney function means the majority of these patients must undergo dialysis treatments to remove excess fluids and waste products. Although dialysis therapy coupled with medication has improved the life expectancy for people with kidney failure, for unknown reasons, patients' risk of sudden heart failure and death remains 10 to 20 times greater than average.

7 Mar 2013

Lung congestion increases dialysis patients' risks of premature death or heart attacks

Asymptomatic lung congestion increases dialysis patients' risks of dying prematurely or experiencing heart attacks or other cardiac events, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

1 Mar 2013

Combined complement mutations affect individuals' risk of aHUS and prognosis

Certain gene mutations affect individuals' risk of developing a serious kidney condition, as well as their prognosis after being diagnosed with the disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

22 Feb 2013

New coronavirus could potentially be treated with immunotherapy

The new coronavirus that has emerged in the Middle East is well-adapted to infecting humans but could potentially be treated with immunotherapy, according to a study to be published on February 19 in mBio-, the online open-access journal of the American Society for Microbiology.

20 Feb 2013

Experts identify new gene responsible for spinal meningioma

Genetic medicine experts from Manchester Biomedical Research Centre at Saint Mary's Hospital and The University of Manchester have identified a new gene responsible for causing an inherited form of tumour, known as spinal meningioma.

From The University of Manchester 19 Feb 2013

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Microbes present in the gut can affect the severity of kidney disease brought on by melamine poisoning, according to an international study led by Professor Wei Jia at the University of North Carolina in collaboration with the research group of Professor Jeremy Nicholson at Imperial College London.

16 Feb 2013

Patients undergoing major vascular surgery procedures are at increased risk of stroke

Patients undergoing major vascular surgery procedures are at increased risk of stroke, leading to a high mortality rate and prolonged hospitalization, according to a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Feb 2013

Scientists identify specific cellular events that appear key to lupus

A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent weapon against the disease.

5 Feb 2013

African-Americans without private health insurance less likely to receive kidney transplants

African-Americans and individuals without private health insurance are less likely than others to receive a kidney transplant before requiring dialysis, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

1 Feb 2013

Dual-hormone artificial pancreas shows promise against type 1 diabetes

IRCM researchers, led by endocrinologist Dr. R-mi Rabasa-Lhoret, were the first to conduct a trial comparing a dual-hormone artificial pancreas with conventional diabetes treatment using an insulin pump and showed improved glucose levels and lower risks of hypoglycemia.

29 Jan 2013

Paper says hospitals that do treat patients with anemia have better outcomes

Up to one-third of patients undergoing surgery in Ontario have a treatable form of anemia but are not optimally treated for it.

28 Jan 2013

NSAIDs cause acute kidney injury in some children

Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are commonly used to treat pain and reduce fever in children. However, the use of NSAIDs has been shown to cause acute kidney injury (AKI) in some children

25 Jan 2013

Viewpoints: A 'fail safe' and a 'time bomb' in health law; Reason for 'optimism' about health costs?

Although Republicans are eager to repeal the entire 2010 healthcare reform law, they started the new session of Congress last week by taking aim at one provision in particular: the Independent Payment Advisory Board, a yet-to-be-named group of 15 presidential appointees from various healthcare disciplines that could play a key role in limiting the growth of Medicare spending. Critics argue that it's a bad idea and even un-American to put so much power in the hands of unelected bureaucrats.

23 Jan 2013

Galectin Therapeutics' GR-MD-02 reverses diabetic nephropathy in preclinical study

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today announced new preclinical data on the efficacy of anti-galectin therapy on diabetic kidney disease.

23 Jan 2013

Income disparities, segregation may account for survival differences in U.S. hemodialysis patients

Complex socioeconomic and residential factors may account for differences in survival between Black and White kidney failure patients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

19 Jan 2013

Atrial fibrillation increases risk of kidney failure in people with CKD

Many people who suffer from chronic kidney disease progressively lose their kidney function over time and eventually develop a condition called end-stage renal disease - the complete failure of the kidneys - placing them in need of lifelong dialysis or a kidney transplant.

18 Jan 2013

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

A drug that protects the kidneys of patients with chronic kidney disease does not seem to provide the same benefit to kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

11 Jan 2013

Study compares three treatment approaches in membranous nephropathy

The results of a pioneering UK-wide clinical trial that compared treatments for patients with a common type of kidney disease has found one to be significantly more effective. The results of the study, published online in The Lancet, will be recommended to clinicians worldwide as the most effective approach to treating the condition.

10 Jan 2013