Metabolites News and Research

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Potential applications of bioactive molecules present in fruit peels

A recent study published in Current Issues in Molecular Biology reviewed the potential biological applications of fruit peel extracts.

13 Jun 2022

The physiological relevance and effects of probable in vivo transformation of CBD to delta9-THC in humans

Researchers reviewed studies on the probable conversion of orally administered cannabidiol (CBD) to delta9-tetrahydrocannabinol (delta9-THC or THC) in humans.

10 Jun 2022

Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

A recent article posted to the Research Square* preprint server demonstrated that high body temperature elevates gut microbiota-reliant host resistance against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A viral infection.

10 Jun 2022

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

Successful treatment of cancer frequently depends on early detection. However, many cancers are detected late, often after metastasizing to other sites.

9 Jun 2022

Cognitive impairment and function in SARS-CoV-2 positive patients

Researchers assessed the association between post-acute COVID-19 cognitive impairment and kynurenine pathway activation.

9 Jun 2022

Diet rich in polyphenols can prevent inflammation in the elderly

Polyphenols in the foods that we eat can prevent inflammation in older people, since they alter the intestinal microbiota and induce the production of the indole 3-propionic acid (IPA), a metabolite derived from the degradation of tryptophan due to intestinal bacteria.

8 Jun 2022

Profound neuroinflammation associated with long COVID

Around 36 to 53% of coronavirus disease 2019 (COVID-19) patients develop persistent chronic symptoms, often referred to as long COVID or PASC.

7 Jun 2022

The effect of BNT162b2 mRNA COVID-19 vaccine on human semen

Scientists from Italy have recently analyzed the effect of the mRNA-based COVID-19 vaccine on the semen quality of adult men.

3 Jun 2022

UH expert in lupus reports two new discoveries

Two separate findings by a University of Houston nationally recognized expert in systemic lupus erythematosus (SLE or lupus), a chronic autoimmune disease that affects multiple organs including the kidneys, skin, joints and heart, are being reported in scientific and medical journals.

2 Jun 2022

Nectar of common plants could be used to help fight Leishmania infections

The nectar of common plants such as sunflower contain bioactive agents that can inhibit the growth of Leishmania and could be used to help fight the potentially fatal disease caused by the parasite, say researchers.

2 Jun 2022

New biomarker may enable rapid, inexpensive diagnosis of Parkinson's disease

Researchers at Kobe University and Hiroshima University have successfully developed a biomarker that will enable Parkinson's disease to be rapidly and inexpensively diagnosed from blood serum samples.

26 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood, publishing their results today in eLife.

24 May 2022

Comparison of COVID-induced ARDS and sepsis-induced ARDS

In a recent study posted to the medRxiv* preprint server, researchers compared the pathophysiology of coronavirus disease 2019 (COVID-19) and bacterial sepsis-induced acute respiratory distress syndrome (ARDS).

20 May 2022

Kyunurenic acid in cardiovascular therapy

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of kynurenic acid on ischemic damage to the heart.

19 May 2022

Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

A new study authored by Sambhawa Priya and other researchers offers a detailed look at the interactions between the gut microbiome of humans in health and disease.

19 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Intestinal micro-biodiversity is important for maintaining colorectal and general health. Imbalance in this microenvironment can result in chronic infections, even cancer.

10 May 2022

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an indicator for cancer and various other diseases.