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Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

In new research, scientists evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the remdesivir parent nucleoside (GS-441524) against viruses that cause diseases of human public health concern, including SARS-CoV-2.

10 Aug 2021

Children's Hospital Colorado announces participation in pivotal trial of synthetic restorative pulmonary valve

Children's Hospital Colorado today announced it has joined the Xplore2/Pivotal trial, and is actively enrolling patients for the first-ever pivotal trial of a synthetic restorative pulmonary valve.

9 Aug 2021

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

A new study describes the cytopathic episodes triggered by SARS-CoV-2 with virus replication processes in frozen-hydrated cells.

9 Aug 2021

Study offers new insights on coronary microvascular dysfunction

New research has shown abnormalities in the tiny blood vessels of human hearts in regions well beyond the large arteries with atherosclerotic blockages that trigger the need for stents or bypass surgery.

9 Aug 2021

Education and employment experiences in early adulthood play a role in later life cardiovascular health

New research published today in the Journal of Epidemiology and Community Health has found that education and employment experiences in early adulthood contribute to cardiovascular health inequalities in later life, independent of occupation and family income in mid-adulthood.

6 Aug 2021

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Using circulating tumor DNA to identify patients at risk of urothelial cancer relapse after surgical resection could help improve post-surgery treatment.

6 Aug 2021

Monoclonal antibody could inform development of pan-coronavirus vaccines

Researchers in the United States have demonstrated the potential of a monoclonal antibody to inform the design of pan-coronavirus vaccines that could prevent the outbreak of future pandemics such as coronavirus disease 2019 (COVID-19).

4 Aug 2021

Rigaku Acquires Life Science Imaging Equipment Manufacturer MILabs

Rigaku Corporation (Headquarters: Akishima-shi, Tokyo; President: Toshiyuki Ikeda; "Rigaku"), a leading manufacturer of X-ray analysis equipment, has acquired all issued shares of MILabs B.V. (Headquarters: Houten, The Netherlands; CEO and CSO: Dr. Frederik Beekman; “MILabs”)

From Rigaku Corporation 4 Aug 2021

Researchers develop nanofibrous filters that can capture and kill airborne coronaviruses under visible light irradiation

A new study discusses the development of photosensitized electrospun nanofibrous membranes capable of capturing and inactivating SARS-CoV-2 aerosols.

4 Aug 2021

Next-Generation Sequencing and the Diagnosis of Disease

In this interview, Professor John Rossen talks about next-generation sequencing and it's implications for the diagnosis of disease.

From Tecan 4 Aug 2021

New micro-credentials aim to improve breastfeeding experience for mums and their babies

The University of Western Australia is introducing two new online short courses in Lactology incorporating the latest in breastfeeding research, with the ultimate aim of improving the feeding experience for mums and their babies.

4 Aug 2021

Inhibition of SARS-CoV-2 replication in vitro by Losartan

A new study explores the use of Losartan to provide protection against COVID-19 pathogenesis.

3 Aug 2021

Diagnosis of viral infections using micro and nanoscale technologies

In a recent study, the authors provide a review on both micro- and nanoscale technologies that advanced the diagnosis of viral diseases.

3 Aug 2021

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

A device able to generate proteins identity card: this is the ambitious goal of the "PROTEIN ID" project, funded by the European Union with about 3 million euro for the next 3 years and coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology).

3 Aug 2021

EMA methodology alongside an intervention could be effective in supporting men who have sex with men

While much of the health research around men who have sex with men (MSM) involves HIV, these communities are at increased risk for other health problems including certain types of cancer, substance use and mental health issues.

3 Aug 2021

SwRI and UTSA collaborate to create computer model of heart's intricate inner structures

Southwest Research Institute and The University of Texas at San Antonio are collaborating to create a computer model of the intricate structures of the human heart as part of a larger effort to develop a new, potentially life-saving heart surgery.

3 Aug 2021

Anti-parasitic drug prevents pancreatic cancer's initiation, progression and metastasis in mice

As the third-most lethal cancer in the United States, with only a 1% five-year survival rate for people with its most aggressive form, pancreatic cancer has long been a target of researchers who search for ways to slow or stop its growth and spread.

3 Aug 2021

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers in the United States have described a novel antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being evaluated in clinical trials as a treatment for coronavirus disease 2019 (COVID-19).

2 Aug 2021

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

A pioneering study reports on the interaction of a tailored titanium oxide nanoparticle (NP) with the full-length SARS-CoV-2 non-structural protein 1 (nsp1). This should be of value in developing new therapeutic tools against coronaviruses that act by targeting their proteins. It could also help map the structure of activated proteins.

2 Aug 2021

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Scientists in the Netherlands recently conducted an open-level, randomized-controlled trial to evaluate the safety and immunogenicity of fractional intradermal doses of the mRNA-based COVID-19 vaccine mRNA-1273 (Moderna). The trial findings reveal that the fractional dose regimen of the Moderna vaccine is well tolerated and safe and is capable of inducing robust antibody responses in vaccine recipients. The study is currently available on the medRxiv* preprint server.

2 Aug 2021

micro News and Research

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

Children's Hospital Colorado announces participation in pivotal trial of synthetic restorative pulmonary valve

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

Study offers new insights on coronary microvascular dysfunction

Education and employment experiences in early adulthood play a role in later life cardiovascular health

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Monoclonal antibody could inform development of pan-coronavirus vaccines

Rigaku Acquires Life Science Imaging Equipment Manufacturer MILabs

Researchers develop nanofibrous filters that can capture and kill airborne coronaviruses under visible light irradiation

Next-Generation Sequencing and the Diagnosis of Disease

New micro-credentials aim to improve breastfeeding experience for mums and their babies

Inhibition of SARS-CoV-2 replication in vitro by Losartan

Diagnosis of viral infections using micro and nanoscale technologies

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

EMA methodology alongside an intervention could be effective in supporting men who have sex with men

SwRI and UTSA collaborate to create computer model of heart's intricate inner structures

Anti-parasitic drug prevents pancreatic cancer's initiation, progression and metastasis in mice

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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