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Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

As part of its Wave 1 Pipeline Market Opportunity Call, Takeda Pharmaceutical Company Limited provided an update on its pipeline portfolio, which has the potential to contribute significantly to revenue growth for the company over the next decade.

From Takeda 10 Dec 2020

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections?Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian.

10 Dec 2020

Risk of COVID infection in health care workers is driven by community exposure

Nurses only group with higher risk once community exposure considered. Largest cohort of health care worker risk for SARS CoV-2. Only high-flow oxygen therapy and hemodialysis linked to more antibodies to SARS-CoV-2.

10 Dec 2020

Proactive management of COVID-19 risk can support employees' return to work

A Journal of Prevention, Assessment & Rehabilitation, published by IOS Press, is committed to helping organizations manage the challenges they face during the COVID-19 pandemic by publishing robust, evidence-based research, and commentary. All articles featured here and in the WORK COVID-19 Collection are freely available.

9 Dec 2020

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

For people in wealthy countries, diarrhea is usually nothing more than an uncomfortable inconvenience for a few days. But for a poor child in a developing country, repeated bouts of diarrhea can lead to serious health consequences such as malnutrition, stunted growth and cognitive deficits.

9 Dec 2020

Imaging, morphologic metrics associated with pathologic response in pancreatic cancer patients

According to an open-access Editor's Choice article in ARRS' American Journal of Roentgenology (AJR), post-neoadjuvant therapy (NAT) changes in metabolic metrics from PET/MRI and morphologic metrics from CT were associated with pathologic response and overall survival in patients with pancreatic ductal adenocarcinoma (PDA).

9 Dec 2020

Physicians don't always recognize radiation therapy side effects in cancer patients

Physicians did not recognize side effects from radiation therapy in more than half of breast cancer patients who reported a significant symptom, a new study finds.

9 Dec 2020

Study provides a detailed understanding of the interplay between obesity and cancer

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.

9 Dec 2020

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes.

9 Dec 2020

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Older patients with hormone receptor-positive breast cancer who did not receive radiation therapy after breast-conserving surgery had higher rates of local recurrence but similar 10-year survival rates when compared to patients who received postoperative radiation therapy, according to updated 10-year data from the PRIME II study, presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema, and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Breast cancer survivors less likely to get pregnant than the general population

A large meta-analysis of breast cancer survivors of childbearing age indicated that they are less likely than the general public to get pregnant, and they face higher risk of certain complications such as preterm labor.

9 Dec 2020

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

After a median follow-up of 5.1 years, among women with lymph node-positive early-stage breast cancer and a recurrence score of 25 or lower who received adjuvant endocrine therapy with or without chemotherapy, postmenopausal patients had no added benefit from chemotherapy, while premenopausal patients who received chemotherapy had improved invasive disease-free survival (IDFS) and an early indication of improved overall survival (OS), according to data from the SWOG S1007 RxPONDER clinical trial presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

Study reveals new biomarker for amyotrophic lateral sclerosis

ALS is a fatal neurodegenerative disease causing a rapid loss of motor function, which usually results in a serious condition with early death within a few years.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

People with Bartonella infection exhibit neuropsychiatric symptoms, skin lesions

Bartonella bacteria are increasingly recognized as an emerging infectious disease threat. A new study by North Carolina State University researchers has found additional instances of Bartonella infection in humans who exhibited neuropsychiatric symptoms, a subset of whom also had skin lesions.

8 Dec 2020

GlycoNet scientists secure up to $4 million US investment to advance regenerative medicine

GlycoNet scientists Drs. Robert Ben and Jason Acker, who are revolutionizing the cryopreservation of cells, tissues and organs for human and veterinary therapies, have secured a $2-million USD equity investment for PanTHERA CryoSolutions (PanTHERA), a Canadian biotechnology start-up that they co-founded.

8 Dec 2020

Therapy News and Research

Beta-blockers show anti-inflammatory effects in cirrhosis

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Risk of COVID infection in health care workers is driven by community exposure

Proactive management of COVID-19 risk can support employees' return to work

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

Imaging, morphologic metrics associated with pathologic response in pancreatic cancer patients

Physicians don't always recognize radiation therapy side effects in cancer patients

Study provides a detailed understanding of the interplay between obesity and cancer

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Breast cancer survivors less likely to get pregnant than the general population

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

Tomatoes could become a new, natural source of Parkinson's disease drug

Study reveals new biomarker for amyotrophic lateral sclerosis

Repair protein may prevent damage to healthy cells during cancer therapy

People with Bartonella infection exhibit neuropsychiatric symptoms, skin lesions

GlycoNet scientists secure up to $4 million US investment to advance regenerative medicine

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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