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Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

In a new study published on the preprint server bioRxiv researchers characterized the crystal structure of the antibody-SARS-CoV-2 RBD complex in an attempt to find the epitope and the mechanism that enables cross-neutralization.

5 Aug 2020

NICE guideline advises GPs to stop prescribing opioids for chronic pain

Published today, the first ever NICE guideline on the treatment of chronic pain has said that GPs should not prescribe opioids and other medicines like paracetamol to patients because they could be ‘harmful’ and cause addiction.

5 Aug 2020

Potential antibody treatment for yellow fever developed in 7 months using Rapid Response Strategy

Yellow fever, an acute viral hemorrhagic disease transmitted by infected mosquitoes, infects about 200,000 people and causes an estimated 30,000 deaths each year.

5 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.

5 Aug 2020

Scientists develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas

5 Aug 2020

Scientists detect emergence and spread of artemisinin-resistant malaria parasites in Rwanda

Resistance to artemisinin, the main component of the current antimalarial treatments recommended by WHO, is already widespread in South-East Asia, but it had not previously been described in Africa.

5 Aug 2020

Regeneron's COVID-19 antibody-drug cocktail treats SARS-CoV-2 virus in animals

Now, Regeneron Pharmaceuticals says its COVID-19 antibody-drug cocktail under development prevented and treated the disease in monkeys and hamsters, showing promise that it may work in humans.

5 Aug 2020

Novel technology tests the presence of thin membrane protrusions on breast cancer cells

Researchers at the University of Maryland School of Medicine (UMSOM) have developed a novel technology to test for the presence of thin membrane protrusions called "microtentacles" on breast cancer cells, which can help predict whether a tumor is likely to spread.

5 Aug 2020

Interleukin-6 inhibitors appear to be a more effective treatment for COVID-19

New research from Boston Medical Center found that patients experiencing severe COVID-19 symptoms had improved outcomes when administered an Interleukin-6 (IL6ri) inhibitor, sarilumab or tocilizumab, given to mediate severe systemic inflammatory responses.

5 Aug 2020

New computational model can help determine drug viability

About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn's disease, end up becoming resistant or unresponsive to it.

5 Aug 2020

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

The National Cancer Institute has once again rated the Abramson Cancer Center of the University of Pennsylvania as "exceptional," the highest possible rating for an NCI-designated comprehensive cancer center.

4 Aug 2020

Autistic men have greater excitability in social brain regions than women, study reveals

New insight on differences in the brains of men and women with autism has been published today in the open-access journal eLife.

4 Aug 2020

Decoy receptor neutralizes SARS-CoV-2 virus in tissue cultures

As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they're exposed. A new study suggests luring the virus with a decoy - an engineered, free-floating receptor protein - binds the virus and blocks infection.

4 Aug 2020

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish National Cancer Research Centre, have made important findings of how some gliomas can acquire chemoresistance.

4 Aug 2020

Specifically designed cyclic peptide inhibitor shown to be active against SARS-CoV-2

A new bioRxiv study by a research group from the University of California Irvine shows in vitro activity and non-toxicity of the first-in-class cyclic peptide that inhibits the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – laying the groundwork for its use in the treatment of coronavirus disease (COVID-19).

4 Aug 2020

Drugs News and Research

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

NICE guideline advises GPs to stop prescribing opioids for chronic pain

Potential antibody treatment for yellow fever developed in 7 months using Rapid Response Strategy

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Scientists develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists detect emergence and spread of artemisinin-resistant malaria parasites in Rwanda

Regeneron's COVID-19 antibody-drug cocktail treats SARS-CoV-2 virus in animals

Novel technology tests the presence of thin membrane protrusions on breast cancer cells

Interleukin-6 inhibitors appear to be a more effective treatment for COVID-19

New computational model can help determine drug viability

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

Autistic men have greater excitability in social brain regions than women, study reveals

Decoy receptor neutralizes SARS-CoV-2 virus in tissue cultures

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

Specifically designed cyclic peptide inhibitor shown to be active against SARS-CoV-2

Study shows how amyloid fibrils in Alzheimer's dissociate with infrared laser irradiation

NIH-funded project to develop AI-based system to help doctors cure cancer

Researcher is exploring safer and more effective treatment for leukemia

Normal DNA repair process can lead to mutations in cancer

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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