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UMass Amherst biologists identify environmental sensing mechanism in cells

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

A new cell-based gene therapy approach to better treat patients with hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

28 Jul 2020

Fighting a pandemic is 500 times more expensive than the costs of preventive efforts

According to new research, the failure to protect tropical rain forests has cost trillions of dollars stemming from the coronavirus pandemic, which has wreaked economic havoc and caused historic levels of unemployment in the United States and around the world.

28 Jul 2020

Evolutionary origins of SARS-CoV-2 identified

By reconstructing the evolutionary history of SARS-CoV-2, the virus that is responsible for the COVID-19 pandemic, an international research team of Chinese, European and U.S. scientists has discovered that the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

Investigational drug for Alzheimer's disease may help autistic children

An extensive international study led by Prof. Illana Gozes of Tel Aviv University's Department of Human Molecular Genetics and Biochemistry found deposits of the tau protein typically found in Alzheimer's patients in tissues taken from the postmortem brain of a 7-year-old autistic child.

28 Jul 2020

Artificial intelligence can expedite Alzheimer's diagnosis, improve patient prognosis

Artificial intelligence (AI) could help to diagnose Alzheimer's faster and improve patient prognosis, a new study from the University of Sheffield has revealed.

28 Jul 2020

Study reveals new mechanism that fuels cancer adaptation

Collaborative Cancer Research UK-funded studies from University of Oxford researchers have uncovered a new mechanism by which cancer cells adapt to the stresses they encounter as they grow and respond to therapies.

28 Jul 2020

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

28 Jul 2020

Study: Mosquitoes species are attracted and repelled by light at different times of day

In a new study, researchers found that night- versus day-biting species of mosquitoes are behaviorally attracted and repelled by different colors of light at different times of day.

28 Jul 2020

Simultaneous mutation of two nonessential genes can cause cancer cell death

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes - neither of which is on its own vital to cell survival - can cause cancer cell death.

28 Jul 2020

Exploiting 'synthetic lethality' to identify cancer targets

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

Population screening has potential to identify individuals at risk for inherited genetic conditions

In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke.

27 Jul 2020

Study reveals molecular cause underlying rare genetic disorder

Virginia Tech scientists have revealed how a nonfunctioning version of an ordinary gene impairs brain structure and function. The findings help explain a genetic form of microcephaly -- a condition where babies' heads are small and grow more slowly than their peers.

27 Jul 2020

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

27 Jul 2020

Overweight, obesity linked with low semen quality parameters

Infertility affects between 10 and 15% of all couples of reproductive ages and can be caused by a wide variety of factors: genetic, physiological, environmental and nutritional.

27 Jul 2020

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Clinician-scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have demonstrated a way to improve the speed, handling time and cost of COVID-19 laboratory tests.

27 Jul 2020

Continuous survival of neurons is intrinsically programmed during development

When our neurons -- the principle cells of the brain -- die, so do we.Most neurons are created during embryonic development and have no "backup" after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with nerve cells.

25 Jul 2020

New book provides details about different types of fetal cardiac abnormalities

In Perinatal Cardiology, fetal cardiology experts provide key information on tools for fetal evaluation through echocardiography / cardiac ultrasonography, with a primary focus on the nature and prenatal detection of structural and functional cardiac heart defects (CHDs).

25 Jul 2020

Genetic News and Research

UMass Amherst biologists identify environmental sensing mechanism in cells

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

A new cell-based gene therapy approach to better treat patients with hemophilia A

Fighting a pandemic is 500 times more expensive than the costs of preventive efforts

Evolutionary origins of SARS-CoV-2 identified

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Investigational drug for Alzheimer's disease may help autistic children

Artificial intelligence can expedite Alzheimer's diagnosis, improve patient prognosis

Study reveals new mechanism that fuels cancer adaptation

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

Study: Mosquitoes species are attracted and repelled by light at different times of day

Simultaneous mutation of two nonessential genes can cause cancer cell death

Exploiting 'synthetic lethality' to identify cancer targets

Population screening has potential to identify individuals at risk for inherited genetic conditions

Study reveals molecular cause underlying rare genetic disorder

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

Overweight, obesity linked with low semen quality parameters

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Continuous survival of neurons is intrinsically programmed during development

New book provides details about different types of fetal cardiac abnormalities

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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