Protein C News and Research

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Novel method allows rapid, absolute quantification of viral nucleic acids

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an Interdisciplinary Research Group at the Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have developed a new method for rapid and accurate detection of viral nucleic acids - a breakthrough that can be easily adapted to detect different DNA/RNA targets in viruses like the coronavirus.

7 Jun 2021

Experimental monoclonal antibody could be a new weapon against HIV epidemic

An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows.

7 Jun 2021

Natural products show promise against COVID-19 via iron chelation

Researchers at the University of Catania in Italy investigated whether natural compounds could prevent disease progression. Their study published in the Journal of Clinical Medicine found that iron chelators and protease inhibitors can counteract SARS-CoV-2 infection.

7 Jun 2021

The genetic diversity of SARS-CoV-2 in the USA

In a research paper recently uploaded to the preprint server medRxiv by Capoferri et al. (June 4th, 2021), the genetic diversity of SARS-CoV-2 through each phase is examined in detail using publicly available genomic data available from before 2021, highlighting the need to continuously track and assess the evolution of the virus to ensure the future efficacy of the currently available vaccines.

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

Study identifies new drug to halt dementia in athletes after repeated head injuries

A world-first international study led by the University of South Australia has identified a new drug to stop athletes from developing dementia after sustaining repeated head injuries in their career.

7 Jun 2021

Rice scientist wins NIH grant to model and analyze protein-ligand interactions in cancer research

Computer scientist Lydia Kavraki of Rice University's Brown School of Engineering has won a prestigious National Institutes of Health U01 grant to develop a new approach to model and analyze protein-ligand interactions in cancer research.

7 Jun 2021

Could COVID-19 vaccinations or prior infections protect against other coronaviruses?

A new study provides encouraging proof of the feasibility of this project, showing that both natural infection with and vaccination against SARS-CoV-2 are associated with an increase in cross-reactive antibodies against other CoVs.

7 Jun 2021

The great promise of antiviral peptides against SARS-CoV-2

A new study, recently published in the journal Viruses, describes the impressive evidence for the role of antimicrobial peptidse (AMPs) in the treatment of COVID-19.

7 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Plant-based and fish-based diets reduce the odds of severe COVID-19

Plant-based and pescatarian diets reduced the risk of severe COVID-19 infection by 73% and 59%, respectively.

7 Jun 2021

Seroprevalence study of SARS-CoV-2 infection in domestic cats

To monitor the occurrence of trans-species transmission, researchers from the Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Germany, conducted a survey of seroprevalence in domestic cats.

7 Jun 2021

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

The study findings reveal that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in abnormal modification of some lung proteins, which are subsequently transported to the brain via exosomes. In the brain, these modified lung proteins disrupt the normal functioning of proteins that are related to Parkinson’s disease.

7 Jun 2021

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

Once viewed merely as a producer of the cerebrospinal fluid (CSF) bathing the brain and spinal cord, the choroid plexus is now known to be a key player in brain development and immunity.

7 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

A new drug reduced tumor size in patients who have lung cancer with a specific, disease-causing change in the gene KRAS, a study found.

7 Jun 2021

Vaccination against SARS-CoV-2 with a single dose skin patch

Researchers from Australia recently reported a high-density microarray patch used to deliver a SARS-CoV-2 spike subunit vaccine to the skin directly. They used a combination of a SARS-CoV-2 spike protein vaccine candidate and the high-density microarray patch (HD-MAP) vaccine delivery platform.

7 Jun 2021

Researchers explore the science behind creating healthier, tastier plant-based protein products

As meat-eating continues to increase around the world, food scientists are focusing on ways to create healthier, better-tasting and more sustainable plant-based protein products that mimic meat, fish, milk, cheese and eggs.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes

An interesting new bioRxiv* preprint reports the suppression of monocyte glycolysis and cytokine production when exposed to the virus, following pretreatment with the commonly used drug, metformin.

6 Jun 2021

Protein C News and Research

Novel method allows rapid, absolute quantification of viral nucleic acids

Experimental monoclonal antibody could be a new weapon against HIV epidemic

Natural products show promise against COVID-19 via iron chelation

The genetic diversity of SARS-CoV-2 in the USA

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

Study identifies new drug to halt dementia in athletes after repeated head injuries

Rice scientist wins NIH grant to model and analyze protein-ligand interactions in cancer research

Could COVID-19 vaccinations or prior infections protect against other coronaviruses?

The great promise of antiviral peptides against SARS-CoV-2

A single blood-based biomarker can help indicate underlying neurodegeneration

Plant-based and fish-based diets reduce the odds of severe COVID-19

Seroprevalence study of SARS-CoV-2 infection in domestic cats

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

Vaccination against SARS-CoV-2 with a single dose skin patch

Researchers explore the science behind creating healthier, tastier plant-based protein products

Comparison of immunological profiles of SARS-CoV-2 variants

Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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