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FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

The U.S. Food and Drug Administration today approved Yondelis (trabectedin), a chemotherapy, for the treatment of specific soft tissue sarcomas (STS) – liposarcoma and leiomyosarcoma – that cannot be removed by surgery (unresectable) or is advanced (metastatic).

24 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

Patrolling monocytes may play anti-cancer role in the lung

One goal of immunotherapy is to rally a patient's often over-burdened immune cells to effectively attack a tumor. Among foot soldiers on the immune front line is a subpopulation of white blood cells called "patrolling monocytes," whose job is to cruise the bloodstream, cart off cellular debris, and block invasion of a less benign population of inflammatory cells.

23 Oct 2015

New combination treatment approved by FDA for metastatic pancreatic cancer

The U.S. Food and Drug Administration today approved Onivyde (irinotecan liposome injection), in combination with fluorouracil and leucovorin, to treat patients with advanced (metastatic) pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy.

23 Oct 2015

Lilly expands existing immuno-oncology collaboration with AstraZeneca

Eli Lilly and Company today announced an extension to their existing immuno-oncology collaboration exploring novel combination therapies for the treatment of patients with solid tumors.

22 Oct 2015

Scientists find new way to inhibit growth of lung cancer cells

Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth.

21 Oct 2015

Discovery may lead to new anti-metastasis therapies for advanced-stage brain cancer patients

It's no surprise that people enjoy warm places like Hawaii but may suffer in hostile locales such as Antarctica. A tumor suppressor gene called PTEN is similar in that it is affected by the microenvironments of certain bodily organs to which it travels.

20 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Takeda Pharmaceuticals, U.S.A., Inc., today announced that data highlighting the efficacy and safety of vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD), will be presented during the 2015 American College of Gastroenterology Annual Scientific Meeting in Honolulu, Hawaii, held on October 16-21.

20 Oct 2015

APBI brachytherapy improves overall survival in selected patients with early stage breast cancer

The Groupe Européen de Curiethérapie European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) today announced results from a prospective, randomized, multicenter phase III study comparing accelerated partial breast irradiation (APBI) with interstitial multicatheter brachytherapy to whole breast irradiation (WBI).

20 Oct 2015

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Lexicon Pharmaceuticals, Inc.'s telotristat etiprate, the first oral therapy in development for the treatment of carcinoid syndrome (CS), was associated with patient-reported improvements in social and physical function and emotional well-being according to new exit interview data from the Phase 3 TELESTAR study presented at the 2015 Neuroendocrine Tumor Society Annual Symposium in Austin, Texas.

19 Oct 2015

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

DelMar Pharmaceuticals, Inc., a biopharmaceutical company focused on the development and commercialization of new cancer therapies, announced that yesterday it presented positive preclinical data demonstrating the promising potential of its lead product candidate VAL-083 (dianhydrogalactitol) as a treatment for ovarian cancer.

19 Oct 2015

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

Immatics US, Inc., a subsidiary of Immatics Biotechnologies GmbH, and The University of Texas Health Science Center at Houston will collaborate on cellular manufacturing for adoptive cellular therapy (ACT) clinical trials.

19 Oct 2015

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Identifying a patient's genetic mutation led University of Arkansas for Medical Sciences (UAMS) physician-researcher Ling Gao, M.D., Ph.D., to an existing drug that eliminated the patient's stage IV Merkel-cell carcinoma. Gao's findings, made in collaboration with two other UAMS researchers, were published today in The New England Journal of Medicine.

19 Oct 2015

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

Researchers at Baylor Research Institute have identified a small RNA molecule that appears to enable certain colorectal cancers to become especially aggressive, resistant to treatment and likely to migrate and invade normal tissue.

19 Oct 2015

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

19 Oct 2015

University of Maryland develops GammaPod system to treat early-stage breast cancer

After more than a decade of research and development, researchers in the Department of Radiation Oncology at the University of Maryland School of Medicine will begin enrolling patients in the first clinical trial of GammaPod, a new high-precision, image-guided radiation therapy system specifically designed to treat early-stage breast cancer.

19 Oct 2015

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

The key to immune-based cancer therapies lies in the ability to exploit some weakness within the tumor and its environment or to elude cancer's offenses. Writing in the journal Scientific Reports, researchers led by a group from the Roswell Park Cancer Institute Center for Immunotherapy have shared new insights about a subset of T cells that appear to do both those things, inhibiting cancer growth at the same time that they enhance the tumor-killing powers of other immune cells.

19 Oct 2015

ViewRay obtains Korean regulatory approval for MRI-guided radiation therapy system

ViewRay, Inc. announced today that the company has received regulatory approval from the Ministry of Food and Drug Safety (MFDS) – formerly known as the Korean Food and Drug Administration – to sell its ViewRay system in Korea. On October 13, 2015, the first patient treatments commenced less than four weeks after the system completed installation at Seoul National University Hospital, a leading healthcare facility in Korea.

18 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

Tumor News and Research

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Patrolling monocytes may play anti-cancer role in the lung

New combination treatment approved by FDA for metastatic pancreatic cancer

Lilly expands existing immuno-oncology collaboration with AstraZeneca

Scientists find new way to inhibit growth of lung cancer cells

Discovery may lead to new anti-metastasis therapies for advanced-stage brain cancer patients

NAM announces election of three new members from UC San Diego School of Medicine

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

APBI brachytherapy improves overall survival in selected patients with early stage breast cancer

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

University of Maryland develops GammaPod system to treat early-stage breast cancer

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

ViewRay obtains Korean regulatory approval for MRI-guided radiation therapy system

New research raises hope for novel cancer immunotherapy

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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